Selective Laser Sintering 3-Dimensional Printing as a Single Step Process to Prepare Amorphous Solid Dispersion Dosage Forms for Improved Solubility and Dissolution Rate

Systematic screening of pharmaceutical polymers for hot melt extrusion processing: a comprehensive review

(2020) Rishi Thakkar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Congruent release of drug and polymer from amorphous solid dispersions: insights into the role of drug-polymer hydrogen bonding, surface crystallization and glass transition

(2020) Sugandha Saboo et al.   MOLECULAR PHARMACEUTICS

Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron

(2020) Nour Allahham et al.   Pharmaceutics

Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol® Enabled Amorphous Solid Dispersions

(2020) Urvi Gala et al.   Pharmaceutics

Influence of Carbamazepine Dihydrate on the Preparation of Amorphous Solid Dispersions by Hot Melt Extrusion

(2020) Xiangyu Ma et al.   Pharmaceutics

A Comparison Between Lab-Scale and Hot-Melt-Extruder-Based Anti-inflammatory Ointment Manufacturing

(2020) Rishi Thakkar et al.   AAPS PHARMSCITECH

3D printing: Principles and pharmaceutical applications of selective laser sintering

(2020) Atheer Awad et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Assessment of 3D printing using fused deposition modeling and selective laser sintering for a circular economy

(2020) K. DePalma et al.   JOURNAL OF CLEANER PRODUCTION

In Vitro and In Vivo Behaviors of KinetiSol and Spray-Dried Amorphous Solid Dispersions of a Weakly Basic Drug and Ionic Polymer

(2020) Scott V. Jermain et al.   MOLECULAR PHARMACEUTICS

Novel On-Demand 3-Dimensional (3-D) Printed Tablets Using Fill Density as an Effective Release-Controlling Tool

(2020) Rishi Thakkar et al.   Polymers

Homogeneity of Amorphous Solid Dispersions – An Example with KinetiSol®

(2019) Scott V. Jermain et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Characterization of amorphous solid dispersions: An update

(2019) Xiangyu Ma et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

3D Printed Pellets (Miniprintlets): A Novel, Multi-Drug, Controlled Release Platform Technology

(2019) Atheer Awad et al.   Pharmaceutics

Insights into the Dissolution Mechanism of Ritonavir–Copovidone Amorphous Solid Dispersions: Importance of Congruent Release for Enhanced Performance

(2019) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Effect of screw profile and processing conditions on physical transformation and chemical degradation of gabapentin during twin-screw melt granulation

(2019) Nada Kittikunakorn et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Insights into the Dissolution Behavior of Ledipasvir–Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions

(2019) Chailu Que et al.   MOLECULAR PHARMACEUTICS

The role of the screw profile on granular structure and mixing efficiency of a high-dose hydrophobic drug formulation during twin screw wet granulation

(2019) Shahab Kashani Rahimi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solid-state analysis of amorphous solid dispersions: Why DSC and XRPD may not be regarded as stand-alone techniques

(2019) Sien Dedroog et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Generation of a Weakly Acidic Amorphous Solid Dispersion of the Weak Base Ritonavir with Equivalent In Vitro and In Vivo Performance to Norvir Tablet

(2018) Daniel J. Ellenberger et al.   AAPS PHARMSCITECH

Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – An update

(2018) Scott V. Jermain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Predicting physical stability of ternary amorphous solid dispersions using specific mechanical energy in a hot melt extrusion process

(2018) Masataka Hanada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

3D printing of drug-loaded gyroid lattices using selective laser sintering

(2018) Fabrizio Fina et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Probing the Interplay between Amorphous Solid Dispersion Stability and Polymer Functionality

(2018) Derek S. Frank et al.   MOLECULAR PHARMACEUTICS

Physical Stability of Amorphous Solid Dispersions: a Physicochemical Perspective with Thermodynamic, Kinetic and Environmental Aspects

(2018) Xia Lin et al.   PHARMACEUTICAL RESEARCH

3D printed drug products: Non-destructive dose verification using a rapid point-and-shoot approach

(2018) Sarah J Trenfield et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In-process measurement and monitoring of a polymer laser sintering powder bed with fringe projection

(2018) Nicholas Southon et al.   MATERIALS & DESIGN

Effect of plasticizers on manufacturing ritonavir/copovidone solid dispersions via hot-melt extrusion: Preformulation, physicochemical characterization, and pharmacokinetics in rats

(2018) Yanna Zhao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Selective laser sintering (SLS) 3D printing of medicines

(2017) Fabrizio Fina et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impact of Polymer Type and Relative Humidity on the Long-Term Physical Stability of Amorphous Solid Dispersions

(2017) Kristin Lehmkemper et al.   MOLECULAR PHARMACEUTICS

Phase Behavior of Ritonavir Amorphous Solid Dispersions during Hydration and Dissolution

(2017) Hitesh S. Purohit et al.   PHARMACEUTICAL RESEARCH

Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy

(2017) Hitesh S. Purohit et al.   PHARMACEUTICAL RESEARCH

Effect of colloidal silica on rheological properties of common pharmaceutical excipients

(2016) Diana Majerová et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Micro-scale prediction method for API-solubility in polymeric matrices and process model for forming amorphous solid dispersion by hot-melt extrusion

(2016) Esther S. Bochmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Enabling thermal processing of ritonavir–polyvinyl alcohol amorphous solid dispersions by KinetiSol® Dispersing

(2016) Justin S. LaFountaine et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Laser irradiation to produce amorphous pharmaceuticals

(2016) Varin Titapiwatanakun et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solvent-shift strategy to identify suitable polymers to inhibit humidity-induced solid-state crystallization of lacidipine amorphous solid dispersions

(2016) Mengchi Sun et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solubility Advantage (and Disadvantage) of Pharmaceutical Amorphous Solid Dispersions

(2016) Siyuan Huang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Initial Drug Dissolution from Amorphous Solid Dispersions Controlled by Polymer Dissolution and Drug-Polymer Interaction

(2016) Yuejie Chen et al.   PHARMACEUTICAL RESEARCH

Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A Review

(2015) Justin S. LaFountaine et al.   AAPS PHARMSCITECH

Amorphous Solid Dispersions: Utilization and Challenges in Drug Discovery and Development

(2015) Yan He et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

G.L. Amidon, H. Lennernas, V.P. Shah, and J.R. Crison. A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of In Vitro Drug Product Dissolution and In Vivo Bioavailability, Pharm Res 12, 413–420, 1995—Backstory of BCS

(2014) Vinod P. Shah et al.   AAPS Journal

Evaluation of the recrystallization kinetics of hot-melt extruded polymeric solid dispersions using an improved Avrami equation

(2014) Xin Feng et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and Relaxometry

(2014) Amrit Paudel et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound

(2013) Po-Chang Chiang et al.   AAPS Journal

Drug–polymer intermolecular interactions in hot-melt extruded solid dispersions

(2012) Mohammed Maniruzzaman et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solid-State Nuclear Magnetic Resonance Study of the Physical Stability of Electrospun Drug and Polymer Solid Solutions

(2012) Blair Kathryn Brettmann et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Solid Dispersion as an Approach for Bioavailability Enhancement of Poorly Water-Soluble Drug Ritonavir

(2010) Shilpi Sinha et al.   AAPS PHARMSCITECH

Analysis of Amorphous Solid Dispersions Using 2D Solid-State NMR and1HT1Relaxation Measurements

(2010) Tran N. Pham et al.   MOLECULAR PHARMACEUTICS

Effect of particle properties on the flowability of ibuprofen powders

(2008) L.X. Liu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS