Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development

Variability within rare cell states enables multiple paths toward drug resistance

(2021) Benjamin L. Emert et al.   NATURE BIOTECHNOLOGY

Single-cell analyses reveal the clonal and molecular aetiology of Flt3L-induced emergency dendritic cell development

(2021) Dawn S. Lin et al.   NATURE CELL BIOLOGY

Lineage tracing on transcriptional landscapes links state to fate during differentiation

(2020) Caleb Weinreb et al.   SCIENCE

Dendritic cell development at a clonal level within a revised ‘continuous’ model of haematopoiesis

(2020) Shalin H. Naik   MOLECULAR IMMUNOLOGY

An Erg-driven transcriptional program controls B cell lymphopoiesis

(2020) Ashley P. Ng et al.   Nature Communications

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

(2019) Michaël Chopin et al.   IMMUNITY

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis

(2019) Madison J. Kelly et al.   Nature Communications

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

(2019) D. Merino et al.   Nature Communications

Benchmarking single cell RNA-sequencing analysis pipelines using mixture control experiments

(2019) Luyi Tian et al.   NATURE METHODS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

(2019) Regine J. Dress et al.   NATURE IMMUNOLOGY

Engineering dendritic cell vaccines to improve cancer immunotherapy

(2019) Caleb R. Perez et al.   Nature Communications

Orchestrating single-cell analysis with Bioconductor

(2019) Robert A. Amezquita et al.   NATURE METHODS

Causes and Consequences of Hematopoietic Stem Cell Heterogeneity

(2018) Simon Haas et al.   Cell Stem Cell

Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing

(2018) Miles B. Horton et al.   JOURNAL OF IMMUNOLOGY

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

(2018) Amir Giladi et al.   NATURE CELL BIOLOGY

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

(2018) Patrick Fernandes Rodrigues et al.   NATURE IMMUNOLOGY

SAVER: gene expression recovery for single-cell RNA sequencing

(2018) Mo Huang et al.   NATURE METHODS

DiSNE Movie Visualization and Assessment of Clonal Kinetics Reveal Multiple Trajectories of Dendritic Cell Development

(2018) Dawn S. Lin et al.   Cell Reports

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

(2018) Shiro Tara et al.   BLOOD

scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data

(2018) Luyi Tian et al.   PLoS Computational Biology

Single-cell mapping of lineage and identity in direct reprogramming

(2018) Brent A. Biddy et al.   NATURE

Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies

(2017) Tomoyuki Tanaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human haematopoietic stem cell lineage commitment is a continuous process

(2017) Lars Velten et al.   NATURE CELL BIOLOGY

Single-Cell Multiomics: Multiple Measurements from Single Cells

(2017) Iain C. Macaulay et al.   TRENDS IN GENETICS

Fate Mapping and Quantitation of Hematopoiesis In Vivo

(2016) Thomas Höfer et al.   Annual Review of Immunology

Transcriptional Control of Dendritic Cell Development

(2016) Theresa L. Murphy et al.   Annual Review of Immunology

A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation

(2016) S. Nestorowa et al.   BLOOD

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

(2016) Franziska Paul et al.   CELL

Functions of Murine Dendritic Cells

(2016) Vivek Durai et al.   IMMUNITY

Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition

(2016) Hélène Salmon et al.   IMMUNITY

Single-cell analysis of mixed-lineage states leading to a binary cell fate choice

(2016) Andre Olsson et al.   NATURE

Challenges in long-term imaging and quantification of single-cell dynamics

(2016) Stavroula Skylaki et al.   NATURE BIOTECHNOLOGY

Klf4 Expression in Conventional Dendritic Cells Is Required for T Helper 2 Cell Responses

(2015) Roxane Tussiwand et al.   IMMUNITY

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow

(2015) Andreas Schlitzer et al.   NATURE IMMUNOLOGY

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

(2015) Brandon J. Aubrey et al.   Cell Reports

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Cellular barcoding: A technical appraisal

(2014) Shalin H. Naik et al.   EXPERIMENTAL HEMATOLOGY

Interferon Regulatory Factor 8 (IRF8) Interacts with the B Cell Lymphoma 6 (BCL6) Corepressor BCOR

(2014) Jeongheon Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2

(2014) Hiyaa S. Ghosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

L-Myc expression by dendritic cells is required for optimal T-cell priming

(2014) Wumesh KC et al.   NATURE

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage

(2013) Barbara U. Schraml et al.   CELL

Diverse and heritable lineage imprinting of early haematopoietic progenitors

(2013) Shalin H. Naik et al.   NATURE

Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection

(2013) Pierre Guermonprez et al.   NATURE MEDICINE

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

(2012) Tamar Hashimshony et al.   Cell Reports

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

Bcl6 Is Required for the Development of Mouse CD4+ and CD8 + Dendritic Cells

(2010) H. Ohtsuka et al.   JOURNAL OF IMMUNOLOGY

Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells

(2010) C. Eidenschenk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

A single-cell pedigree analysis of alternative stochastic lymphocyte fates

(2009) E. D. Hawkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic Cytokines Can Instruct Lineage Choice

(2009) M. A. Rieger et al.   SCIENCE

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE