Article
Biochemistry & Molecular Biology
Killian Flegeau, Jing Jing, Romain Brusini, Melanie Gallet, Capucine Moreno, Lee Walker, Francois Bourdon, Jimmy Faivre
Summary: In this study, a novel rheological procedure was used to evaluate the degradation kinetics of TEOSYAL RHA((R)) filler in contact with HAase. Mathematical analyses were developed to determine the optimal time between injections and number of enzymatic units for maximizing degradation kinetics.
Review
Dermatology
Ploymanee Wongprasert, Cecile A. Dreiss, Gillian Murray
Summary: Soft-tissue augmentation using hyaluronic acid-based dermal fillers is a popular non-surgical treatment for restoring volume loss and filling fine lines. This article reviews the methods and parameters used to characterize dermal fillers, providing a useful guide for clinicians and injectors in selecting the optimal product for each patient.
DERMATOLOGIC THERAPY
(2022)
Article
Biochemistry & Molecular Biology
Sandip P. Patil, Leena P. Shirsath, Bhushan L. Chaudhari
Summary: A halotolerant bacterium isolated from dental caries was found to produce the enzyme hyaluronidase, which showed high activity and stability at pH 7.0 and 40 degrees C, as well as in 2M NaCl solution. The enzyme exhibited wide substrate specificity with hyaluronic acid as the best substrate.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Biochemistry & Molecular Biology
Aditya Kaul, Walker D. Short, Xinyi Wang, Sundeep G. Keswani
Summary: This article discusses the important role of hyaluronidases in human tissues, especially in promoting disease progression, and the potential benefits as clinical treatments currently and in the future.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Engineering, Biomedical
Fernanda Zamboni, Chun Kwok Wong, Maurice N. Collins
Summary: This article discusses the interaction between hyaluronic acid and pathogenic microorganisms, as well as the antimicrobial activity of different molecular weights of hyaluronic acid in biomedical and pharmaceutical applications. These studies are crucial for the development of next generation antimicrobial therapeutic strategies.
BIOACTIVE MATERIALS
(2023)
Article
Dermatology
Adriana Rodriguez-Valera, Francisco Nieto-Lopez
Summary: Aesthetic medicine emphasizes the importance of treatment efficiency and safety. However, adverse events such as vascular occlusion may occur. In this study, we propose the use of hyperbaric oxygenation treatment as an adjunct therapy to promote tissue oxygenation and regeneration after vascular occlusion caused by tissue fillers. The results show that hyperbaric oxygenation treatment is effective in improving tissue regeneration and preventing scarring or sequelae.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Chemistry, Physical
Pushap Raj, Seon-yeong Lee, Tae Yoon Lee
Summary: Bladder cancer is the leading cause of death in patients with genitourinary cancer. Elevated levels of hyaluronidase (HAase) can serve as an important biomarker for early diagnosis. A simple, sensitive, and ratiometric fluorescence assay for HAase detection has been developed, with a detection limit below normal human body fluid levels. The assay may be useful for diagnosing HAase-related diseases.
Review
Oncology
Kevin Domanegg, Jonathan P. Sleeman, Anja Schmaus
Summary: CEMIP is a protein that has been implicated in the pathogenesis of various diseases, particularly colorectal cancer. It plays a role in tumor growth and metastasis, and its expression is associated with poor prognosis. CEMIP contributes to tumor progression and metastasis through multiple mechanisms.
Review
Biochemistry & Molecular Biology
Salvatore Piero Fundaro, Giovanni Salti, Dennis Malvin Hernandez Malgapo, Silvia Innocenti
Summary: This review describes the rheological properties of hyaluronic acid (HA) fillers, aiming to help clinicians understand their characteristics and their likely correlation with clinical outcomes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Dermatology
Marina Aguilar-Gonzalez, Juan Davo-Cabrera, Nuria Rausell-Fontestad, Rafael Botella-Estrada, Enrique Espana-Gregori, Marta Perez-Lopez
Summary: The application of hyaluronidase in periocular skin leads to the presence of deposits, but does not alter the structure of elastin and collagen dermis.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Review
Materials Science, Multidisciplinary
Mujahid Iqbal, Aqeela Yasin, Ambreen Akram, Jing-An Li, Kun Zhang
Summary: Hyaluronic acid (HA) is a versatile material that can be modified to enhance its stability. Sulfated hyaluronic acid (S-HA) can be synthesized and has slower degradation by hyaluronidase compared with HA. S-HA has numerous applications in medical and cosmetic fields as biomaterials and coatings.
Article
Polymer Science
Stefano Pluda, Cecilia Salvagnini, Anna Fontana, Anna Marchetti, Alba Di Lucia, Devis Galesso, Cristian Guarise
Summary: This study investigates the modulation of hyaluronic acid dermal filler properties, particularly rheology, through process parameters such as modification degree, concentration, and molecular weight. The characterization of commercial hyaluronic acid injectables provides insights into their clinical effects and correlations with in vitro parameters. The findings emphasize the impact of hydrogel composition, rheological properties, and needle size on injectability and fibroblast recognition.
Article
Biophysics
Martin Sindelar, Jana Jilkova, Lukas Kubala, Vladimir Velebny, Kristyna Turkova
Summary: Hyaluronan is a crucial component in the human body with various applications in biological processes and medical fields. Hyaluronidases and hyaluronate lyases play significant roles in hyaluronan degradation, showing diversity in structure and function properties.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Surgery
Jun Zhuang, Qiaoyuan Zheng, Jintian Hu
Summary: This article reports a case of complications following hyaluronic acid augmentation in the temple and intrahairline regions. The patient received hyaluronidase treatment and showed improvement during follow-up.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Article
Dermatology
Raffaele Rauso, Nicola Zerbinati, Romolo Fragola, Giovanni Francesco Nicoletti, Gianpaolo Tartaro
Summary: HYAL has the capability to degrade crosslinked HA injected into human vessels, relieving vascular obstruction. In case of embolism, multiple high doses of HYAL may be required to restore blood flow.
DERMATOLOGIC SURGERY
(2021)
Letter
Surgery
Arif Tri Prasetyo, Lisa Y. Hasibuan, Kevin Leonard Suryadinata
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Peter J. Nicksic, D'Andrea T. Donnelly, Weifeng Zeng, Allison J. Seitz, Samuel O. Poore, Aaron J. Suminski, Aaron M. Dingle
Summary: The study demonstrates that trigeminal nerve stimulation (TNS) or peripheral nerve stimulation (PNS) can improve functional outcomes of peripheral nerve injury in rats. This finding is important in translating the therapy as a non-invasive treatment for high, mixed nerve injuries in humans.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
K. Can Bayezid, Suat Morkuzu, Erdem Karabulut, Adam Bajus, Libor Streit
Summary: This study compared the spontaneity outcomes of the most preferred neurotization methods in facial reanimation surgery. The results showed that dual innervation and contralateral facial nerve-driven strategies achieved the most promising outcomes, while motor nerve to the masseter had lower potential to elicit spontaneous smile.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Letter
Surgery
Hinpetch Daungsupawong, Viroj Wiwanitkit
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Zidi Yu, Ziwei Zhang, Xiancheng Wang, Dandan Song, Quanding Yan, Yang Sun, Xiang Xiong, Xianxi Meng, Wenbo Li, Zhongjie Yi
Summary: Pathological psychologies such as anxiety, depression, and body dysmorphic disorder (BDD) are common in female patients scheduled to undergo rhinoplasty. BDD is more likely to be associated with depression. Rhinoplasty has little psychological impact on patients, but female patients with BDD are more likely to be dissatisfied with the surgery.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Lei Wang, Qian Zhu, Yuanyuan Zhang, Yulin Miao, Huan Liu, Fengli Gao
Summary: This comparative observational study found that microscopic varicocoelectomy had higher sperm motility and showed significant improvements in certain postoperative parameters compared to laparoscopic varicocoelectomy. Neither group experienced testicular atrophy.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Mohamed Dalmar, Mohamed El Sheikh, Richard Baker, Rajan Uppal
Summary: This study analyzed complications following cosmetic surgeries managed by plastic surgery services at Heatherwood and Wexham Park hospitals in 2022, including procedures performed internationally. The majority of complications were related to breast cosmetic surgery and abdominoplasties, with the most common complications being wound dehiscence, post-operative infection, and seromas. Turkey was the most popular country selected for surgery, and there is a need to increase public awareness of the risks involved in seeking international options and how to choose suitable clinics.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Editorial Material
Surgery
Rohun Gupta, Lawson E. Spence, Peter K. Firouzbakht, Brian A. Mailey
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Alexandre Mendonca Munhoz, Ary de Azevedo Marques Neto, Joao Maximiliano, Murillo Fraga
Summary: This study investigated the outcomes of silicone implants in breast augmentation and found that ergonomic style implants can achieve favorable results with lower complication rates.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Lee H. Kilmer, Allan A. Weidman, Brent R. Degeorge, John T. Stranix, Chris A. Campbell
Summary: The study aims to compare the oncologic, medical, and surgical outcomes of lumpectomy and oncoplastic breast reduction surgery (OBRS) on a national scale. A database was used to analyze patient data and match them based on various factors. The results showed that lumpectomy patients had higher rates of repeat lumpectomy or subsequent mastectomy, while OBRS patients had higher rates of surgical complications but fewer medical complications. Logistic regression analysis revealed that OBRS was associated with a decreased likelihood of repeat lumpectomy. Although OBRS was associated with increased wound complications, medical complications were found to occur less frequently.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Review
Surgery
M. Guiotto, C. M. Oranges, M. Cherubino, M. Maruccia, P. Tedeschi, D. F. Kalbermatten, W. Raffoul, P. G. di Summa
Summary: This study evaluated different surgical approaches for neoumbilicoplasty and correlated them with specific surgical needs. The results showed that direct suture, single flap, and multiple flap techniques can achieve overall satisfactory cosmetic outcomes with a low rate of surgical complications. Different surgical techniques are suitable for different patient populations and surgical scenarios.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Review
Surgery
Samuel Knoedler, Giuseppe Sofo, Barbara Kern, Konstantin Frank, Sebastian Cotofana, Sarah von Isenburg, Soren Konneker, Francesco Mazzarone, Amir H. Dorafshar, Leonard Knoedler, Michael Alfertshofer
Summary: This study compared real patient feedback with ChatGPT-generated reviews for the top five US plastic surgery procedures. It found that analyzing the emotional tone and review length can help differentiate real from fake reviews, and ChatGPT-generated reviews can convincingly deceive commercial AI detection software.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Gerlya Asirova, Jan Wynands, Sergey Frolov, Diana Almeida, Pavel Davydenko, Salem Madina
Summary: By assessing the development and growth of costal cartilage, the optimal age for ear reconstruction surgery in the Russian population was determined to be 10 years and older.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Letter
Surgery
S. Curran, E. Heffernan, S. Connolly, K. Levins, K. Cronin, R. Dolan
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)
Article
Surgery
Soo Min Cha, Ashwin Pai, Hyun Jong Lee, Hyun Dae Shin
Summary: In this retrospective case series, we found that non-vascularized iliac bone graft longer than 3 cm had satisfactory clinical outcomes in the treatment of non-union of the upper extremities.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2024)