Type I IFN signaling facilitates the development of IL-10-producing effector CD8+T cells during murine influenza virus infection

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

IL-10 inhibits neuraminidase-activated TGF-β and facilitates Th1 phenotype during early phase of infection

(2015) Avijit Dutta et al.   Nature Communications

Mucosal Immune Responses Predict Clinical Outcomes during Influenza Infection Independently of Age and Viral Load

(2014) Christine M. Oshansky et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Type I Interferon Protects Antiviral CD8+ T Cells from NK Cell Cytotoxicity

(2014) Haifeng C. Xu et al.   IMMUNITY

Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1

(2014) Josh Crouse et al.   IMMUNITY

Type I Interferon Plays Opposing Roles in Cytotoxicity and Interferon-γ Production by Natural Killer and CD8+ T Cells after Influenza A Virus Infection in Mice

(2014) Yojiro Arimori et al.   Journal of Innate Immunity

Impact of Inflammatory Cytokines on Effector and Memory CD8+ T Cells

(2014) Marie T. Kim et al.   Frontiers in Immunology

Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice

(2013) Yojiro Arimori et al.   ANTIVIRAL RESEARCH

Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation

(2013) Shuyu Yao et al.   IMMUNITY

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

(2013) Gabriel R. Starbeck-Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cytokine-Dependent Induction of CD4+ T cells with Cytotoxic Potential during Influenza Virus Infection

(2013) L. Hua et al.   JOURNAL OF VIROLOGY

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

Role of T cell immunity in recovery from influenza virus infection

(2013) Jie Sun et al.   Current Opinion in Virology

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

IL-10 Regulates Viral Lung Immunopathology during Acute Respiratory Syncytial Virus Infection in Mice

(2012) Jens Loebbermann et al.   PLoS One

Influenza-Infected Neutrophils within the Infected Lungs Act as Antigen Presenting Cells for Anti-Viral CD8+ T Cells

(2012) Matthew M. Hufford et al.   PLoS One

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

Highly Activated Cytotoxic CD8 T Cells Express Protective IL-10 at the Peak of Coronavirus-Induced Encephalitis

(2011) K. Trandem et al.   JOURNAL OF IMMUNOLOGY

CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs

(2011) Jie Sun et al.   NATURE IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

T cell responses during influenza infection: getting and keeping control

(2011) Taeg S. Kim et al.   TRENDS IN IMMUNOLOGY

Induction and evasion of type I interferon responses by influenza viruses

(2011) Adolfo García-Sastre   VIRUS RESEARCH

Autocrine Regulation of Pulmonary Inflammation by Effector T-Cell Derived IL-10 during Infection with Respiratory Syncytial Virus

(2011) Jie Sun et al.   PLoS Pathogens

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages

(2010) S. S. Iyer et al.   JOURNAL OF IMMUNOLOGY

A Detrimental Effect of Interleukin-10 on Protective Pulmonary Humoral Immunity during Primary Influenza A Virus Infection

(2010) K. Sun et al.   JOURNAL OF VIROLOGY

IFNγ-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment

(2010) Ellen M. Palmer et al.   VIROLOGY

Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose

(2009) Margarida Saraiva et al.   IMMUNITY

Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity

(2009) B. Moltedo et al.   JOURNAL OF IMMUNOLOGY

IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

(2009) K. K. McKinstry et al.   JOURNAL OF IMMUNOLOGY

IFN Regulatory Factor 4 Regulates the Expression of a Subset of Th2 Cytokines

(2009) A.-N. N. Ahyi et al.   JOURNAL OF IMMUNOLOGY

Nonredundant Roles for B Cell-Derived IL-10 in Immune Counter-Regulation

(2009) R. Madan et al.   JOURNAL OF IMMUNOLOGY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Pulmonary Eosinophilia Is Attenuated by Early Responding CD8+ Memory T Cells in a Murine Model of RSV Vaccine-Enhanced Disease

(2009) Whitney W. Stevens et al.   VIRAL IMMUNOLOGY