Article
Dentistry, Oral Surgery & Medicine
Philipp Sahrmann, Sophie Winkler, Andrea Gubler, Thomas Attin
Summary: The study evaluated changes of implant surfaces with different roughness after instrumentation with ultrasonic-driven scaler tips of different materials. Results showed that all tips except resin left extensive residuals on the surfaces, with the least change resulting from resin or carbon tips on machined surfaces.
Article
Dentistry, Oral Surgery & Medicine
Na Zhou, Haohao Huang, Hui Liu, Qiang Li, Guangwen Yang, Yu Zhang, Meng Ding, Heng Dong, Yongbin Mou
Summary: Analysis showed significant differences in bacterial structures between NH and PM implant groups, with higher relative abundance of Actinomyces and Streptococcus in NH samples. Genera Fusobacterium and Prevotella were identified as potential biomarkers for peri-implant mucositis. Moreover, gram-negative anaerobic bacteria, including Porphyromonas and Prevotella, were more prevalent in samples from patients with periodontitis history, indicating higher risk for peri-implant mucositis.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Immunology
Cong He, Yong Xie, Yin Zhu, Kun Zhuang, Lijuan Huo, Yong Yu, Qiang Guo, Xu Shu, Zhijuan Xiong, Zhenyu Zhang, Bin Lyu, Nonghua Lu
Summary: This study not only demonstrated the beneficial effect of probiotics implementation on side events during H. pylori eradication but also provided a comprehensive profile of microbiome alterations along the gastrointestinal tract that is modulated by probiotics.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yohei Jinno, Michele Stocchero, Marco Toia, Evaggelia Papia, Marianne Ahmad, Jonas Peter Becktor
Summary: This study aimed to evaluate the effects of saliva contamination during implant placement with different surface characteristics on osseointegration in native and augmented bone areas. The results showed that saliva contamination had a negative impact on bone-implant contact, especially in augmented areas. Implants with a moderately rough surface exhibited better bone-implant contact compared to those with a machined surface.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
R. Raksakmanut, P. Thanyasrisung, S. Sritangsirikul, K. Kitsahawong, A. L. Seminario, W. Pitiphat, O. Matangkasombut
Summary: Dental caries, the most common chronic disease in children, has negative effects on their health, development, and well-being. Early preventive interventions are crucial, but there is still a lack of accurate caries risk predictors for infants before caries onset.
JOURNAL OF DENTAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Marcel F. Kunrath, Andre Correia, Eduardo R. Teixeira, Roberto Hubler, Christer Dahlin
Summary: This pilot study investigated the surface alterations caused on hydrophilic nanotubular surfaces after early human saliva interaction. The results showed that saliva interaction did not significantly affect morphological characteristics, roughness, and chemical composition, but altered the hydrophilicity. Without wet storage, saliva contamination significantly reduced the cellular viability of pre-osteoblasts. Therefore, saliva-controlled sites or modified-package methods with wet storage are recommended for oral application of hydrophilic surfaces.
Review
Chemistry, Physical
Georgina Gonzalez-Valls, Elisabet Roca-Millan, Juan Manuel Cespedes-Sanchez, Beatriz Gonzalez-Navarro, Aina Torrejon-Moya, Jose Lopez-Lopez
Summary: This study systematically evaluated the literature on narrow dental implants from 2010 to 2021, showing that small diameter implants have favorable survival and success rates, as well as marginal bone loss within 36 months.
Review
Endocrinology & Metabolism
G. Dipalma, A. D. Inchingolo, F. Inchingolo, I. A. Charitos, M. Di Cosola, A. P. Cazzolla
Summary: This paper discusses the biochemical interactions between teeth and the oral environment during the caries process, including physico-chemical reactions, theoretical basis for prevention and treatment, 'demineralization' and 'remineralization', the role of microbiota, as well as the mechanisms of carious lesion development, healing, and repair.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2021)
Article
Engineering, Mechanical
Sudip Saha, K. Uday Venkat Kiran, Xin Zhang, Xiaodong Hou, Sougata Roy
Summary: The research aimed to investigate the effectiveness of using wrought cobalt-chromium (Co-Cr) alloy as a dental implant through corrosion, immersion, and tribological behavior analyses. The study found that acidic saliva solutions had higher corrosive behavior than neutral and basic solutions. The wear behavior of the Co-Cr alloy was influenced by the generation of oxide layers and the presence of phosphorus and calcium in saliva.
Article
Medicine, General & Internal
Haixia Xing, Hongwei Liu, Jie Pan
Summary: This study characterized the saliva microbiota of Candida carriage Sjogren's syndrome patients using high-throughput sequencing. The results showed significant microbial dysbiosis in SS patients, which differed from oral candidiasis and healthy patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Andres Stricker, Thomas Bergfeldt, Tobias Fretwurst, Owen Addison, Rainer Schmelzeisen, Rene Rothweiler, Katja Nelson, Christian Gross
Summary: The study found exogenous metal contaminants and other impurities in commercial titanium dental implants, which may provoke immunological reactions despite conforming to standard compositions. Further investigation into the clinical relevance of these findings and discussion on the adjustment of industry standards are warranted.
Review
Microbiology
Jessica Alves Cena, Leticia Goncalves Reis, Ana Karolina Almeida de Lima, Camilla Pedrosa Vieira Lima, Cristine Miron Stefani, Naile Dame-Teixeira
Summary: This systematic review compared the salivary microbiota of adults with type 2 diabetes mellitus (T2D) to those without T2D, focusing on acid-associated bacteria. It found that diabetics had a higher abundance of acidogenic and aciduric bacteria, as well as enrichment of specific acid-associated genera.
Article
Microbiology
Weihua Shi, Jing Tian, He Xu, Man Qin
Summary: Epidemiological studies have found a correlation between caries in deciduous molars and permanent molars. This study investigated the association between caries subtypes in deciduous molars and first permanent molars, as well as the microbiota involved in different subtypes. The results suggest that classification of deciduous molar caries based on the microbiota could predict the risk of caries in adjacent first permanent molars.
Article
Chemistry, Physical
Nerea Arlucea, Aritza Brizuela-Velasco, Markel Dieguez-Pereira, Miquel Punset, Meritxell Molmeneu, Fernando Sanchez Lasheras, Hector deLlanos-Lanchares, Angel Alvarez-Arenal
Summary: This experimental trial compared the stability and micro-movement values of titanium and zirconia dental implants under load. The results showed that zirconia implants have higher stability values, but there were no significant differences in micro-movement values when load was applied between the two types.
Article
Biochemistry & Molecular Biology
Miguel de Araujo Nobre, Carlos Moura Guedes, Ricardo Almeida, Antonio Silva, Nuno Sereno
Summary: This study demonstrates that PEEK-acrylic resin implant-supported full-arch prostheses have high prosthetic and implant survival rates, low marginal bone loss, and low rates of biological and prosthetic complications.
Letter
Dentistry, Oral Surgery & Medicine
A. Meethil, S. Saraswat, P. P. Chaudhary, S. Dabdoub, P. Kumar
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Helvis E. S. Paz, Mabelle F. Monteiro, Camila S. Stolf, Khaled Altabtbaei, Marcio Z. Casati, Renato C. Casarin, Purnima S. Kumar
Summary: This study evaluated the taxonomic and predicted functional content of the subgingival microbiome of young patients with Grade C periodontitis under supportive periodontal therapy. The results showed that despite clinical improvements, the microbiome of these patients remained different from individuals without a history of disease.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sukirth M. Ganesan, Shareef M. Dabdoub, Haikady N. Nagaraja, Angelo J. Mariotti, Christopher W. Ludden, Purnima S. Kumar
Summary: This study revealed that there is an active transcriptional activity of the peri-implant microbiome surrounding healthy implants. In disease conditions, an upregulation of microbial genes correlated with human genes, suggesting a potential role of commensals in maintaining epithelial integrity.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Endocrinology & Metabolism
Jie Liu, Keiichiro Watanabe, Shareef M. Dabdoub, Beth S. Lee, Do-Gyoon Kim
Summary: One-third of postmenopausal women experience osteoporotic bone fractures, but jaw bone fractures are rare. The mechanisms behind the differences between jaw bone and limb bone during postmenopause are largely unknown. This study examined the effects of estrogen deficiency on bone quantity and quality, and found that mandibular bone marrow stem cells had greater differentiation capacity than femur bone marrow stem cells.
