Mutations in RIT1 cause Noonan syndrome with possible juvenile myelomonocytic leukemia but are not involved in acute lymphoblastic leukemia

Cancer spectrum and frequency among children with Noonan, Costello and cardio-facio-cutaneous syndromes

(2015) C P Kratz et al.   BRITISH JOURNAL OF CANCER

Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome

(2015) Viviana Cordeddu et al.   HUMAN MUTATION

Rare variants inSOS2andLZTR1are associated with Noonan syndrome

(2015) Guilherme Lopes Yamamoto et al.   JOURNAL OF MEDICAL GENETICS

Contribution ofRIT1mutations to the pathogenesis of Noonan syndrome: Four new cases and further evidence of heterogeneity

(2014) Monika Gos et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Further evidence of the importance ofRIT1in Noonan syndrome

(2014) Débora R. Bertola et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis

(2014) E. Flex et al.   HUMAN MOLECULAR GENETICS

Juvenile myelomonocytic leukaemia and Noonan syndrome

(2014) Marion Strullu et al.   JOURNAL OF MEDICAL GENETICS

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Oncogenic RIT1 mutations in lung adenocarcinoma

(2014) A H Berger et al.   ONCOGENE

Next-generation sequencing identifies rare variants associated with Noonan syndrome

(2014) P.-C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gain-of-Function Mutations in RIT1 Cause Noonan Syndrome, a RAS/MAPK Pathway Syndrome

(2013) Yoko Aoki et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The RASopathies

(2013) Katherine A. Rauen   Annual Review of Genomics and Human Genetics

Rit subfamily small GTPases: Regulators in neuronal differentiation and survival

(2013) Geng-Xian Shi et al.   CELLULAR SIGNALLING

Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies

(2013) I Gómez-Seguí et al.   LEUKEMIA

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

(2013) Guangwu Guo et al.   NATURE GENETICS

Are RASopathies new monogenic predisposing conditions to the development of systemic lupus erythematosus? Case report and systematic review of the literature

(2013) Brigitte Bader-Meunier et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Rit GTPase Signaling Promotes Immature Hippocampal Neuronal Survival

(2012) W. Cai et al.   JOURNAL OF NEUROSCIENCE

Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes

(2011) Christian P. Kratz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Spectrum of Mutations in Noonan Syndrome and Their Correlation with Phenotypes

(2011) Beom Hee Lee et al.   JOURNAL OF PEDIATRICS

Noonan Syndrome: Clinical Features, Diagnosis, and Management Guidelines

(2010) A. A. Romano et al.   PEDIATRICS

SOS1 and PTPN11 mutations in five cases of Noonan syndrome with multiple giant cell lesions

(2009) Claire Beneteau et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Malignant Diseases in Noonan Syndrome and Related Disorders

(2009) Henrik Hasle   HORMONE RESEARCH