CES1P1 variant −816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

(2015) EK Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clopidogrel Bioactivation and Risk of Bleeding in Patients Cotreated With Angiotensin-Converting Enzyme Inhibitors After Myocardial Infarction: A Proof-of-Concept Study

(2014) K E Kristensen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CES1A −816C as a Genetic Marker to Predict Greater Platelet Clopidogrel Response in Patients with Percutaneous Coronary Intervention

(2013) Jian-Jun Zou et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Dose-Dependent Antihypertensive Efficacy and Tolerability of Perindopril in a Large, Observational, 12-Week, General Practice-Based Study

(2011) George Tsoukas et al.   American Journal of Cardiovascular Drugs

Surge in Expression of Carboxylesterase 1 During the Post-neonatal Stage Enables a Rapid Gain of the Capacity to Activate the Anti-influenza Prodrug Oseltamivir

(2011) Deshi Shi et al.   JOURNAL OF INFECTIOUS DISEASES

Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

(2010) Kimie Sai et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Antihypertensive efficacy and safety of olmesartan medoxomil and ramipril in elderly patients with mild to moderate essential hypertension: the ESPORT study

(2010) Ettore Malacco et al.   JOURNAL OF HYPERTENSION

Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: Potential sources of metabolic drug interactions

(2010) Hao-Jie Zhu et al.   TOXICOLOGY

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril

(2009) Hao-Jie Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Antihypertensive Efficacy of Perindopril 5–10 mg/day in Primary Health Care

(2009) Dan-Dominic Ionescu   CLINICAL DRUG INVESTIGATION

Age- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human Liver

(2009) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Two CES1 Gene Mutations Lead to Dysfunctional Carboxylesterase 1 Activity in Man: Clinical Significance and Molecular Basis

(2008) Hao-Jie Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional polymorphisms in carboxylesterase1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites

(2008) Mika Yoshimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin

(2008) Dongfang Yang et al.   BIOCHEMICAL PHARMACOLOGY

Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants

(2008) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes

(2008) Tatsuki Fukami et al.   Pharmacogenetics and Genomics