Article
Cardiac & Cardiovascular Systems
Malakh Shrestha, Dietmar Boethig, Heike Kruger, Tim Kaufeld, Andreas Martens, Axel Haverich, Erik Beckmann
Summary: This article presents a 25-year experience with valve-sparing aortic root replacement using a straight tube graft. The procedure was found to have low perioperative morbidity and mortality rates, and the short- and long-term results were excellent.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Tomislav Cvitkovic, Dmitry Bobylev, Alexander Horke, Murat Avsar, Philipp Beerbaum, Andreas Martens, Dietmar Boethig, Elena Petena, Marcel Gutberlet, Frerk Hinnerk Beyer, Frank Wacker, Serghei Cebotari, Axel Haverich, Jens Vogel-Claussen, Samir Sarikouch, Christoph Czerner
Summary: This study compares the hemodynamic parameters of long-valved decellularized aortic homografts and patients who underwent valve-sparing aortic root replacement with healthy controls. The results show that the hemodynamic parameters of decellularized long aortic homografts are similar to those of healthy controls and patients who underwent valve-sparing aortic root replacement 2.5 years postoperatively.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Erin M. Iannacone, Christopher Lau, Giovanni Soletti, Roberto Perezgrovas Olaria, Lamia Harik, Arnaldo Dimagli, Leonard N. Girardi
Summary: This article reviews the development and refinement of surgical techniques for aortic root surgery over the past 50 years, and summarizes the latest evidence on early and long-term outcomes. Additionally, brief descriptions are provided on the use of valve-sparing technique in various clinical settings, including high-risk patients with connective tissue disorders or concomitant dissection.
ANNALS OF CARDIOTHORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Erik Beckmann, Andreas Martens, Heike Krueger, Wilhelm Korte, Tim Kaufeld, Axel Haverich, Malakh Lal Shrestha
Summary: The retrospective study analyzed the outcomes of 29 adolescent patients aged 6 to 21 who underwent the David-I procedure, showing no early perioperative deaths but 14% late deaths and 17% aortic valve-related reoperations during long-term follow-up. Aortic valve-sparing root replacement in adolescents is associated with low perioperative risk.
THORACIC AND CARDIOVASCULAR SURGEON
(2021)
Article
Cardiac & Cardiovascular Systems
Yves d'Udekem, Eiri Kisamori, Shuta Ishigami, Igor E. Konstantinov
Summary: This study retrospectively analyzed 17 pediatric patients who underwent aortic valve-sparing procedures at the Royal Children's Hospital, Melbourne between 2006 and 2016. The results showed that aortic valve-sparing surgery is a feasible option for pediatric patients, although it requires a highly skilled surgeon.
ANNALS OF CARDIOTHORACIC SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Guala, Arturo Evangelista, Gisela Teixido-Tura, Lucia La Mura, Lydia Dux-Santoy, Aroa Ruiz-Munoz, Filipa Valente, Laura Galian-Gay, Laura Gutierrez, Teresa Gonzalez-Alujas, Ilaria Dentamaro, Kevin M. Johnson, Oliver Wieben, Augusto Sao Aviles, Ignacio Ferreira-Gonzalez, Jose F. Rodriguez-Palomares
Summary: The study found that the length of aortic valve fusion is related to aortic dilation and flow abnormalities in BAV patients, potentially providing a pathophysiological link to aortic dilation.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yihua Liu, Mohamed-Yassine Benzha, Maxime Hubert, Benjamin Perin, Giuseppe Lauria, Pan Dan, Elodie Phamisith, Soukaina Scadi, Nianguo Dong, Jean-Pierre Villemot, Juan-Pablo Maureira
Summary: Valve-sparing aortic root replacement can be safely performed in elderly patients with low early mortality and satisfactory long-term freedom from aortic valve-related and cardiovascular re-intervention. The study found a lower rate of valve-related reoperation and significant differences in prognosis between elderly and young patients, with lower survival rates in elderly patients.
