Feedback Regulation of O-GlcNAc Transferase through Translation Control to Maintain Intracellular O-GlcNAc Homeostasis

Diabetes enhances translation of Cd40 mRNA in murine retinal Müller glia via a 4E-BP1/2-dependent mechanism

(2020) Sadie K. Dierscke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAc regulates gene expression by controlling detained intron splicing

(2020) Zhi-Wei Tan et al.   NUCLEIC ACIDS RESEARCH

Targeting O-GlcNAcylation to develop novel therapeutics

(2020) Yi Zhu et al.   MOLECULAR ASPECTS OF MEDICINE

O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1-dependent mitochondrial dysfunction in retina

(2019) Sadie K. Dierschke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of a compensatory regulation of colonic O-GlcNAc transferase and O-GlcNAcase expression in response to disruption of O-GlcNAc homeostasis

(2019) Amélie Decourcelle et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cross regulation between mTOR signaling and O-GlcNAcylation

(2018) Ninon Very et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer

(2018) Kevin Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma

(2018) Yi-Cheng Lin et al.   Oncotarget

Protein O-GlcNAcylation: emerging mechanisms and functions

(2017) Xiaoyong Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or γH2AX

(2017) Koji Hayakawa et al.   Epigenetics & Chromatin

A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis

(2017) Sung-Kyun Park et al.   Cell Reports

Potential coordination role between O-GlcNAcylation and epigenetics

(2017) Donglu Wu et al.   Protein & Cell

Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms

(2016) Stefan Burén et al.   CANCER CELL

A Small Molecule That Inhibits OGT Activity in Cells

(2015) Rodrigo F. Ortiz-Meoz et al.   ACS Chemical Biology

O-GlcNAc signaling in cancer metabolism and epigenetics

(2015) Jay Prakash Singh et al.   CANCER LETTERS

E2F1 Transcription Factor RegulatesO-linkedN-acetylglucosamine (O-GlcNAc) Transferase andO-GlcNAcase Expression

(2015) Senthilkumar Muthusamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer

(2015) V. L. Sodi et al.   MOLECULAR CANCER RESEARCH

Inhibition of mTOR affects protein stability of OGT

(2014) S Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

O-GlcNAc and the Epigenetic Regulation of Gene Expression

(2014) Brian A. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates histone H2B O-GlcNAcylation

(2014) Qiuran Xu et al.   NUCLEIC ACIDS RESEARCH

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling

(2014) Mame Daro Faye et al.   Jove-Journal of Visualized Experiments

Three Decades of Research on O-GlcNAcylation – A Major Nutrient Sensor That Regulates Signaling, Transcription and Cellular Metabolism

(2014) Gerald W. Hart   Frontiers in Endocrinology

O-GlcNAcase Expression is Sensitive to Changes in O-GlcNAc Homeostasis

(2014) Zhen Zhang et al.   Frontiers in Endocrinology

O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease

(2013) Michelle R. Bond et al.   Annual Review of Nutrition

O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

(2013) H. M. Itkonen et al.   CANCER RESEARCH

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

(2013) Sean J. Humphrey et al.   Cell Metabolism

Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1-Dependent Mechanism

(2013) M. D. Dennis et al.   DIABETES

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

(2013) Rachel Deplus et al.   EMBO JOURNAL

TET3-OGT interaction increases the stability and the presence of OGT in chromatin

(2013) Ryo Ito et al.   GENES TO CELLS

Rapid and sensitive liquid chromatography–tandem mass spectrometry method for determination of 1-β-d-arabinofuranosyluracil in human plasma and application to therapeutic drug monitoring in patient with leukemia

(2013) Chuanrong Liao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The mTOR Signalling Pathway in Human Cancer

(2012) Helena Pópulo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

β-N-Acetylglucosamine (O-GlcNAc) Is a Novel Regulator of Mitosis-specific Phosphorylations on Histone H3

(2012) Jerry J. Fong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

Modification of Histones by Sugar β-N-Acetylglucosamine (GlcNAc) Occurs on Multiple Residues, Including Histone H3 Serine 10, and Is Cell Cycle-regulated

(2011) Suisheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyperglycemia-InducedO-GlcNAcylation and Truncation of 4E-BP1 Protein in Liver of a Mouse Model of Type 1 Diabetes

(2011) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GlcNAcylation of histone H2B facilitates its monoubiquitination

(2011) Ryoji Fujiki et al.   NATURE

O-Linked β-N-acetylglucosamine (O-GlcNAc) Regulates Stress-induced Heat Shock Protein Expression in a GSK-3β-dependent Manner

(2010) Zahra Kazemi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation Dynamics during Early Differentiation of Human Embryonic Stem Cells

(2009) Dennis Van Hoof et al.   Cell Stem Cell