CaV channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeutics
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CaV channels and cancer: canonical functions indicate benefits of repurposed drugs as cancer therapeutics
Authors
Keywords
Cancer, Calcium channels, Repurposed drugs
Journal
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Volume 45, Issue 7, Pages 621-633
Publisher
Springer Nature
Online
2016-06-26
DOI
10.1007/s00249-016-1144-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Functional upregulation of the H2S/Cav3.2 channel pathway accelerates secretory function in neuroendocrine-differentiated human prostate cancer cells
- (2015) Kazuki Fukami et al. BIOCHEMICAL PHARMACOLOGY
- Ion channel expression as promising cancer biomarker
- (2015) Elena Lastraioli et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Antihypertensive medication use and incident breast cancer in women
- (2015) Elizabeth E. Devore et al. BREAST CANCER RESEARCH AND TREATMENT
- The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels
- (2015) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Identification of genomic biomarkers associated with the clinicopathological parameters and prognosis of esophageal squamous cell carcinoma
- (2015) Zhi-Zhou Shi et al. Cancer Biomarkers
- Use of Antihypertensive Medications Not Associated with Risk of Contralateral Breast Cancer among Women Diagnosed with Estrogen Receptor-Positive Invasive Breast Cancer
- (2015) L. Chen et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype
- (2015) G. Zhu et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Posttranscriptional regulation of T-type Ca 2+ channel expression by interleukin-6 in prostate cancer cells
- (2015) Erika M. Weaver et al. CYTOKINE
- Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells
- (2015) Erika M. Weaver et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Melatonin affects voltage-dependent calcium and potassium currents in MCF-7 cell line cultured either in growth or differentiation medium
- (2015) Roberta Squecco et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Ca2+ channel subunit α 1D promotes proliferation and migration of endometrial cancer cells mediated by 17β-estradiol via the G protein-coupled estrogen receptor
- (2015) Juan Hao et al. FASEB JOURNAL
- T-type calcium channel antagonists, mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines
- (2015) Weifeng Huang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- 5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth
- (2015) Ricardo Marques et al. MEDICAL ONCOLOGY
- Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition
- (2015) S. J. Davis et al. MOLECULAR CANCER THERAPEUTICS
- Epigenomic profiling of prostate cancer identifies differentially methylated genes in TMPRSS2:ERG fusion-positive versus fusion-negative tumors
- (2015) Milan S. Geybels et al. Clinical Epigenetics
- Signature Channels of Excitability no More: L-Type Channels in Immune Cells
- (2015) Bennett Davenport et al. Frontiers in Immunology
- Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer
- (2015) Xian-Jun Yu et al. EBioMedicine
- Emerging Alternative Functions for the Auxiliary Subunits of the Voltage- Gated Calcium Channels
- (2015) Franz Hofmann et al. Current Molecular Pharmacology
- Meta-Analysis of Public Microarray Datasets Reveals Voltage-Gated Calcium Gene Signatures in Clinical Cancer Patients
- (2015) Chih-Yang Wang et al. PLoS One
- Inhibition of cellular proliferation and induction of apoptosis in human lung adenocarcinoma A549 cells by T-type calcium channel antagonist
- (2014) Doo Li Choi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: Essential role of Cav3.2 channels
- (2014) Elia Ranzato et al. CELL CALCIUM
- Using predrugs to optimize drug candidates
- (2014) Rafik Karaman Expert Opinion on Drug Discovery
- Regulation of Gene Transcription by Voltage-gated L-type Calcium Channel, Cav1.3
- (2014) Ling Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β
- (2014) Marc D. Basson et al. Molecular Oncology
- T-Type Ca2+ Channel Blocker, KYS05090 Induces Autophagy and Apoptosis in A549 Cells through Inhibiting Glucose Uptake
- (2014) Hong-Kun Rim et al. MOLECULES
- Association between calcium channel blockers and breast cancer: a meta-analysis of observational studies
- (2014) Qi Chen et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?
