The occurrence of lupus nephritis is regulated by USP7-mediated JMJD3 stabilization

Xenon blunts NF-κB/NLRP3 inflammasome activation and improves acute onset of accelerated and severe lupus nephritis in mice

(2020) Shin-Ruen Yang et al.   KIDNEY INTERNATIONAL

Protecting the kidney in systemic lupus erythematosus: from diagnosis to therapy

(2020) Naomi I. Maria et al.   Nature Reviews Rheumatology

P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6

(2020) Xi-Bao Zhao et al.   Aging-US

An Update on the Diagnosis and Management of Lupus Nephritis

(2020) Myrto Kostopoulou et al.   Current Rheumatology Reports

NF-kB signaling in myeloid cells mediates the pathogenesis of immune-mediated nephritis

(2019) Samantha A. Chalmers et al.   JOURNAL OF AUTOIMMUNITY

Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease

(2019) Radhika Rawat et al.   CURRENT OPINION IN CELL BIOLOGY

JMJD3 in the regulation of human diseases

(2019) Xiangxian Zhang et al.   Protein & Cell

Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies

(2017) Jian Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

USP7 is associated with greater disease activity in systemic lupus erythematosus via stabilization of the IFNα receptor

(2017) Ying Yu et al.   Molecular Medicine Reports

Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus

(2017) Heng Yin et al.   Oncotarget

H3K27 Demethylase JMJD3 Employs the NF- B and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis

(2016) W.-Y. Park et al.   CANCER RESEARCH

Update on Lupus Nephritis

(2016) Salem Almaani et al.   Clinical Journal of the American Society of Nephrology

USP7 promotes cell proliferation through the stabilization of Ki-67 protein in non-small cell lung cancer cells

(2016) Chao Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

(2016) Qian Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone H3K27 Demethylase JMJD3 in Cooperation with NF-κB Regulates Keratinocyte Wound Healing

(2016) Jungtae Na et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Current and Emerging Therapies for Lupus Nephritis

(2016) S. V. Parikh et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Expression of TLR-7, MyD88, NF-kB, and INF-α in B Lymphocytes of Mayan Women with Systemic Lupus Erythematosus in Mexico

(2016) Guillermo Valencia Pacheco et al.   Frontiers in Immunology

NF-κB in inflammation and renal diseases

(2015) Haisong Zhang et al.   Cell and Bioscience

Metabolic control of the epigenome in systemic Lupus erythematosus

(2013) Zachary Oaks et al.   AUTOIMMUNITY

Bay11-7082 attenuates murine lupus nephritis via inhibiting NLRP3 inflammasome and NF-κB activation

(2013) Jijun Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-DNA autoantibodies initiate experimental lupus nephritis by binding directly to the glomerular basement membrane in mice

(2012) Meera R. Krishnan et al.   KIDNEY INTERNATIONAL

Modulation of nuclear factor-κB activity can influence the susceptibility to systemic lupus erythematosus

(2008) Alexis M. Kalergis et al.   IMMUNOLOGY