Microbiota restoration for recurrent Clostridioides difficile : Getting one step closer every day!

Long-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection

(2021) Srishti Saha et al.   GASTROENTEROLOGY

Therapies to modulate gut microbiota: Past, present and future

(2020) Akshita Gupta et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Fecal Microbiota Transplantation for Recurrent Clostridioides difficile infection

(2020) Sahil Khanna et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

SER-109, an Investigational Microbiome Drug to Reduce Recurrence after Clostridioides difficile infection: Lessons Learned from a Phase 2 Trial

(2020) Barbara H McGovern et al.   CLINICAL INFECTIOUS DISEASES

Fecal microbiota transplantation for treatment of patients with recurrent Clostridioides difficile infection

(2020) Elida Voth et al.   Expert Review of Anti-Infective Therapy

Update on Treatment of Clostridioides difficile Infection

(2020) Janice M. Cho et al.   MAYO CLINIC PROCEEDINGS

Trends in U.S. Burden of Clostridioides difficile Infection and Outcomes

(2020) Alice Y. Guh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Predictors and Management of Failed Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection

(2020) Raseen Tariq et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

The Integrative Human microbiome project: a mile stone in the understanding of the gut microbiome

(2020) Elida Voth et al.   Expert Review of Gastroenterology & Hepatology

Durability Of Response To Fecal Microbiota Transplantation After Exposure to Risk Factors for Recurrence In Patients With Clostridioides difficile Infection

(2020) Srishti Saha et al.   CLINICAL INFECTIOUS DISEASES

RBX7455, a Room Temperature-Stable, Orally-Administered Investigational Live Biotherapeutic, is Safe, Effective, and Shifts Patients’ Microbiomes in a Phase 1 Study for Recurrent Clostridioides difficile Infections

(2020) Sahil Khanna et al.   CLINICAL INFECTIOUS DISEASES

Fecal Microbiota Transplantation: Tales of Caution

(2020) Sahil Khanna et al.   CLINICAL INFECTIOUS DISEASES

Shiga toxin-producing E. coli transmission via fecal microbiota transplant

(2020) Caroline Zellmer et al.   CLINICAL INFECTIOUS DISEASES

Fecal Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry

(2020) Colleen R. Kelly et al.   GASTROENTEROLOGY

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

(2019) Massimo Sartelli et al.   World Journal of Emergency Surgery

Mo1955 – Ve303, a Live Biotherapeutic Product for Prevention of Recurrent Clostridioides Difficile (C. Difficile) Infection. Preliminary Results of a Phase 1, Open-Label Healthy Volunteers Study of Oral Ve303 After Vancomycin

(2019) Dmitri Bobilev et al.   GASTROENTEROLOGY

A network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in recurrent Clostridium difficile infection

(2019) Theodore Rokkas et al.   United European Gastroenterology Journal

Donor Screening for Fecal Microbiota Transplantation

(2019) Zain Kassam et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant

(2019) Zachariah DeFilipp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of Fecal Microbiota Transplantation for Recurrent C. Difficile Infection in Inflammatory Bowel Disease

(2019) Raseen Tariq et al.   INFLAMMATORY BOWEL DISEASES

Results From a Randomized, Placebo-Controlled Clinical Trial of a RBX2660—A Microbiota-Based Drug for the Prevention of Recurrent Clostridium difficile Infection

(2018) Erik R Dubberke et al.   CLINICAL INFECTIOUS DISEASES

Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Patients at Increased Risk for Recurrence

(2018) Dale N Gerding et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

(2018) L Clifford McDonald et al.   CLINICAL INFECTIOUS DISEASES

Evaluation of 4 molecular assays as part of a 2-step algorithm for the detection of Clostridium difficile in stool specimens

(2018) Adam J. Caulfield et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

What do we know about the diagnostics, treatment and epidemiology of Clostridioides ( Clostridium ) difficile infection in Europe?

(2018) Elisabeth Nagy   JOURNAL OF INFECTION AND CHEMOTHERAPY

Low Cure Rates in Controlled Trials of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection: A Systematic Review and Meta-Analysis

(2018) Raseen Tariq et al.   CLINICAL INFECTIOUS DISEASES

Diagnosis and Treatment of Clostridium difficile Infection

(2018) Arjun Gupta et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial

(2018) Zhi-Dong Jiang et al.   PLoS One

Fecal Microbiota Transplantation

(2017) Arjun Gupta et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of Oral Capsule– vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection

(2017) Dina Kao et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study

(2017) Richard J Vickers et al.   LANCET INFECTIOUS DISEASES

Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection

(2017) Mark H. Wilcox et al.   NEW ENGLAND JOURNAL OF MEDICINE

The incidence and outcomes from Clostridium difficile infection in hospitalized adults with inflammatory bowel disease

(2017) George Saffouri et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Association of Gastric Acid Suppression With Recurrent Clostridium difficile Infection

(2017) Raseen Tariq et al.   JAMA Internal Medicine

Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease

(2017) Sahil Khanna et al.   Microbiome

RBX2660 is Safe, Superior to Antibiotic-Treated Controls for Preventing Recurrent Clostridium difficile, and May Rehabilitate Patient Microbiomes: Open Label Trial Results

(2017) Robert Orenstein et al.   Open Forum Infectious Diseases

High risk of post-infectious irritable bowel syndrome in patients withClostridium difficileinfection

(2016) A. Wadhwa et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

RecurrentClostridium difficileinfection associates with distinct bile acid and microbiome profiles

(2016) J. R. Allegretti et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Predictors of Early Failure After Fecal Microbiota Transplantation for the Therapy of Clostridium Difficile Infection: A Multicenter Study

(2016) Monika Fischer et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection

(2016) Colleen R. Kelly et al.   ANNALS OF INTERNAL MEDICINE

Inflammatory Bowel Disease Affects the Outcome of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

(2016) Alexander Khoruts et al.   Clinical Gastroenterology and Hepatology

Oral Vancomycin Followed by Fecal Transplantation Versus Tapering Oral Vancomycin Treatment for RecurrentClostridium difficileInfection: An Open-Label, Randomized Controlled Trial

(2016) Susy S. Hota et al.   CLINICAL INFECTIOUS DISEASES

Repeat Clostridium difficile Testing

(2016) Arjun Gupta et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With RecurrentClostridium difficileInfection

(2016) Christine H. Lee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Donor Screening Experience for Fecal Microbiota Transplantation in Patients With Recurrent C. difficile Infection

(2016) Raseen Tariq et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

A Novel Microbiome Therapeutic Increases Gut Microbial Diversity and Prevents RecurrentClostridium difficileInfection

(2016) Sahil Khanna et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical implications of antibiotic impact on gastrointestinal microbiota andClostridium difficileinfection

(2016) Sahil Khanna et al.   Expert Review of Gastroenterology & Hepatology

Systematic Review: Adverse Events of Fecal Microbiota Transplantation

(2016) Sinan Wang et al.   PLoS One

Safety and Durability of RBX2660 (Microbiota Suspension) for RecurrentClostridium difficileInfection: Results of the PUNCH CD Study

(2015) Robert Orenstein et al.   CLINICAL INFECTIOUS DISEASES

Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study

(2014) Ilan Youngster et al.   CLINICAL INFECTIOUS DISEASES

Oral, Capsulized, Frozen Fecal Microbiota Transplantation for RelapsingClostridium difficileInfection

(2014) Ilan Youngster et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

European Society of Clinical Microbiology and Infectious Diseases: Update of the Treatment Guidance Document for Clostridium difficile Infection

(2013) S.B. Debast et al.   CLINICAL MICROBIOLOGY AND INFECTION

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Standardized Frozen Preparation for Transplantation of Fecal Microbiota for Recurrent Clostridium difficile Infection

(2012) Matthew J Hamilton et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Long-Term Follow-Up of Colonoscopic Fecal Microbiota Transplant for Recurrent Clostridium difficile Infection

(2012) Lawrence J Brandt et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Fidaxomicin Preserves the Intestinal Microbiome During and After Treatment of Clostridium difficile Infection (CDI) and Reduces Both Toxin Reexpression and Recurrence of CDI

(2012) T. J. Louie et al.   CLINICAL INFECTIOUS DISEASES

The Epidemiology of Community-Acquired Clostridium difficile Infection: A Population-Based Study

(2011) Sahil Khanna et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The growing incidence and severity ofClostridium difficileinfection in inpatient and outpatient settings

(2010) Sahil Khanna et al.   Expert Review of Gastroenterology & Hepatology

Decreased Diversity of the Fecal Microbiome in RecurrentClostridium difficile–Associated Diarrhea

(2008) Ju Young Chang et al.   JOURNAL OF INFECTIOUS DISEASES