Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Pancreatic cancer cell–derived exosomal microRNA‐27a promotes angiogenesis of human microvascular endothelial cells in pancreatic cancer via BTG2

(2019) Dan Shang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes

(2019) Mitsuru Shinohara et al.   FASEB JOURNAL

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

(2018) Okiru Komine et al.   CELL DEATH AND DIFFERENTIATION

Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?

(2018) Aditya Rayasam et al.   IMMUNOLOGY

Cilostazol alleviates white matter degeneration caused by chronic cerebral hypoperfusion in mice: Implication of its mechanism from gene expression analysis

(2018) Ryo Ohtomo et al.   NEUROSCIENCE LETTERS

Post-stroke inflammation—target or tool for therapy?

(2018) Kate Lykke Lambertsen et al.   ACTA NEUROPATHOLOGICA

Tumor suppressors BTG1 and BTG2: Beyond growth control

(2018) Laurensia Yuniati et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Characteristics of primary rat microglia isolated from mixed cultures using two different methods

(2017) Li Lin et al.   Journal of Neuroinflammation

Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models

(2017) Yan Feng et al.   Journal of Neuroinflammation

APOE2eases cognitive decline during Aging: Clinical and preclinical evaluations

(2016) Mitsuru Shinohara et al.   ANNALS OF NEUROLOGY

Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development

(2016) E. Tijchon et al.   HAEMATOLOGICA

Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development

(2016) E. Tijchon et al.   HAEMATOLOGICA

Subcortical ischemic vascular disease: Roles of oligodendrocyte function in experimental models of subcortical white-matter injury

(2015) Akihiro Shindo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

(2015) Esther Tijchon et al.   PLoS One

Accumulation of cytolytic CD8+ T cells in B16-melanoma and proliferation of mature T cells in TIS21-knockout mice after T cell receptor stimulation

(2014) Min Sook Ryu et al.   EXPERIMENTAL CELL RESEARCH

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

(2014) Mukesh Kumar et al.   Journal of Neuroinflammation

Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids

(2014) Stefano Farioli-Vecchioli et al.   Frontiers in Cellular Neuroscience

Simple knockout by electroporation of engineered endonucleases into intact rat embryos

(2014) Takehito Kaneko et al.   Scientific Reports

Regulation of Btg2/TIS21/PC3 expression via reactive oxygen species–protein kinase C–ΝFκΒ pathway under stress conditions

(2013) Muhammad Imran et al.   CELLULAR SIGNALLING

Vismodegib Suppresses TRAIL-mediated Liver Injury in a Mouse Model of Nonalcoholic Steatohepatitis

(2013) Petra Hirsova et al.   PLoS One

TIS21/BTG2/PC3 accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2T68–p53S20 pathway

(2012) Kyu-Sung Choi et al.   DNA REPAIR

Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib

(2011) F Takahashi et al.   ONCOGENE

BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence

(2010) Keith Wheaton et al.   AGING CELL

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mouse Model Characterizing Features of Vascular Dementia With Hippocampal Atrophy

(2010) Keiko Nishio et al.   STROKE

Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner

(2009) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Systemic Lipopolysaccharide Protects the Brain from Ischemic Injury by Reprogramming the Response of the Brain to Stroke: A Critical Role for IRF3

(2009) B. Marsh et al.   JOURNAL OF NEUROSCIENCE

B-Cell Translocation Gene 2 Is Over-Expressed in Peri-Infarct Neurons after Ischaemic Stroke

(2009) M. Slevin et al.   PATHOBIOLOGY

Impaired Terminal Differentiation of Hippocampal Granule Neurons and Defective Contextual Memory in PC3/Tis21 Knockout Mice

(2009) Stefano Farioli-Vecchioli et al.   PLoS One

B Cell Translocation Gene 2 Enhances Susceptibility of HeLa Cells to Doxorubicin-induced Oxidative Damage

(2008) Young-Bin Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TIS21/BTG2Negatively Regulates Estradiol-Stimulated Expansion of Hematopoietic Stem Cells by Derepressing Akt Phosphorylation and Inhibiting mTOR Signal Transduction

(2008) Bong Cho Kim et al.   STEM CELLS