Glycopolymers in molecular recognition, biomimicking and glycotechnology: a review

Glycopolymers are multifunctional bio-mimetic supramolecules that can emulate the functions of glycopeptides. Entitled to molecular recognition, these molecules appertain to amplify the original bio-molecular interactions with lectins. It is ubiquitous that glycopolymers offer the potential to be explored for targeted drug delivery and tumor cell treatment, unfolding new dawn in tissue engineering. Moreover, their self-assembly trait is advantageous in medical adhesives and implants. This review abridges gap, associating physiology of bio-recognition, glyco-polymeric integration, and chemical changes that follow. Techniques for synthesis of these artificial linkers, their properties, characterization analysis, and methodologies to improve binding rates and bioactivity of glycopolymers are also enlisted.

Automated summary

Glycopolymers are multifunctional bio-mimetic molecules that mimic the functions of glycopeptides, showing potential for targeted drug delivery and tumor cell treatment. This review bridges the gap between bio-recognition physiology, glyco-polymeric integration, and chemical changes, discussing synthesis techniques, properties, and methods to improve bioactivity of glycopolymers.