Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer’s disease

Protective Effects of Anti-depressant Citalopram Against Abnormal APP Processing and Amyloid Beta-induced Mitochondrial Dynamics, Biogenesis, Mitophagy and Synaptic Toxicities in Alzheimer’s Disease

(2021) Arubala P Reddy et al.   HUMAN MOLECULAR GENETICS

Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice

(2021) Jasvinder Singh Bhatti et al.   MITOCHONDRION

Anti-brain Aging Effects of Small Molecule Inhibitor DDQ

(2021) Murali Vijayan et al.   MOLECULAR NEUROBIOLOGY

Serotonin in Health and Disease

(2020) Philippe De Deurwaerdère et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

Early Life Stress and the Onset of Obesity: Proof of MicroRNAs’ Involvement Through Modulation of Serotonin and Dopamine Systems’ Homeostasis

(2020) Gabriel Araujo Tavares et al.   Frontiers in Physiology

Association of depressive symptoms with health care utilization in older adults: Longitudinal evidence from the Survey of Health, Aging and Retirement in Europe

(2020) Kaisla Komulainen et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Mitochondria-Targeted Small Peptide, SS31 Ameliorates Diabetes Induced Mitochondrial Dynamics in Male TallyHO/JngJ Mice

(2020) Jasvinder Singh Bhatti et al.   MOLECULAR NEUROBIOLOGY

Effect of Escitalopram on Aβ levels and plaque load in an Alzheimer mouse model

(2020) John R. Cirrito et al.   NEUROLOGY

Defective mitophagy in Alzheimer’s disease

(2020) Jangampalli Adi Pradeepkiran et al.   AGEING RESEARCH REVIEWS

Synaptic basis of Alzheimer’s disease: Focus on synaptic amyloid beta, P-tau and mitochondria

(2020) Albin John et al.   AGEING RESEARCH REVIEWS

Mitophagy and the Brain

(2020) Natalie S. Swerdlow et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amyloid Beta and MicroRNAs in Alzheimer’s Disease

(2019) Nnana Amakiri et al.   Frontiers in Neuroscience

Can Healthy Diets, Regular Exercise, and Better Lifestyle Delay the Progression of Dementia in Elderly Individuals?

(2019) Elizabeth Kurudamannil George et al.   JOURNAL OF ALZHEIMERS DISEASE

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Adenovirus 36 improves glycemic control and markers of Alzheimer's disease pathogenesis

(2019) V. Hegde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diabetic Neuropathy

(2019) Elina Zakin et al.   SEMINARS IN NEUROLOGY

Alzheimer’s disease

(2018) Gøril Rolfseng Grøntvedt et al.   CURRENT BIOLOGY

Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer’s disease

(2018) P Hemachandra Reddy et al.   HUMAN MOLECULAR GENETICS

Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer’s disease

(2018) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology

(2018) Qin Zhang et al.   NEUROPHARMACOLOGY

Diversity of neurodegenerative pathophysiology in nondemented patients with major depressive disorder: Evidence of cerebral amyloidosis and hippocampal atrophy

(2018) Kuan-Yi Wu et al.   Brain and Behavior

Targeted Neurotransmitters Profiling Identifies Metabolic Signatures in Rat Brain by LC-MS/MS: Application in Insomnia, Depression and Alzheimer’s Disease

(2018) Huarong Xu et al.   MOLECULES

Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer’s disease

(2017) Ramesh Kandimalla et al.   HUMAN MOLECULAR GENETICS

Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model

(2017) Wenzhang Wang et al.   HUMAN MOLECULAR GENETICS

Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer’s Disease

(2017) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice

(2017) C.U. Von Linstow et al.   NEUROCHEMISTRY INTERNATIONAL

Beta-amyloid deposition in patients with major depressive disorder with differing levels of treatment resistance: a pilot study

(2017) Peng Li et al.   EJNMMI Research

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease

(2016) P Hemachandra Reddy et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Age, APOE and sex: Triad of risk of Alzheimer’s disease

(2016) Brandalyn C. Riedel et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Impact of physical and mental health on life satisfaction in old age: a population based observational study

(2016) Thomas Puvill et al.   BMC Geriatrics

Diabetes-associated depression: The serotonergic system as a novel multifunctional target

(2015) Deepali Gupta et al.   INDIAN JOURNAL OF PHARMACOLOGY

Ovarian steroids regulate gene expression related to DNA repair and neurodegenerative diseases in serotonin neurons of macaques

(2015) C L Bethea et al.   MOLECULAR PSYCHIATRY

An Antidepressant Decreases CSF A  Production in Healthy Individuals and in Transgenic AD Mice

(2014) Y. I. Sheline et al.   Science Translational Medicine

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

(2013) D. F. Silva et al.   HUMAN MOLECULAR GENETICS

Ascending monoaminergic systems alterations in Alzheimer's disease. Translating basic science into clinical care

(2013) Ludwig Trillo et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

Depression subtypes and 5-year risk of dementia and Alzheimer disease in patients aged 70 years

(2012) Joan Vilalta-Franch et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Effect of ovarian steroids on gene expression related to synapse assembly in serotonin neurons of macaques

(2012) Cynthia L. Bethea et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Plasma Beta Amyloid Level and Depression in Older Adults

(2012) A. L. Metti et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A mitochondrial etiology of Alzheimer and Parkinson disease

(2011) Pinar Coskun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

(2011) Marcus J. Calkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

(2011) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

(2011) M. J. Calkins et al.   HUMAN MOLECULAR GENETICS

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

(2011) U. Shirendeb et al.   HUMAN MOLECULAR GENETICS

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

(2011) U. P. Shirendeb et al.   HUMAN MOLECULAR GENETICS

Depression and risk of developing dementia

(2011) Amy L. Byers et al.   Nature Reviews Neurology

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Depression and Plasma Amyloid β Peptides in the Elderly With and Without the Apolipoprotein E4 Allele

(2009) Xiaoyan Sun et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

(2009) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Effect of ovarian hormones on genes promoting dendritic spines in laser-captured serotonin neurons from macaques

(2009) C L Bethea et al.   MOLECULAR PSYCHIATRY

Increased Neurofibrillary Tangles in Patients With Alzheimer Disease With Comorbid Depression

(2008) Michael A. Rapp et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Amyloid-  overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

(2008) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA