Article
Psychology, Clinical
Klara Olofsdotter Lauri, Erik Andersson, David Mataix-Cols, Lisa Norlin, Viktor Eriksson, Karin Melin, Fabian Lenhard, Eva Serlachius, Kristina Aspvall
Summary: This study presents two-year follow-up data from a non-inferiority trial comparing stepped-care and in-person CBT for pediatric obsessive-compulsive disorder. Both treatment approaches demonstrated similar long-term effects, with the majority of participants showing positive responses two years after treatment.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2023)
Article
Behavioral Sciences
Bethany M. Wootton, Sarah McDonald, Maral Melkonian, Eyal Karin, Nickolai Titov, Blake F. Dear
Summary: Self-guided internet-delivered cognitive-behavioural therapy (ICBT) may be an effective treatment for individuals with obsessive-compulsive disorder (OCD), particularly for those who cannot or do not wish to engage with a mental health professional. The study found significant improvement in symptoms from pre-treatment to post-treatment and 3-month follow-up.
COGNITIVE BEHAVIOUR THERAPY
(2023)
Article
Medicine, General & Internal
Kristina Aspvall, Filipa Sampaio, Fabian Lenhard, Karin Melin, Lisa Norlin, Eva Serlachius, David Mataix-Cols, Erik Andersson
Summary: For young people with obsessive-compulsive disorder, a low-cost digital intervention followed by in-person treatment for nonresponders was found to be cost-effective compared with in-person cognitive behavior therapy alone. This study suggests that guided internet-delivered cognitive behavioral therapy within a stepped-care model may be a more efficient treatment option for children and adolescents with OCD.
Article
Psychology, Clinical
Bethany M. Wootton, Eyal Karin, Blake F. Dear, Lauren Staples, Olav Nielssen, Rony Kayrouz, Nickolai Titov
Summary: ICBT is an effective treatment for OCD, as shown by data from Australia's MindSpot Clinic. Results indicated significant improvements in OCD symptoms at posttreatment and three-month follow up. However, future research is needed to explore the utility of ICBT in routine care settings.
JOURNAL OF ANXIETY DISORDERS
(2021)
Article
Psychology, Multidisciplinary
Sila Derin, Orcun Yorulmaz
Summary: The current study compared the effectiveness of internet-delivered cognitive bias modification interventions for obsessive-compulsive disorder (OCD) symptoms. The findings showed that both Combined Cognitive Bias Modification (iCBM-C) and Interpretation (iCBM-I) interventions were more effective than Attention (iCBM-A) intervention in reducing OCD beliefs and negative OC-relevant interpretations. Although both interventions reduced OCD symptoms, only iCBM-I was superior to the wait-list control group.
CURRENT PSYCHOLOGY
(2023)
Article
Psychology, Multidisciplinary
Faranak Kadivari, Mahmoud Najafi, Vahid Khosravani
Summary: This study found that childhood maltreatment has both direct and indirect effects on obsessive-compulsive symptoms, with the indirect effect mediated by the behavioral inhibition system. The findings highlight the role of the behavioral inhibition system in linking childhood maltreatment to obsessive-compulsive symptomology.
CURRENT PSYCHOLOGY
(2023)
Review
Psychiatry
Louise Destree, Mary-Ellen E. Brierley, Lucy Albertella, Laura Jobson, Leonardo F. Fontenelle
Summary: This study conducted a systematic review on the relationships between childhood trauma and obsessive-compulsive symptoms (OCS) severity. The results showed a significant relationship between exposure to childhood trauma and OCS severity in both clinical and non-clinical populations. It was also found that a range of childhood trauma types, rather than a single type, was associated with OCD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Psychiatry
Laura Marie Hoppen, Nora Kuck, Paul-Christian Buerkner, Eyal Karin, Bethany M. Wootton, Ulrike Buhlmann
Summary: This study found that technology-delivered CBT is effective for individuals with OCD. Compared to passive control groups, technology-delivered CBT showed significant improvements in reducing OCD symptoms.
Article
Psychology, Clinical
Katherine Parkin, Shanquan Chen, Marjan Biria, James Plaistow, Helen Beckwith, Isaac Jarratt-Barnham, Nuria Segarra, Yulia Worbe, Naomi A. Fineberg, Rudolf N. Cardinal, Trevor W. Robbins, Emilio Fernandez-Egea
Summary: Obsessive-compulsive symptoms (OCS) commonly occur in patients treated with clozapine and can significantly affect subjective wellbeing. This study found that OCS severity had a negative impact on wellbeing scores, independent of depressive and psychotic symptoms. However, OCS did not impair general functioning. Obsessional thinking and hoarding behavior, rather than compulsions, were specifically associated with decreased wellbeing, possibly due to the nature of the compulsions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Multidisciplinary
Tania Moretta, Giulia Buodo
Summary: The study found that hoarding, obsessing, and depression symptoms were positively linked to Internet use disorder severity, with hoarding having the greatest diagnostic power and accuracy. Individuals with mild to moderate Internet use disorder were characterized by a network of strong and positive associations of affective and obsessive-compulsive symptoms. These findings may encourage future longitudinal studies to identify potential clinical criteria for diagnosing Internet use disorder and treatment targets.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Difan Wang, Bingyan Lin, Fen Xiong, Yu Deng, Lin Zhang
Summary: This study investigated the effects of online self-help iACT linear intervention and iACT loop intervention on sleep quality, obsessive-compulsive symptoms, and psychological flexibility in nurses. The results showed that both interventions had a positive impact on these factors, with the iACT loop model showing greater effectiveness in enhancing psychological flexibility.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Multidisciplinary
Mustafa Kerim Simsek, Ismail Secer
Summary: This study developed a CBT-based psychoeducation practice to reduce obsessive-compulsive symptoms in Turkish adolescents. The effectiveness of the practice was tested using both quantitative and qualitative methods. It was found that the practice was effective in reducing OCD symptoms in the Turkish adolescent sample, except for the neutralizing dimension.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Clinical Neurology
Karsten Hollmann, Katharina Allgaier, Carolin S. Hohnecker, Heinrich Lautenbacher, Verena Bizu, Matthias Nickola, Gunilla Wewetzer, Christoph Wewetzer, Tord Ivarsson, Norbert Skokauskas, Lidewij H. Wolters, Gudmundur Skarphedinsson, Bernhard Weidle, Else de Haan, Nor Christan Torp, Scott N. Compton, Rosa Calvo, Sara Lera-Miguel, Anna Haigis, Tobias J. Renner, Annette Conzelmann
Summary: This study shows that internet-based CBT for pediatric OCD is feasible and well received by patients and their parents. The use of smartphone apps and video conferencing in therapy helps alleviate symptoms, and most patients find the quality of this new treatment approach to be high.
JOURNAL OF NEURAL TRANSMISSION
(2021)
Article
Clinical Neurology
Shruti S. Kinkel-Ram, William Grunewald, Shelby N. Ortiz, Joshua M. Magee, April R. Smith
Summary: This study revealed a bidirectional longitudinal relationship between eating disorders and obsessive-compulsive disorder, particularly in terms of cognitive symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Shruti S. Kinkel-Ram, William Grunewald, Shelby N. Ortiz, Joshua M. Magee, April R. Smith
Summary: The study found a bidirectional, longitudinal relationship between symptoms of eating disorders (ED) and obsessive-compulsive disorder (OCD), particularly in terms of cognitive symptoms. However, this longitudinal association was only present at certain time points.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Maria Bragesjo, Filip K. Arnberg, Klara Olofsdotter Lauri, Kristina Aspvall, Josefin Sarnholm, Erik Andersson
Summary: This study evaluated the effectiveness of a novel, scalable and digital early version of an intervention called Condensed Internet-Delivered Prolonged Exposure (CIPE) in reducing post-traumatic stress symptoms. The results showed significant reductions in symptoms of post-traumatic stress in the CIPE group, with a moderate effect size at week 3 and a large effect size at week 7. The effects were maintained at the 6-month follow-up.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Fabian Lenhard, Kristina Aspvall, Erik Andersson, Johan Ahlen, Eva Serlachius, Malin Lavner, Anna Brodin, David Mataix-Cols
Summary: This study compares the economic costs of pediatric OCD with a control group and finds that pediatric OCD is associated with higher healthcare costs, parental absence from work, and school productivity loss. The total societal burden of pediatric OCD in Sweden is estimated to be 94.3 million euros per year.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Psychology, Developmental
Charlotte L. Hall, Louise Marston, Kareem Khan, Beverley J. Brown, Charlotte Sanderson, Per Andren, Sophie Bennett, Isobel Heyman, David Mataix-Cols, Eva Serlachius, Chris Hollis, Tara Murphy
Summary: A study on children and young people with tic disorders found that the COVID-19 pandemic did not significantly impact existing tic symptoms, regardless of age, gender, symptoms of anxiety, or autism spectrum disorder.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Neurosciences
Tianyang Zhang, Gustaf Brander, Josef Isung, Kayoko Isomura, Anna Sidorchuk, Henrik Larsson, Zheng Chang, David Mataix-Cols, Lorena Fernandez de la Cruz
Summary: This study aimed to investigate the association between prenatal and early childhood infections and the risk of OCD and TS/CTD. The results showed a positive correlation between prenatal and early childhood infections and the risk of OCD and TS/CTD at the population level. However, these associations were no longer significant in sibling analyses.
BIOLOGICAL PSYCHIATRY
(2023)
Article
Psychology, Developmental
Benedetta Monzani, Deanna Fallah, Daniel Rautio, Martina Gumpert, Amita Jassi, Lorena Fernandez de la Cruz, David Mataix-Cols, Georgina Krebs
Summary: The study provides empirical support for the use of the BDD-YBOCS-A in children and adolescents with BDD, showing good internal consistency, reliability, and sensitivity to change in 251 patients.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Allergy
Marianne Bonnert, Bjorn Roelstraete, Sten-Erik Bergstrom, Johan Bjureberg, Erik Andersson, Catarina Almqvist
Summary: The study aimed to investigate the validity of two novel scales, the Fear of Asthma Symptoms scale (FAS) and the Asthma Behavior Checklist (ABC). Data was collected online from 188 adult participants with asthma and self-reported anxiety related to asthma. The results showed that both FAS and item-reduced ABC-8 demonstrated convergent and divergent validity, as well as good internal consistency and test-retest reliability. The findings suggest that these scales could be helpful in identifying excessive fear and avoidance in asthma patients and studying anxiety-related mechanisms.
