Design of experiments for development and optimization of a liquid chromatography coupled to tandem mass spectrometry bioanalytical assay

After another decade: LC–MS/MS became routine in clinical diagnostics

(2020) Christoph Seger et al.   CLINICAL BIOCHEMISTRY

Optimization of Ultra-High-Performance Liquid Chromatography-Electrospray Ionization-Mass Spectrometry Detection of Glutamine-FMOC Ad-Hoc Derivative by Central Composite Design

(2020) Khaggeswar Bheemanapally et al.   Scientific Reports

Comparing ultrafiltration and equilibrium dialysis to measure unbound plasma dolutegravir concentrations based on a design of experiment approach

(2020) David Metsu et al.   Scientific Reports

Comparison of the effect of allopurinol and febuxostat on urinary 2,8-dihydroxyadenine excretion in patients with Adenine phosphoribosyltransferase deficiency (APRTd): A clinical trial

(2018) Vidar O. Edvardsson et al.   European Journal of Internal Medicine

Design of Experiments in metabolomics-related studies: An overview

(2018) Julia Jacyna et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Robustness evaluation in analytical methods optimized using experimental designs

(2017) Sergio L.C. Ferreira et al.   MICROCHEMICAL JOURNAL

Optimization of Electrospray Ionization by Statistical Design of Experiments and Response Surface Methodology: Protein–Ligand Equilibrium Dissociation Constant Determinations

(2016) Liliana Pedro et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments

(2016) Elizabeth S. Hecht et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Comprehensive optimization of LC–MS metabolomics methods using design of experiments (COLMeD)

(2016) Seth D. Rhoades et al.   Metabolomics

Chemometric optimization and validation of a novel dispersive liquid–liquid microextraction–HPLC method for gliclazide, glibenclamide and glimepiride quantitation in serum samples

(2016) Celina M. Monzón et al.   MICROCHEMICAL JOURNAL

Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea

(2013) György Székely et al.   Drug Testing and Analysis

Experimental design in chromatography: A tutorial review

(2012) D. Brynn Hibbert   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Application of a design of experiment approach in the development of a sensitive bioanalytical assay in human plasma

(2012) Michelle L. Dawes et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Design of experiments as a tool for LC–MS/MS method development for the trace analysis of the potentially genotoxic 4-dimethylaminopyridine impurity in glucocorticoids

(2012) Gy. Székely et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Experimental designs and their recent advances in set-up, data interpretation, and analytical applications

(2011) Bieke Dejaegher et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Optimization of the simultaneous determination of imatinib and its major metabolite, CGP74588, in human plasma by a rapid HPLC method using D-optimal experimental design

(2011) Ali-Akbar Golabchifar et al.   TALANTA

Development and Validation of LC-MS/MS Method for the Quantification of Oxcarbazepine in Human Plasma Using an Experimental Design

(2008) Gedela Srinubabu et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Quantification of Methylmalonic Acid in Human Plasma with Hydrophilic Interaction Liquid Chromatography Separation and Mass Spectrometric Detection

(2008) H.-A. Lakso et al.   CLINICAL CHEMISTRY