Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity

(2020) Abigail Jarret et al.   CELL

Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

(2020) Jing Ni et al.   IMMUNITY

The NK cell–cancer cycle: advances and new challenges in NK cell–based immunotherapies

(2020) Tobias Bald et al.   NATURE IMMUNOLOGY

An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials

(2019) Wei Xu et al.   IMMUNITY

Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

(2019) Naomi A. Yudanin et al.   IMMUNITY

Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

(2019) Jennifer A. Walker et al.   IMMUNITY

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

(2019) Hadas Keren-Shaul et al.   Nature Protocols

Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues

(2019) Marina Cella et al.   NATURE IMMUNOLOGY

NK Cell Metabolism and Tumor Microenvironment

(2019) Iñigo Terrén et al.   Frontiers in Immunology

Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes

(2019) Tsukasa Nabekura et al.   IMMUNITY

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

(2018) Jan P. Böttcher et al.   CELL

Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response

(2018) Nicholas M. Adams et al.   IMMUNITY

Innate Lymphoid Cells: Diversity, Plasticity, and Unique Functions in Immunity

(2018) Marco Colonna   IMMUNITY

Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation

(2018) Maxime Danilo et al.   Cell Reports

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells

(2018) Henrique Borges da Silva et al.   NATURE

GOnet: a tool for interactive Gene Ontology analysis

(2018) Mikhail Pomaznoy et al.   BMC BIOINFORMATICS

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

(2018) Patrick L. Collins et al.   CELL

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice

(2018) Adeline Crinier et al.   IMMUNITY

Spatial and temporal coordination of antiviral responses by group 1 ILCs

(2018) Nicholas M. Adams et al.   IMMUNOLOGICAL REVIEWS

Molecular definition of group 1 innate lymphoid cells in the mouse uterus

(2018) Iva Filipovic et al.   Nature Communications

Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells

(2017) David H. Raulet et al.   IMMUNOLOGICAL REVIEWS

The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes

(2017) Beena Jeevan-Raj et al.   Cell Reports

Metabolic Regulation of Natural Killer Cell IFN-γ Production

(2016) Annelise Y. Mah et al.   CRITICAL REVIEWS IN IMMUNOLOGY

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

(2016) Rebecca B. Delconte et al.   IMMUNITY

Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands

(2016) Victor S. Cortez et al.   IMMUNITY

Diversity and function of group 1 innate lymphoid cells

(2016) Victor S. Cortez et al.   IMMUNOLOGY LETTERS

Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage

(2016) Olga Pikovskaya et al.   JOURNAL OF IMMUNOLOGY

Nuclear receptor 4A (NR4A) family – orphans no more

(2016) Stephen Safe et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Development of innate lymphoid cells

(2016) Erin C Zook et al.   NATURE IMMUNOLOGY

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival

(2016) Whitney Rabacal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

(2016) M. Peng et al.   SCIENCE

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Unique Eomes+ NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy

(2016) Elisa Montaldo et al.   Frontiers in Immunology

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

(2015) Roni Nowarski et al.   CELL

Innate lymphoid cells: new insights into function and development

(2015) Victor S. Cortez et al.   CURRENT OPINION IN IMMUNOLOGY

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

(2015) C. N. Johnstone et al.   Disease Models & Mechanisms

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

(2015) Mary J. van Helden et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide-induced tumor necrosis factor-α factor enhances inflammation and is associated with cancer (Review)

(2015) JUNRONG ZOU et al.   Molecular Medicine Reports

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

(2015) Michelle L Robinette et al.   NATURE IMMUNOLOGY

Innate lymphoid cells: A new paradigm in immunology

(2015) G. Eberl et al.   SCIENCE

Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells

(2015) Camille A. Spinner et al.   Scientific Reports

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

(2014) Cécile Daussy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A committed precursor to innate lymphoid cells

(2014) Michael G. Constantinides et al.   NATURE

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

Ly49 Receptors: Innate and Adaptive Immune Paradigms

(2014) Mir Munir A. Rahim et al.   Frontiers in Immunology

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells

(2013) Z. Husain et al.   JOURNAL OF IMMUNOLOGY

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

(2013) Christoph S. N. Klose et al.   NATURE

The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation

(2012) Scott M. Gordon et al.   IMMUNITY

HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

(2012) Jr-Wen Shui et al.   NATURE

Resistance to age-related, normal body weight gain in RGS2 deficient mice

(2011) Caroline Nunn et al.   CELLULAR SIGNALLING

Cutting Edge: Regulator of G Protein Signaling-1 Selectively Regulates Gut T Cell Trafficking and Colitic Potential

(2011) D. L. Gibbons et al.   JOURNAL OF IMMUNOLOGY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Cutting Edge: IL-15-Independent NK Cell Response to Mouse Cytomegalovirus Infection

(2009) J. C. Sun et al.   JOURNAL OF IMMUNOLOGY

Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen

(2009) M. M. Fluck et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Filamins Regulate Cell Spreading and Initiation of Cell Migration

(2009) Massimiliano Baldassarre et al.   PLoS One