HEART LUNG AND CIRCULATION
(2022)
Article
Cardiac & Cardiovascular Systems
Reilly D. Hobbs, Megan L. Schultz, Megan L. Loney, Sonaal Verma, Julia Xiong, Richard G. Ohye, Edward Bove, Ming-Sing Si
Summary: This study aimed to describe the experience of valve-sparing aortic root replacement in children with prior Ross procedures. Results showed that reimplantation offers better durability compared with the traditional remodeling procedure. Patients with moderate or severe postoperative neoaortic insufficiency were more likely to require subsequent valve replacement.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Bin Hou, Rui Zhao, De Wang, Wei Wang, Zhenhua Zhao, Xiaogang Sun, Xiangyang Qian, Cuntao Yu
Summary: This study demonstrated the safety and feasibility of valve-sparing root replacement via partial upper sternotomy in selected patients. Compared to complete sternotomy, the partial upper sternotomy group had lower blood loss, blood product consumption, and hospitalization expenses.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Article
Biology
Guido Nannini, Alessandro Caimi, Maria Chiara Palumbo, Simone Saitta, Leonard N. Girardi, Mario Gaudino, Mary J. Roman, Jonathan W. Weinsaft, Alberto Redaelli
Summary: The study demonstrates that after valve-sparing root replacement, there is an increase in velocity, distensibility, stress, and strain in the descending aorta, which may lead to adverse vessel remodeling. The fluid-structure interaction method is necessary to obtain reliable results on the wall distensibility and the impact of graft implantation on hemodynamics and biomechanics along the thoracic aorta.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Amine Mazine, Michael W. A. Chu, Ismail El-Hamamsy, Mark D. Peterson
Summary: This article reviews the contemporary evidence supporting valve-sparing aortic root replacement as the best option for patients with aortic root aneurysms and preservable aortic valves. It also discusses the technical variations and modern adjuncts of these operations that impact both short and long-term durability. The findings suggest that valve-sparing aortic root replacement provides excellent clinical outcomes and stable valve function for patients with aortic root aneurysms. Careful patient selection and understanding of the anatomical and physiological relationships are crucial for the success of this operation. Echocardiography plays a key role in determining the feasibility of valve-sparing root replacement.
CURRENT OPINION IN CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Shinichiro Oda, Satoshi Fujita, Hideki Tatewaki, Akira Shiose
Summary: This article reports a case of coronary artery compression associated with aortic root dilation in a patient with congenital heart disease, and introduces an effective method of treatment using valve-sparing aortic root replacement.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Justin T. Tretter, Nelson H. Burbano-Vera, Hani K. Najm
Summary: Cardiac CT and CMR are used to supplement echocardiography in evaluating aortic root and ascending aortic dilation, determining intervention timing, and guiding pre-surgical planning and post-operative surveillance. Surgical expertise alone may not be sufficient for intraoperative decision making due to the unloaded condition of the aortic root and variation in surgeons' experience. This review discusses a multimodality imaging approach, including pre-surgical CT assessment, to improve precision in aortic-valve sparing operations and personalize surgical strategies by predicting the location of ventricular components of the atrioventricular conduction axis.
ANNALS OF CARDIOTHORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Wei Wang, Xuezhou Zhang, Yong Shi, Siqi Xu, Teng Shi, Xiaotian Han, Tianxiang Gu, Enyi Shi
Summary: By reviewing the literature, it was found that valve-sparing aortic root replacement (VSRR) has more advantages in terms of patient prognosis compared to total aortic root replacement (TRR). However, the methodological quality of the relevant studies is low and lacks high-quality evidence to support this.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Dov Levine, Parth Patel, Yanling Zhao, Patra Childress, Megan Chung, Bradley G. Leshnower, Paul Kurlansky, Craig R. Smith, Edward P. Chen, Hiroo Takayama
Summary: Long-term outcomes of David V valve-sparing aortic root replacement (VSARR) in patients with bicuspid aortic valve (BAV) were compared to those with tricuspid aortic valve (TAV). The survival and reoperation rates after VSARR were similar between BAV and TAV patients, but a higher incidence of reoperation was observed in BAV patients in the late years postoperatively.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Luca Koechlin, Bejtush Rrahmani, Brigitta Gahl, Denis Berdajs, Martin T. R. Grapow, Friedrich S. Eckstein, Oliver Reuthebuch
