Inflammatory cytokines in atherosclerosis: current therapeutic approaches

Comparative Safety of Interleukin-1 Blockade With Anakinra in Patients With ST-Segment Elevation Acute Myocardial Infarction (from the VCU-ART and VCU-ART2 Pilot Studies)

(2015) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Prognostic and Therapeutic Implications of Statin and Aspirin Therapy in Individuals With Nonobstructive Coronary Artery DiseaseSignificance

(2015) Benjamin J.W. Chow et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atorvastatin treatment improves endothelial function through endothelial progenitor cells mobilization in ischemic heart failure patients

(2015) Evangelos Oikonomou et al.   ATHEROSCLEROSIS

Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet

(2015) A. Abderrazak et al.   CIRCULATION

Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

(2015) Dipak P. Ramji et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Rheumatoid arthritis and coronary atherosclerosis: two cousins engaging in a dangerous liaison

(2015) Roland Klingenberg et al.   EUROPEAN HEART JOURNAL

Rheumatoid arthritis is associated with a more severe presentation of acute coronary syndrome and worse short-term outcome

(2015) Ängla Mantel et al.   EUROPEAN HEART JOURNAL

Differential effects of anti-TNF-α and anti-IL-12/23 agents on human leukocyte–endothelial cell interactions

(2015) Cesar Ríos-Navarro et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Aspirin regulates hepatocellular lipid metabolism by activating AMPK signaling pathway

(2015) Zhenxing He et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Newly Identified Antiatherosclerotic Activity of Methotrexate and Adalimumab: Complementary Effects on Lipoprotein Function and Macrophage Cholesterol Metabolism

(2015) Nicoletta Ronda et al.   Arthritis & Rheumatology

Methotrexate, Cyclosporine A, and Biologics Protect against Atherosclerosis in Rheumatoid Arthritis

(2015) Bartłomiej Kisiel et al.   Journal of Immunology Research

Low dose aspirin is associated with plasma chemerin levels and may reduce adipose tissue inflammation

(2014) Magdalena Herová et al.   ATHEROSCLEROSIS

Increased Benefit of Interleukin-1 Inhibition on Vascular Function, Myocardial Deformation, and Twisting in Patients With Coronary Artery Disease and Coexisting Rheumatoid Arthritis

(2014) Ignatios Ikonomidis et al.   Circulation-Cardiovascular Imaging

Decrease of Asymmetric Dimethyl Arginine After Anti-TNF Therapy in Patients with Rheumatoid Arthritis

(2014) Francesca Romana Spinelli et al.   DRUG DEVELOPMENT RESEARCH

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study

(2014) A. C. Morton et al.   EUROPEAN HEART JOURNAL

Anti-inflammatory therapies for cardiovascular disease

(2014) P. M. Ridker et al.   EUROPEAN HEART JOURNAL

Relationship Between Inflammation and Benefits of Early High-Dose Rosuvastatin on Contrast-Induced Nephropathy in Patients With Acute Coronary Syndrome

(2014) Anna Toso et al.   JACC-Cardiovascular Interventions

Anti-TNF-α therapy improves insulin sensitivity in non-diabetic patients with psoriasis: a 6-month prospective study

(2014) T. Pina et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Low-Dose Aspirin for Prevention of Cardiovascular Disease in Patients with Chronic Kidney Disease

(2014) Ae Jin Kim et al.   PLoS One

The effects of golimumab on subclinical atherosclerosis and arterial stiffness in ankylosing spondylitis--a randomized, placebo-controlled pilot trial

(2014) L.-S. Tam et al.   RHEUMATOLOGY

Can suppression of inflammation by anti-TNF prevent progression of subclinical atherosclerosis in inflammatory arthritis?

(2014) L.-S. Tam et al.   RHEUMATOLOGY

Beneficial effects of low-dose aspirin on aortic stiffness in hypertensive patients

(2014) Panagiota Pietri et al.   VASCULAR MEDICINE

Extracellular signal-regulated kinase-5: Novel mediator of insulin and tumor necrosis factor α-stimulated vascular cell adhesion molecule-1 expression in vascular cells 细胞外信号调节激酶-5：一种新的调节胰岛素与肿瘤坏死因子α刺激下的血管细胞上的血管细胞粘附分子-1表达的介质

(2014) Daniel Z. Mackesy et al.   Journal of Diabetes

Rationale and design of the EMBRACE STEMI Study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction

(2013) Anjan K. Chakrabarti et al.   AMERICAN HEART JOURNAL

Dose-dependent effects of short term atorvastatin treatment on arterial wall properties and on indices of left ventricular remodeling in ischemic heart failure

(2013) Dimitris Tousoulis et al.   ATHEROSCLEROSIS

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

(2013) Daniel Medeiros Moreira et al.   CARDIOLOGY

Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations

(2013) L. Tóth et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non–ST-Segment Elevation Myocardial Infarction

(2013) Jean-Claude Tardif et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Early High-Dose Rosuvastatin for Contrast-Induced Nephropathy Prevention in Acute Coronary Syndrome

(2013) Mario Leoncini et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Therapeutic Inhibition of TNF on Circulating Endothelial Progenitor Cells in Patients with Rheumatoid Arthritis

(2013) F. R. Spinelli et al.   MEDIATORS OF INFLAMMATION

Mitochondrial inner membrane lipids and proteins as targets for decreasing cardiac ischemia/reperfusion injury

(2013) David A. Brown et al.   PHARMACOLOGY & THERAPEUTICS

Aortic stiffness is increased in polymyalgia rheumatica and improves after steroid treatment

(2012) Giuseppe Schillaci et al.   ANNALS OF THE RHEUMATIC DISEASES

Effect of shear stress, statins and TNF-α on hemostatic genes in human endothelial cells

(2012) N. Bergh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

Pharmacogenetic Determinants of Statin-Induced Reductions in C-Reactive Protein

(2012) Audrey Y. Chu et al.   Circulation-Cardiovascular Genetics

Serum interleukin‐6 levels in response to methotrexate treatment in psoriatic patients

(2012) Tamilselvi Elango et al.   CLINICA CHIMICA ACTA

Cox-2 inhibitors and cardiovascular disease: considerable heat, but not much light

(2012) S. E. Nissen   EUROPEAN HEART JOURNAL

Colchicine Use Is Associated with Decreased Prevalence of Myocardial Infarction in Patients with Gout

(2012) DARIA B. CRITTENDEN et al.   JOURNAL OF RHEUMATOLOGY

Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease

(2012) Stefan M. Nidorf et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Re-evaluation of the risk for major adverse cardiovascular events in patients treated with anti-IL-12/23 biological agents for chronic plaque psoriasis: a meta-analysis of randomized controlled trials

(2012) T. Tzellos et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Interleukin-10: An Anti-Inflammatory Marker To Target Atherosclerotic Lesions via PEGylated Liposomes

(2012) Gunter Almer et al.   MOLECULAR PHARMACEUTICS

Immediate and past cumulative effects of oral glucocorticoids on the risk of acute myocardial infarction in rheumatoid arthritis: a population-based study

(2012) J. A. Avina-Zubieta et al.   RHEUMATOLOGY

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet

(2011) Janna A. van Diepen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Recent Advances on the Role of Cytokines in Atherosclerosis

(2011) Hafid Ait-Oufella et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A pilot study of endothelial dysfunction and aortic stiffness after interleukin-6 receptor inhibition in rheumatoid arthritis

(2011) A.D. Protogerou et al.   ATHEROSCLEROSIS

Local delivery of IL-2 reduces atherosclerosis via expansion of regulatory T cells

(2011) Thore Dietrich et al.   ATHEROSCLEROSIS

Anti-TNF Treatment in Rheumatoid Arthritis

(2011) Janina Geiler et al.   CURRENT PHARMACEUTICAL DESIGN

Anti-tumor necrosis factor alpha treatment with adalimumab improves significantly endothelial function and decreases inflammatory process in patients with chronic psoriasis

(2011) Georgia Avgerinou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Canakinumab (ACZ885, a fully human IgG1 anti-IL-1β mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)

(2011) Jasmin B Kuemmerle-Deschner et al.   ARTHRITIS RESEARCH & THERAPY

Effects of fluvastatin therapy on serum interleukin-18 and interleukin-10 levels in patients with acute coronary syndrome

(2010) Y. Liu et al.   ACTA CARDIOLOGICA

Tumour necrosis factor antagonist use and associated risk reduction of cardiovascular events among patients with rheumatoid arthritis

(2010) J. D. Greenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Oral Administration of an Active Form of Vitamin D 3 (Calcitriol) Decreases Atherosclerosis in Mice by Inducing Regulatory T Cells and Immature Dendritic Cells With Tolerogenic Functions

(2010) Masafumi Takeda et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Critical Function of Th17 Proinflammatory Cells in the Development of Atherosclerotic Plaque in Mice

(2010) Q. Gao et al.   JOURNAL OF IMMUNOLOGY

Systematic review and meta-analysis: Anti-tumor necrosis factor α therapy and cardiovascular events in rheumatoid arthritis

(2010) Cheryl Barnabe et al.   ARTHRITIS CARE & RESEARCH

Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study

(2009) Mike J. L. Peters et al.   ARTHRITIS AND RHEUMATISM

Improvement of lipid profile is accompanied by atheroprotective alterations in high-density lipoprotein composition upon tumor necrosis factor blockade: A prospective cohort study in ankylosing spondylitis

(2009) I. C. van Eijk et al.   ARTHRITIS AND RHEUMATISM

Aspirin Inhibits Fractalkine Expression in Atherosclerotic Plaques and Reduces Atherosclerosis in ApoE Gene Knockout Mice

(2009) Hong Liu et al.   CARDIOVASCULAR DRUGS AND THERAPY

Oral Anti-CD3 Antibody Treatment Induces Regulatory T Cells and Inhibits the Development of Atherosclerosis in Mice

(2009) Naoto Sasaki et al.   CIRCULATION

Combined effects of atorvastatin and metformin on glucose-induced variations of inflammatory process in patients with diabetes mellitus

(2009) Dimitris Tousoulis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of IL-17A Attenuates Atherosclerotic Lesion Development in ApoE-Deficient Mice

(2009) C. Erbel et al.   JOURNAL OF IMMUNOLOGY

Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT)

(2009) PAUL M. RIDKER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

(2009) Paul M Ridker et al.   LANCET

Effects of the anti-interleukin-6 receptor antibody, tocilizumab, on serum lipid levels in patients with rheumatoid arthritis

(2009) Shin-ya Kawashiri et al.   RHEUMATOLOGY INTERNATIONAL

Expression and Suppressive Effects of Interleukin-19 on Vascular Smooth Muscle Cell Pathophysiology and Development of Intimal Hyperplasia

(2008) Ying Tian et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of Interleukin-1 by Anakinra Improves Vascular and Left Ventricular Function in Patients With Rheumatoid Arthritis

(2008) Ignatios Ikonomidis et al.   CIRCULATION

Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation

(2008) Elli Stefanadi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE