Article
Multidisciplinary Sciences
Yue Huang, Yingwen Hu, Unman Chan, Pengyu Lai, Yueting Sun, Jun Dai, Xin Cheng, Xuesong Yang
Summary: This study explored the feasibility and acceptance of using virtual reality technology to train dental students in dental implantology. The results showed that virtual reality technology was helpful in improving students' implant skills and was well received by the participants.
Article
Health Care Sciences & Services
Hawazen A. Radwan, Alla T. Alsharif, Maha T. Alsharif, Mohammed R. Aloufi, Bassam S. Alshammari
Summary: This study aimed to assess the characteristics and professional aspects of practicing dentists in Saudi Arabia that influence users to adopt Digital Technologies in Dentistry (DTD). It also identified dentists' perceived barriers and challenges, as well as potential developments towards implementing DTDs. The study used a validated questionnaire and a snowball sampling technique to include dentists from all dental specialties currently working in Saudi Arabia.
Review
Chemistry, Multidisciplinary
Eisha Imran, Necdet Adanir, Zohaib Khurshid
Summary: The use of haptic and virtual reality technologies in dental education has revolutionized teaching methods by allowing students to interact with digital simulations to learn treatment skills and gain confidence. This approach also aids in material conservation, teacher-controlled student assessments, and creating a safe learning environment for participants.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Theerasak Nakornnoi, Chanchawan Chantakao, Nutchanon Luangaram, Thapakorn Janbamrung, Teetouch Thitasomakul, Kawin Sipiyaruk
Summary: This study investigated the perceptions of orthodontic residents towards the importance and confidence of dental technologies. It found that intraoral scanners, CBCT, digital treatment planning software, lab-produced aligners, and digital modeling software were considered necessary for clinical practice and should be included in orthodontic postgraduate programs.
Article
Multidisciplinary Sciences
Pedro Rodrigues, Francisco Nicolau, Martim Norte, Ezequiel Zorzal, Joao Botelho, Vanessa Machado, Luis Proenca, Ricardo Alves, Carlos Zagalo, Daniel Simoes Lopes, Jose Joao Mendes
Summary: This study tested and evaluated the second installment of DENTIFY, a virtual reality haptic simulator for Operative Dentistry (OD), on preclinical dental students. The results showed that drill time decreased steadily with increased use of the DENTIFY prototype, and participants with certain characteristics demonstrated higher performance. The correlation between participants' performance and self-assessment evaluation suggested that DENTIFY improved their perception of manual force applied.
SCIENTIFIC REPORTS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Xinyi Yan, Yongyang Yan, Mengyao Cao, Wenxuan Xie, Siobhan O'Connor, Jung Jae Lee, Mu-Hsing Ho
Summary: This study analyzed the effectiveness of virtual reality (VR) distraction intervention in managing dental anxiety in paediatric patients. Results from 12 randomized controlled trials showed that VR distraction interventions were effective in reducing dental anxiety in paediatric patients. However, publication bias may weaken the evidence of VR in managing dental anxiety.
JOURNAL OF DENTISTRY
(2023)
Article
Chemistry, Multidisciplinary
Reham Alabduljabbar, Maha Almutawa, Renad Alkathiri, Abeer Alqahtani, Hala Alshamlan
Summary: Dental anxiety in children is a common issue that can be managed through the use of augmented reality and virtual reality technologies. The study found that using virtual reality technology significantly reduced children's dental anxiety levels, which is beneficial for patients, parents, and dental professionals.
APPLIED SCIENCES-BASEL
(2023)
Article
Computer Science, Interdisciplinary Applications
James Calvert, Margee Hume
Summary: Our research investigates the use of narrative immersive virtual reality (IVR) in a classroom setting as pre-training material. The effectiveness of using narrative IVR in education is still limited. To address this, our study examines the cognitive and affective benefits of a narrative-based IVR experience called Thin Ice VR for students studying polar history and climate change. Results showed a significant increase in knowledge transfer when narrative IVR was used as pre-training material. However, its impact on knowledge acquisition, engagement, and motivation was minimal. The immersive narrative experience in IVR can elicit emotional reactions and is an effective medium for storytelling in classrooms.
Article
Chemistry, Multidisciplinary
Mykolas Akulauskas, Karolis Butkus, Vygandas Rutkunas, Tomas Blazauskas, Darius Jegelevicius
Summary: Augmented reality headsets can display real-time guidance instructions in dental surgery, improving patient-friendliness and efficiency.
APPLIED SCIENCES-BASEL
(2023)
Article
Education & Educational Research
Olia E. Tsivitanidou, Yiannis Georgiou, Andri Ioannou
Summary: The study explored the impact of integrating immersive virtual reality (VR) in science classrooms on high school students' conceptual learning gains and their perceptions of the experience. Results showed a significant relationship between students' attitudes and learning outcomes, with students who had higher attitudes towards science and digital technologies performing better in the learning experience.
JOURNAL OF SCIENCE EDUCATION AND TECHNOLOGY
(2021)
Review
Nursing
Jeeyae Choi, C. Elise Thompson, Jeungok Choi, Colette B. Waddill, Soyoung Choi
Summary: This review analyzed the effectiveness and barriers of using immersive virtual reality in nursing education. The results showed that immersive VR can improve learning, cognitive, and psychomotor performance, and most participants preferred using it in education. However, there were barriers related to technological hardware and software that need to be addressed.
Article
Education & Educational Research
Iuliia Sergeevna Khukalenko, Regina Kaplan-Rakowski, Yunjo An, Vera Dmitrievna Iushina
Summary: High-immersion virtual reality technology is increasingly popular in education for its potential to engage and motivate learners. This paper reports the results of a survey on teachers' attitudes toward the use of VR in education, showing that teachers have moderately positive perceptions of VR use and that lower levels of VR integration are associated with more traditional teaching approaches.
EDUCATION AND INFORMATION TECHNOLOGIES
(2022)
Article
Chemistry, Multidisciplinary
Raidan Ba-Hattab, Dilek Helvacioglu-Yigit, Lamyia Anweigi, Tayeb Alhadeethi, Mahwish Raja, Sundus Atique, Hanin Daas, Rebecca Glanville, Berkan Celikten, Kaan Orhan, Kamran Ali
Summary: We evaluated the impact of Virtual Reality Dental Simulators (VRDS) on preclinical training in endodontics for undergraduate dental students. The participants reported positive experiences with VRDS and found it helpful in improving their fine motor skills. VRDS training was perceived to be similar to natural and acrylic teeth by the majority of participants.
APPLIED SCIENCES-BASEL
(2023)
Article
Education & Educational Research
Alaa Daud, Manal Matoug-Elwerfelli, Hanin Daas, Daniel Zahra, Kamran Ali
Summary: This study aimed to evaluate the impact of Virtual Reality haptic simulation (VRHS) on restorative dentistry learning. The findings suggest that VRHS can enhance manual dexterity in dental students, but improvements to hardware and software are needed, and integration into the curriculum should be carefully planned to optimize benefits.
BMC MEDICAL EDUCATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Diana Xavier de Barros Padilha, Nelio Jorge Veiga, Anna Carolina Volpi Mello-Moura, Patricia Nunes Correia
Summary: Virtual reality (VR) has emerged as an innovative tool in pediatric dentistry, effectively managing anxiety and pain during dental procedures, providing a positive treatment experience for young patients.
Article
Pharmacology & Pharmacy
Xinyu Peng, Qi Han, Xuedong Zhou, Yanyan Chen, Xiaoyu Huang, Xiao Guo, Ruiting Peng, Haohao Wang, Xian Peng, Lei Cheng
Summary: Dental caries is a preventable infectious disease caused by interactions between oral bacteria and dietary sugars. pH-sensitive drug delivery systems have become innovative materials for caries prevention. In this study, a pH-sensitive carrier (poly(DMAEMA-co-HEMA)) was used to synthesize a nanomaterial loaded with chlorhexidine (p(DH)@CHX), which exhibited good pH sensitivity and sustained release of CHX in an acidic environment. It showed lower cytotoxicity than free CHX and had the same antibacterial effects on biofilms. In addition, it had the potential to alter oral microbiota composition and reduce caries risk.
Review
Cell Biology
Haoran Chen, Yujia Cui, Demao Zhang, Jing Xie, Xuedong Zhou
Summary: This review systematically summarizes studies published in the past 5 years that assess the relationship between FGF-8 and chondrocytes, revealing the regulatory role of FGF-8 in chondrocyte proliferation, differentiation, survival, and migration. Based on the analysis of existing research results, a therapeutic regimen targeting FGF-8 is proposed to explore the possibility of treating chondrocyte-related diseases.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
R. T. Peng, Y. Sun, X. D. Zhou, S. Y. Liu, Q. Han, L. Cheng, X. Peng
Summary: This study found that Treponema denticola can invade oral squamous cell carcinoma (OSCC) cells and directly promote cell proliferation, regulate the cell cycle, and inhibit apoptosis. It also promotes OSCC tumor growth in mice and upregulates Ki67 expression. The mechanism involves activation of the TGF-beta pathway. Treponema denticola may play an important role in the development of OSCC.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Liu Wang, Yao Song, Xiaowei Yi, Chenzhou Wu, Qiang Guo, Xuedong Zhou, Dongzhe Song, Lan Zhang, Dingming Huang
Summary: This study found that SEMA7A plays a proinflammatory and bone destructive role in periapical lesions, and this proinflammatory function may be mediated through the AKT signaling pathway.
JOURNAL OF ENDODONTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Weizhe Xu, Qian Lu, Moyuan Qu, Rong Fan, Sha Leng, Liu Wang, Linyi Liu, Fan Yang, Xuedong Zhou, Dingming Huang, Lan Zhang
Summary: The study revealed that Wnt4 inhibits the IKK-NF-kappa B signaling pathway and activates the ROCK signaling pathway to suppress osteoclast formation and promote bone regeneration in occlusal trauma and periodontitis-bearing mice. These findings suggest the potential therapeutic efficacy of Wnt4 in treating these conditions.
JOURNAL OF PERIODONTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Liu Wang, Xiangfen Li, Yao Song, Lan Zhang, Ling Ye, Xuedong Zhou, Dongzhe Song, Dingming Huang
Summary: This study explored the effect of BMP9 on the osteogenic differentiation of inflammatory periodontal ligament stem cells (PDLSCs). The results showed that BMP9 promoted osteogenic differentiation of PDLSCs, but also upregulated the expression of inflammatory markers. NELL1 played an important role in this process by activating the MAPK/p38/ERK signaling pathway, reducing the expression of inflammatory genes induced by BMP9, and enhancing the osteogenic effect of the cells.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Microbiology
Zong Yawen, Cheng Xiangyun, Liao Binyou, Ye Xingchen, Liu Taiping, Zhou Xuedong, Li Jiyao, Cheng Lei, Xu Wenyue, Ren Biao
Summary: Our study revealed a complex and important relationship between intestinal microbiota and host immunity during Plasmodium infection, highlighting the crucial regulatory role of intestinal microbiome in modulating host immunity against the parasite.
MICROBIOLOGICAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yujia Cui, Jing Xie, Linyi Cai, Demao Zhang, Jianxun Sun, Xuedong Zhou
Summary: This study suggests that berberine repairs bone destruction caused by apical periodontics by reducing osteoclast activity, promoting osteoblast differentiation, and inhibiting inflammatory response.