Review
Microbiology
Tabitha K. Peter, Miyuraj H. H. Withanage, Carissa L. Comnick, Chandler Pendleton, Shareef Dabdoub, Sukirth Ganesan, David Drake, Jeffrey Banas, Xian Jin Xie, Erliang Zeng
Summary: This study investigated the relationship between the human oral microbiome and oral squamous cell carcinoma, identifying microbial genera and functional pathways potentially associated with oral cancer, as well as highlighting gene abundance data that warrant further investigation. The study also addressed limitations related to data heterogeneity and proposed standardized data analytic practices to improve rigor and reproducibility in research.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Purnima S. Kumar
Article
Dentistry, Oral Surgery & Medicine
Aurelio Amorim Reis, Mabelle Freitas Monteiro, Gabriela Martin Bonilha, Luciana Saraiva, Cassia Araujo, Mauro Pedrine Santamaria, Marcio Zaffalon Casati, Purnima Kumar, Renato Correa Viana Casarin
Summary: The aim of this study was to evaluate microbial colonization in different dentition phases among individuals from 0 to 18 years old with a family history of periodontitis compared to descendants of periodontally healthy parents. The results showed that the parents' periodontal status significantly affected the microbiome composition of their offspring, and descendants with a family history of periodontitis exhibited different microbial diversity and a higher prevalence of periodontitis-associated species in the mixed and permanent dentition phases.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Sukirth M. M. Ganesan, Tabitha K. K. Peter, Miyuraj H. H. Withanage, Frank Boksa, Erliang Zeng, April Martinez, Shareef M. M. Dabdoub, Kunal Dingra, Yvonne Hernandez-Kapila
Summary: Three years into the COVID-19 pandemic, concerns about different variants, unknown long-term effects, and potential biological mechanisms have arisen. The role of the oral microbiome in COVID-19 research has been explored, showing disruptions and reduced diversity. Neisseria bacteria may play a key role.
PERIODONTOLOGY 2000
(2023)
Article
Biochemistry & Molecular Biology
Simon E. Roux, Antonio Pedro Camargo, Felipe H. Coutinho, Shareef M. Dabdoub, Bas E. Dutilh, Stephen Nayfach, Andrew Tritt
Summary: The extraordinary diversity of viruses infecting bacteria and archaea can be studied through metagenomics. However, metagenome-derived viral sequences lack key information about host association. We introduce iPHoP, a framework that integrates multiple methods to predict host taxonomy for a range of uncultivated viruses, while maintaining a low false discovery rate. Using a large dataset from the IMG/VR database, iPHoP shows promise in providing extensive host prediction for uncultivated viruses.
Article
Allergy
Prem Prashant Chaudhary, Ian A. Myles, Jordan Zeldin, Shareef Dabdoub, Varsha Deopujari, Rajiv Baveja, Robin Baker, Sarah Bengtson, Ashleigh Sutton, Shira Levy, Suchitra K. Hourigan
Summary: This study used metagenomic sequencing to analyze the skin microbiome of 72 infants over a period of 3 years and found that the microbiome of infants with atopic dermatitis (AD) differed from that of healthy individuals, which may be related to specific microbial taxa and metabolic pathways. The results suggest that AD may be caused by dysbiosis of the skin microbiome rather than being a secondary consequence of skin inflammation.
Article
Dentistry, Oral Surgery & Medicine
Khaled Sinjab, Shriya Sawant, Alice Ou, J. Christopher Fenno, Hom-Lay Wang, Purnima Kumar
Summary: This study aimed to investigate the impact of implant surface modifications on the peri-implant microbiome. The results showed that surface modifications did not significantly affect the microbiome of healthy implants, but had a significant impact on peri-implantitis (PI) implants. Furthermore, different surface modifications led to changes in the composition of bacterial species in healthy and PI implants.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Tamires Pereira Dutra, Mabelle Freitas Monteiro, Isabela Lima Franca-Grohmann, Renato Correa Viana Casarin, Marcio Zaffalon Casati, Karina Gonzalez Silverio Ruiz, Purnima S. Kumar, Enilson Antonio Sallum
Summary: This study compared individuals with a history of periodontitis to periodontally healthy subjects in terms of immunological and microbiological changes during experimental peri-implant mucositis and gingivitis. The results showed that different microbial shifts contribute to the onset and progression of inflammatory responses around teeth and implants, while the history of periodontal disease plays a role in modulating the immune response.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Correction
Dentistry, Oral Surgery & Medicine
A. P. Meethil, S. Saraswat, P. P. Chaudhary, S. M. Dabdoub, P. S. Kumar
JOURNAL OF DENTAL RESEARCH
(2022)