The Properties and Role of O-Acyl-ω-hydroxy Fatty Acids and Type I-St and Type II Diesters in the Tear Film Lipid Layer Revealed by a Combined Chemistry and Biophysics Approach

Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease

(2020) Masatoshi Miyamoto et al.   eLife

Interactions of polar lipids with cholesteryl ester multilayers elucidate tear film lipid layer structure

(2020) Riku O. Paananen et al.   Ocular Surface

Investigating the Role of Specific Tear Film Lipids Connected to Dry Eye Syndrome: A Study on O-Acyl-ω-hydroxy Fatty Acids and Diesters

(2019) Helena C. Bland et al.   LANGMUIR

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids

(2018) Sarah E. Hancock et al.   JOURNAL OF LIPID RESEARCH

Tear-Film Evaporation Rate from Simultaneous Ocular-Surface Temperature and Tear-Breakup Area

(2018) Thomas J. Dursch et al.   OPTOMETRY AND VISION SCIENCE

Studies towards the Synthesis of the Antibiotic Tetrodecamycin

(2018) Victor Lee et al.   SYNLETT

Human Meibum Age, Lipid–Lipid Interactions and Lipid Saturation in Meibum from Infants

(2017) Samiyyah Sledge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TFOS DEWS II Tear Film Report

(2017) Mark D.P. Willcox et al.   Ocular Surface

TFOS DEWS II Epidemiology Report

(2017) Fiona Stapleton et al.   Ocular Surface

TFOS DEWS II Definition and Classification Report

(2017) Jennifer P. Craig et al.   Ocular Surface

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry

(2017) Jennifer Greaves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications of nuclear magnetic resonance in lipid analyses: An emerging powerful tool for lipidomics studies

(2017) Jingbo Li et al.   PROGRESS IN LIPID RESEARCH

Influence of Meibomian Gland Expression Methods on Human Lipid Analysis Results

(2016) Carolina M.E. Kunnen et al.   Ocular Surface

Economic and Humanistic Burden of Dry Eye Disease in Europe, North America, and Asia: A Systematic Literature Review

(2016) Marguerite McDonald et al.   Ocular Surface

Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers

(2016) Laurence Balas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An efficient total synthesis of leukotriene B4

(2015) Karoline Gangestad Primdahl et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Long-chain alkyltriazoles as antitumor agents: synthesis, physicochemical properties, and biological and computational evaluation

(2014) Vanessa Silva Gontijo et al.   MEDICINAL CHEMISTRY RESEARCH

Tear film lipids

(2013) Igor A. Butovich   EXPERIMENTAL EYE RESEARCH

13C and 1H NMR ester region resonance assignments and the composition of human infant and child meibum

(2013) Douglas Borchman et al.   EXPERIMENTAL EYE RESEARCH

An investigation of the likely role of (O-acyl) ω-hydroxy fatty acids in meibomian lipid films using (O-oleyl) ω-hydroxy palmitic acid as a model

(2013) Burkhardt S. Schuett et al.   EXPERIMENTAL EYE RESEARCH

Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome

(2013) Sin Man Lam et al.   JOURNAL OF LIPID RESEARCH

Synthesis and Characterization of Novel Diol, Diacid and Di-isocyanate from Oleic Acid

(2013) Latchmi Raghunanan et al.   JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY

Four Characteristics and a Model of an Effective Tear Film Lipid Layer (TFLL)

(2013) P. Ewen King-Smith et al.   Ocular Surface

Studies Related to Norway Spruce Galactoglucomannans: Chemical Synthesis, Conformation Analysis, NMR Spectroscopic Characterization, and Molecular Recognition of Model Compounds

(2012) Filip S. Ekholm et al.   CHEMISTRY-A EUROPEAN JOURNAL

Meibum Lipid Composition in Asians with Dry Eye Disease

(2011) Sin Man Lam et al.   PLoS One

An approach to the synthesis and attachment of scillabiose to steroids

(2011) Filip S. Ekholm et al.   STEROIDS

Facile One-Pot Two-Step Hydroxylation of Alkyl Halides and Alkyl Sulfonates via Acetate Intermediates

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

A short semi-synthesis and complete NMR-spectroscopic characterization of the naturally occurring lignan glycoside matairesinol 4,4′-di-O-β-d-diglucoside

(2010) Filip S. Ekholm et al.   CARBOHYDRATE RESEARCH

The Economic Burden of Dry Eye Disease in the United States: A Decision Tree Analysis

(2010) Junhua Yu et al.   CORNEA

Fully deprotected β-(1→2)-mannotetraose forms a contorted α-helix in solution: convergent synthesis and conformational characterization by NMR and DFT

(2010) Filip S. Ekholm et al.   NEW JOURNAL OF CHEMISTRY

Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids

(2010) Ghulam M. Maharvi et al.   TETRAHEDRON LETTERS

Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum

(2009) Igor A. Butovich et al.   JOURNAL OF LIPID RESEARCH