Review
Dentistry, Oral Surgery & Medicine
Xian Peng, Lei Cheng, Yong You, Chengwei Tang, Biao Ren, Yuqing Li, Xin Xu, Xuedong Zhou
Summary: Oral bacteria directly influence dental caries and periodontal diseases, and the dynamic oral microbiota reflects immune and metabolic information and status through communication between the oral cavity and systemic organs. The oral cavity acts as an important interaction window between the human body and the environment, and the microbial composition in different sites is regulated by complex signaling, hosts, and external environmental factors.
INTERNATIONAL JOURNAL OF ORAL SCIENCE
(2022)
Review
Dentistry, Oral Surgery & Medicine
Lei Cheng, Lu Zhang, Lin Yue, Junqi Ling, Mingwen Fan, Deqin Yang, Zhengwei Huang, Yumei Niu, Jianguo Liu, Jin Zhao, Yanhong Li, Bin Guo, Zhi Chen, Xuedong Zhou
Summary: Dental caries is a chronic oral disease that poses a significant threat to human health. Despite efforts by dentists and researchers, the prevalence of dental caries remains high. Establishing a clinical difficulty assessment system for caries prevention and management based on diagnosis and classification is crucial. Dentists should conduct oral examinations and create dental records during each visit. Personalized treatment plans, based on caries risk assessment and lesion activity, are necessary to restore oral microecological balance, control caries progression, and restore the structure and function of the affected teeth. Follow-up visits should be conducted based on personalized caries management. This expert consensus focuses on caries risk assessment, treatment difficulty assessment, and dental caries treatment plans, which are essential components of caries management throughout the life cycle.
INTERNATIONAL JOURNAL OF ORAL SCIENCE
(2022)
Review
Immunology
Hao Dong, Jiaxin Liu, Jianhui Zhu, Zhiyan Zhou, Marco Tizzano, Xian Peng, Xuedong Zhou, Xin Xu, Xin Zheng
Summary: Taste receptors play a role in the interaction between oral microbiota and the host, affecting the occurrence and development of oral diseases.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Yongwang Lin, Tao Gong, Qizhao Ma, Meiling Jing, Ting Zheng, Jiangchuan Yan, Jiamin Chen, Yangyang Pan, Qun Sun, Xuedong Zhou, Yuqing Li
Summary: Nicotinamide (NAM) inhibits the growth and acid production ability of Streptococcus mutans (S. mutans), as well as reducing its biofilm and exopolysaccharides (EPS) production. NAM exerts its inhibitory effects by modulating gene expression. In a rat caries model, NAM significantly reduces the incidence and severity of caries.
JOURNAL OF ORAL MICROBIOLOGY
(2022)
Article
Microbiology
Yandi Chen, Bina Yang, Lei Cheng, Hockin H. K. Xu, Hao Li, Yuyao Huang, Qiong Zhang, Xuedong Zhou, Jingou Liang, Jing Zou
Summary: This study developed novel modified giomers by incorporating antibacterial QAMs to inhibit cariogenic biofilms, with demonstrated anti-caries effects in a rat model.
Article
Dentistry, Oral Surgery & Medicine
Menglin Fan, Meng Li, Yingming Yang, Michael D. Weir, Yifang Liu, Xuedong Zhou, Kunneng Liang, Jiyao Li, Hockin H. K. Xu
Summary: This study aimed to assess the remineralization efficiency of adhesive with DMAHDM and NACP on initial caries lesion of biofilm-coated enamel. The results showed that this adhesive can effectively promote enamel remineralization, thus protecting the bonding interface and inhibiting secondary caries.
Article
Microbiology
Yangyang Shi, Jingou Liang, Xuedong Zhou, Biao Ren, Haohao Wang, Qi Han, Hao Li, Lei Cheng
Summary: The study found that DMAEM@RA had a pH-responsive antimicrobial effect on Streptococcus mutans and Candida albicans dual-species biofilms, preventing secondary caries and attenuating cariogenic virulence.