THORACIC AND CARDIOVASCULAR SURGEON
(2020)
Article
Cardiac & Cardiovascular Systems
Luca Koechlin, Evelina Macius, Josefin Kaufmann, Brigitta Gahl, Oliver Reuthebuch, Friedrich Eckstein, Denis A. Berdajs
Editorial Material
Cardiac & Cardiovascular Systems
Denis A. Berdajs
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Editorial Material
Engineering, Biomedical
Saad Abdel-Sayed, Enrico Ferrari, Phillipe Abdel-Sayed, Markus Wilhelm, Maximilian Halbe, Ludwig Karl von Segesser, Francesco Maisano, Denis Berdajs
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
(2020)
Article
Surgery
Luca Koechlin, Josefin Kaufmann, Evelina Macius, Jens Bremerich, Gregor Sommer, Brigitta Gahl, Ulrich Schurr, Martin Grapow, Oliver Reuthebuch, Friedrich Eckstein, Denis A. Berdajs
WORLD JOURNAL OF SURGERY
(2020)
Article
Surgery
Luca Koechlin, Ulrich Schurr, Jules Miazza, Sebastian Imhof, Markus Maurer, Joachim Erb, Brigitta Gahl, David Santer, Denis Berdajs, Friedrich S. Eckstein, Oliver Reuthebuch
WORLD JOURNAL OF SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Enrico Ferrari, Changtian Wang, Denis Berdajs, Ludwig Karl von Segesser
JOURNAL OF CARDIOTHORACIC SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Denis Berdajs, Ludwig K. von Segesser, Francesco Maisano, Guiseppina Milano, Enrico Ferrari
Summary: The newly developed magnetically suspended centrifugal pump head showed satisfactory hydrodynamic performance in an acute perfusion scenario without causing increased hemolysis, as demonstrated by the experimental results.
Article
Medicine, Research & Experimental
Gregory Reid, Constantin Mork, Edin Mujagic, Denis Berdajs
Summary: The case describes a bail out approach using endovascular repair to correct the deployment of a modified frozen elephant trunk stent graft in a patient with aortic dissection.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Saad Abdel-Sayed, Enrico Ferrari, Philippe Abdel-Sayed, Markus Wilhelm, Ludwig-Karl Von Segesser, Denis Berdajs
Summary: The study found that shortening the covered section of a self-expanding bidirectional arterial cannula can enhance flow rate and reduce pressure, compared to a longer covered section. The results demonstrated that the cannula with a shorter covered section had better performance, effectively lowering the risk of lower limb ischemia.
JOURNAL OF CARDIOTHORACIC SURGERY
(2021)
Review
Cardiac & Cardiovascular Systems
Gregory Reid, Constantin Mork, Brigita Gahl, Christian Appenzeller-Herzog, Ludwig K. von Segesser, Friedrich Eckstein, Denis A. Berdajs
Summary: This study systematically evaluated outcomes for patients undergoing RVAD implantation following LVAD implantation, finding that temporary RVAD implantation is associated with worse outcomes and biventricular mechanical circulatory support leads to higher mortality and incidence of adverse events compared to isolated LVAD support.
Review
Cardiac & Cardiovascular Systems
Changtian Wang, Ludwig Karl von Segesser, Denis Berdajs, Enrico Ferrari
Summary: Endovascular treatment appears to be a promising alternative to surgery for repairing dissected proximal aortic arch in highly selected cases, but further long-term studies with specifically designed devices are required to standardize this approach.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Luca Koechlin, Julia Schuerpf, Jens Bremerich, Gregor Sommer, Brigitta Gahl, Oliver Reuthebuch, Lorenz Gurke, Edin Mujagic, Friedrich Eckstein, Denis A. Berdajs
Summary: Treatment modality did not impact survival or the incidence of a neurological event in patients with acute aortic arch dissections. Patients who did not require surgical intervention during hospitalization were at a higher risk for aorta-related intervention during follow-up, indicating a potential higher risk for these patients.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2021)
Article
Medicine, General & Internal
Thibault Schaeffer, Denis Berdajs, Oliver Reuthebuch
Summary: Cusp tear is becoming a more commonly reported failure mode of the Trifecta aortic bioprosthesis. In cases where acute aortic regurgitation occurs after Trifecta implantation without endocarditis, it is important to consider a cusp tear and promptly address it through redo surgery.
CLINICAL CASE REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Enrico Ferrari, Martin Scoglio, Giulia Piazza, Francesco Maisano, Ludwig Karl von Segesser, Denis Berdajs
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2020)