Article
Psychology, Clinical
Johan Ahlen, Johan Bjureberg, Fabian Lenhard, Tove Wahlund, Johanna Linde, David Mataix-Cols
Summary: This study found that there is a group of individuals who experience impairing levels of obsessional jealousy and perceive a need for help with their difficulties. Further research is needed to explore the prevalence and clinical characteristics of these individuals. The development of jealousy-specific psychological models and treatments is recommended.
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY
(2023)
Article
Psychiatry
David Mataix-Cols, Lorena Fernandez de la Cruz, Elles De Schipper, Ralf Kuja-Halkola, Cynthia M. Bulik, James J. Crowley, Janina Neufeld, Christian Rueck, Kristiina Tammimies, Paul Lichtenstein, Sven Boelte, Jan C. Beucke
Summary: This study aims to investigate environmental risk factors for OCD by studying Swedish identical twins, collecting biological specimens, conducting clinical assessments, and performing multimodal brain imaging. So far, 43 pairs of twins have been recruited for the study, including 21 discordant for OCD.
Article
Pharmacology & Pharmacy
Kayoko Isomura, Xinchen Wang, Zheng Chang, Clara Hellner, Jan Hasselstrom, Isabella Ekheden, Nitya Jayaram-Lindstrom, Paul Lichtenstein, Brian M. D'Onofrio, David Mataix-Cols, Anna Sidorchuk
Summary: Despite being discouraged, long-term use of BZDR remains frequent. The study aimed to assess the proportion of long-term BZDR use in different age groups, identify 5-year BZDR use trajectories, and explore factors associated with long-term use and distinct trajectories. The findings highlight the importance of raising awareness and providing support to prescribers to make evidence-based decisions on BZDR treatment across the lifespan.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Psychology, Clinical
Oskar Flygare, Erik Andersson, Gjermund Glimsdal, David Mataix-Cols, Diana Pascal, Christian Rueck, Jesper Enander
Summary: This study conducted a cost-effectiveness analysis of internet-delivered cognitive behaviour therapy for body dysmorphic disorder (BDD-NET) and found that BDD-NET is more cost-effective compared to online supportive psychotherapy.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2023)
Article
Psychology, Clinical
Lina Lundstrom, Oskar Flygare, Ekaterina Ivanova, David Mataix-Cols, Jesper Enander, Diana Pascal, Long -Long Chen, Erik Andersson, Christian Ruck
Summary: This study evaluated the implementation of therapist-guided internet-delivered cognitive behaviour therapy (ICBT) for obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD) in the Swedish public health system. The results showed that ICBT was efficacious in reducing symptoms and could be reproduced in a clinical setting. The implementation of OCD-NET and BDD-NET in the Swedish public health service was deemed suitable.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2023)
Article
Psychology, Clinical
Klara Olofsdotter Lauri, Erik Andersson, David Mataix-Cols, Lisa Norlin, Viktor Eriksson, Karin Melin, Fabian Lenhard, Eva Serlachius, Kristina Aspvall
Summary: This study presents two-year follow-up data from a non-inferiority trial comparing stepped-care and in-person CBT for pediatric obsessive-compulsive disorder. Both treatment approaches demonstrated similar long-term effects, with the majority of participants showing positive responses two years after treatment.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2023)
Review
Behavioral Sciences
Erland Axelsson, Dorian Kern, Erik Hedman-Lagerlof, Perjohan Lindfors, Josefin Palmgren, Hugo Hesser, Erik Andersson, Robert Johansson, Ola Olen, Marianne Bonnert, Maria Lalouni, Brjann Ljotsson
Summary: This systematic review and meta-analysis examined the effects of various psychological treatments on irritable bowel syndrome (IBS). The results showed that exposure therapy and hypnotherapy had significant additional effects compared to attention controls. Exposure therapy was found to be a particularly promising treatment for IBS.
COGNITIVE BEHAVIOUR THERAPY
(2023)
Article
Medicine, Research & Experimental
Sofia Jagholm, Sara Lindstedt, Erik Andersson, David Mataix-Cols, Lorena Fernandez de la Cruz, Christian Ruck, Volen Z. Ivanov
Summary: This study aims to evaluate the effectiveness of in-home decluttering for individuals with hoarding disorder. Participants will receive 12-week group cognitive behavioral therapy and then be randomized into either the in-home decluttering group or the waitlist group. The primary endpoint is the outcome 10 weeks after randomization, and the cost-effectiveness of the intervention will also be assessed. Recruitment is expected to be completed by December 2024.