(-)-Epicatechin acts as a potent agonist of the membrane androgen receptor, ZIP9 (SLC39A9), to promote apoptosis of breast and prostate cancer cells
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
(-)-Epicatechin acts as a potent agonist of the membrane androgen receptor, ZIP9 (SLC39A9), to promote apoptosis of breast and prostate cancer cells
Authors
Keywords
(-)-Epicatechin, (+)-Catechin, ZIP9, Membrane androgen receptor, Apoptosis, Cancer cells
Journal
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Volume -, Issue -, Pages 105906
Publisher
Elsevier BV
Online
2021-05-12
DOI
10.1016/j.jsbmb.2021.105906
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Apoptosis Induced by (−)-Epicatechin in Human Breast Cancer Cells is Mediated by Reactive Oxygen Species
- (2020) Fernando Pereyra-Vergara et al. MOLECULES
- Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer
- (2019) Yasuyoshi Miyata et al. MOLECULES
- Membrane androgen receptors (OXER1, GPRC6A AND ZIP9) in prostate and breast cancer: A comparative study of their expression
- (2019) Konstantina Kalyvianaki et al. STEROIDS
- Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial‐mesenchymal transition and inducing apoptosis
- (2019) Ya‐Nan Xue et al. PROSTATE
- Non-genomic mechanisms mediate androgen-induced PSD95 expression
- (2019) Yizhou Zhang et al. Aging-US
- Predictive Value of Low Testosterone Concentrations Regarding Coronary Heart Disease and Mortality in Men and Women – Evidence From The FINRISK 97 Study
- (2019) Tanja Zeller et al. JOURNAL OF INTERNAL MEDICINE
- Novel mechanism of endocrine disruption by fungicides through binding to the membrane androgen receptor, ZIP9 (SLC39A9), and antagonizing rapid testosterone induction of the intrinsic apoptotic pathway
- (2019) Peter Thomas et al. STEROIDS
- Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling
- (2019) Jinbo Chen et al. ONCOGENE
- ZIP9, a novel membrane androgen receptor and zinc transporter protein
- (2018) Peter Thomas et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- The Role of Catechins in Cellular Responses to Oxidative Stress
- (2018) Jurga Bernatoniene et al. MOLECULES
- N-terminal truncations in sex steroid receptors and rapid steroid actions
- (2018) Derek A. Schreihofer et al. STEROIDS
- ZIP9 but not the androgen receptor mediates testosterone-induced migratory activity of metastatic prostate cancer cells
- (2018) Ahmed Bulldan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Membrane Androgen Receptor ZIP9 Induces Croaker Ovarian Cell Apoptosis via Stimulatory G Protein Alpha Subunit and MAP Kinase Signaling
- (2017) Aubrey Converse et al. ENDOCRINOLOGY
- Phytosteroids beyond estrogens: Regulators of reproductive and endocrine function in natural products
- (2017) Matthew Dean et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Membrane androgen receptor characteristics of human ZIP9 (SLC39A) zinc transporter in prostate cancer cells: Androgen-specific activation and involvement of an inhibitory G protein in zinc and MAP kinase signaling
- (2017) Peter Thomas et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Green Tea Consumption and the Risk of Liver Cancer: A Meta-Analysis
- (2017) Chen-Xu Ni et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase
- (2017) Maliheh Moradzadeh et al. Pharmacological Reports
- Non-classical testosterone signaling mediated through ZIP9 stimulates claudin expression and tight junction formation in Sertoli cells
- (2016) Ahmed Bulldan et al. CELLULAR SIGNALLING
- Zinc as a possible preventive and therapeutic agent in pancreatic, prostate, and breast cancer
- (2016) Ba X. Hoang et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- A combination of (+)-catechin and (−)-epicatechin underlies the in vitro adipogenic action of Labrador tea (Rhododendron groenlandicum), an antidiabetic medicinal plant of the Eastern James Bay Cree pharmacopeia
- (2016) Hoda M. Eid et al. JOURNAL OF ETHNOPHARMACOLOGY
- Suppressive Effects of Tea Catechins on Breast Cancer
- (2016) Li-Ping Xiang et al. Nutrients
- The effects of (−)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER)
- (2015) Aldo Moreno-Ulloa et al. PHARMACOLOGICAL RESEARCH
- ASC-J9 Suppresses Castration-Resistant Prostate Cancer Growth through Degradation of Full-length and Splice Variant Androgen Receptors
- (2015) Shinichi Yamashita et al. NEOPLASIA
- Green Tea Catechins: Proposed Mechanisms of Action in Breast Cancer Focusing on the Interplay Between Survival and Apoptosis
- (2014) Eugenia Yiannakopoulou Anti-Cancer Agents in Medicinal Chemistry
- Cell membrane mediated (−)-epicatechin effects on upstream endothelial cell signaling: Evidence for a surface receptor
- (2014) Aldo Moreno-Ulloa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Identification and Characterization of Membrane Androgen Receptors in the ZIP9 Zinc Transporter Subfamily: II. Role of Human ZIP9 in Testosterone-Induced Prostate and Breast Cancer Cell Apoptosis
- (2014) Peter Thomas et al. ENDOCRINOLOGY
- Identification and Characterization of Membrane Androgen Receptors in the ZIP9 Zinc Transporter Subfamily: I. Discovery in Female Atlantic Croaker and Evidence ZIP9 Mediates Testosterone-Induced Apoptosis of Ovarian Follicle Cells
- (2014) A. Håkan Berg et al. ENDOCRINOLOGY
- Zinc Ionophore Activity of Quercetin and Epigallocatechin-gallate: From Hepa 1-6 Cells to a Liposome Model
- (2014) Husam Dabbagh-Bazarbachi et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Membrane Steroid Receptor-Mediated Action of Soy Isoflavones: Tip of the Iceberg
- (2014) Vladimir Ajdžanović et al. JOURNAL OF MEMBRANE BIOLOGY
- Green Tea and Anticancer Perspectives: Updates from Last Decade
- (2013) Masood Sadiq Butt et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- A review of the mechanisms and effectiveness of dietary polyphenols in reducing oxidative stress and thrombotic risk
- (2013) A. B. Santhakumar et al. JOURNAL OF HUMAN NUTRITION AND DIETETICS
- Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis
- (2011) Ali A Alshatwi JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Tea and cancer prevention: Epidemiological studies
- (2011) Jian-Min Yuan et al. PHARMACOLOGICAL RESEARCH
- Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: Effects of nandrolone decanoate and catechin
- (2011) Fernanda Carvalho Cavalari et al. STEROIDS
- Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo
- (2010) Phan LCHB Tran et al. BMC CANCER
- Green Tea Polyphenols and Metabolites in Prostatectomy Tissue: Implications for Cancer Prevention
- (2010) P. Wang et al. Cancer Prevention Research
- (−)-Epicatechin Activation of Endothelial Cell Endothelial Nitric Oxide Synthase, Nitric Oxide, and Related Signaling Pathways
- (2010) Israel Ramirez-Sanchez et al. HYPERTENSION
- Estrogen Receptor Alpha as a Key Target of Red Wine Polyphenols Action on the Endothelium
- (2010) Matthieu Chalopin et al. PLoS One
- The role of survivin and Bcl-2 in zinc-induced apoptosis in prostate cancer cells
- (2010) Ja Hyeon Ku et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Mechanism of Free Zn(2+) Enhancing Inhibitory Effects of EGCG on the Growth of PC-3 Cells: Interactions with Mitochondria
- (2009) Junguo Yang et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro
- (2009) J. McLarty et al. Cancer Prevention Research
- The important role of the apoptotic effects of zinc in the development of cancers
- (2009) Renty B. Franklin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Epigallocatechin-3-gallate affects the growth of LNCaP cells via membrane fluidity and distribution of cellular zinc
- (2009) Jun-guo Yang et al. Journal of Zhejiang University-SCIENCE B
- The Involvement of Bax in Zinc-Induced Mitochondrial Apoptogenesis in Malignant Prostate Cells
- (2008) Pei Feng et al. Molecular Cancer
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now