Treatment of primary and metastatic breast and pancreatic tumors upon intravenous delivery of a PRDM14 ‐specific chimeric siRNA /nanocarrier complex

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers

(2019) Sumiyo Watanabe et al.   Nature Communications

PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer

(2018) Chiharu Moriya et al.   FEBS Open Bio

Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer

(2017) Hiroaki Taniguchi et al.   Oncotarget

The role of PRDMs in cancer: one family, two sides

(2016) Slim Mzoughi et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Breast Cancer Genomics From Microarrays to Massively Parallel Sequencing: Paradigms and New Insights

(2015) Charlotte K. Y. Ng et al.   JNCI-Journal of the National Cancer Institute

Breast Cancer Genomics From Microarrays to Massively Parallel Sequencing: Paradigms and New Insights

(2015) Charlotte K. Y. Ng et al.   JNCI-Journal of the National Cancer Institute

PRDM14 Ensures Naive Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells

(2013) Masashi Yamaji et al.   Cell Stem Cell

Current challenges and opportunities in nonclinical safety testing of biologics

(2013) Sven Kronenberg et al.   DRUG DISCOVERY TODAY

High expression of PRDM14 correlates with cell differentiation and is a novel prognostic marker in resected non-small cell lung cancer

(2013) Tiehong Zhang et al.   MEDICAL ONCOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Enhanced specificity of HPV16 E6E7 siRNA by RNA–DNA chimera modification

(2011) K Yamato et al.   CANCER GENE THERAPY

Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors

(2011) E J Dettman et al.   ONCOGENE

siRNA-Based Therapy Ameliorates Glomerulonephritis

(2010) H. Shimizu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

(2010) Ziyang Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells

(2008) Norihiro Tsuneyoshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect

(2008) Kumiko Ui-Tei et al.   NUCLEIC ACIDS RESEARCH