- (2014) N. Prevarskaya et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Calcium Channel Blockers and Risk of Breast Cancer: A Meta-Analysis of 17 Observational Studies
- (2014) Wen Li et al. PLoS One
- Breast Cancer Risk and Use of Calcium Channel Blockers Using Swedish Population Registries
- (2014) Gudrun Jonasdottir Bergman et al. JAMA Internal Medicine
- Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells
- (2013) Nicholas C.K. Valerie et al. BIOCHEMICAL PHARMACOLOGY
- The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer
- (2013) Martin W. Berchtold et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- In vitro cytotoxicity on human ovarian cancer cells by T-type calcium channel blockers
- (2013) Sun Jeong Jang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid
- (2013) Devon Andres et al. BMC NEUROSCIENCE
- Identification ofTDRD1as a direct target gene ofERGin primary prostate cancer
- (2013) Joost L. Boormans et al. INTERNATIONAL JOURNAL OF CANCER
- Expression and Pharmacology of Endogenous Cav Channels in SH-SY5Y Human Neuroblastoma Cells
- (2013) Silmara R. Sousa et al. PLoS One
- The association between calcium channel blocker use and prostate cancer outcome
- (2013) Michael A. Poch et al. PROSTATE
- Cav1.3 channel α1D protein is overexpressed and modulates androgen receptor transactivation in prostate cancers11This work was partially supported by grants from DoD PCRP program (W81XWH-09-1-0455) and KUMC Valk Foundation to Dr Benyi Li, and grants from China Natural Science Foundation to Dr Benyi Li (NSFC #81172427) and Dr Jun Yang (NSFC #81101927). This project was also supported by the “Chutian Scholar” program funded by Hubei Province of China dedicated to China Three Gorges University.
- (2013) Ruibao Chen et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Use of Antihypertensive Medications and Breast Cancer Risk Among Women Aged 55 to 74 Years
- (2013) Christopher I. Li et al. JAMA Internal Medicine
- Functional coupling between large-conductance potassium channels and Cav3.2 voltage-dependent calcium channels participates in prostate cancer cell growth
- (2013) Florian Gackière et al. Biology Open
- Use of antihypertensive medications and breast cancer risk
- (2012) Babette S. Saltzman et al. CANCER CAUSES & CONTROL
- Promoter Methylation status of HIN-1 associated with outcomes of ovarian clear cell adenocarcinoma
- (2012) Chih-Ming Ho et al. Molecular Cancer
- STIM proteins: dynamic calcium signal transducers
- (2012) Jonathan Soboloff et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
- (2012) S. R. Denmeade et al. Science Translational Medicine
- Methylation profile of triple-negative breast carcinomas
- (2012) M T Branham et al. Oncogenesis
- The association between antihypertensive drug use and incidence of prostate cancer in Finland: a population-based case–control study
- (2011) Kimmo J. Kemppainen et al. CANCER CAUSES & CONTROL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Functional Characterization of Alternative Splicing in the C Terminus of L-type CaV1.3 Channels
- (2011) Bao Zhen Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical Dutch-English Lambert-Eaton Myasthenic Syndrome (LEMS) Tumor Association Prediction Score Accurately Predicts Small-Cell Lung Cancer in the LEMS
- (2011) Maarten J. Titulaer et al. JOURNAL OF CLINICAL ONCOLOGY
- Lambert–Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies
- (2011) Maarten J Titulaer et al. LANCET NEUROLOGY
- Voltage-Gated Calcium Channels
- (2011) W. A. Catterall Cold Spring Harbor Perspectives in Biology
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- High expression of large-conductance Ca2+-activated K+ channel in the CD133+ subpopulation of SH-SY5Y neuroblastoma cells
- (2010) Ji Hyun Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting CREB for Cancer Therapy: Friend or Foe
- (2010) X. Xiao et al. CURRENT CANCER DRUG TARGETS
- Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer
- (2010) Mónica Castro et al. Journal of Translational Medicine
- Channelopathies in Cav1.1, Cav1.3, and Cav1.4 voltage-gated L-type Ca2+ channels
- (2010) Jörg Striessnig et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Ion channels and the hallmarks of cancer
- (2010) Natalia Prevarskaya et al. TRENDS IN MOLECULAR MEDICINE
- Gene regulation by voltage-dependent calcium channels
- (2009) Maud Barbado et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Integration ofERGgene mapping and gene-expression profiling identifies distinct categories of human prostate cancer
- (2008) Sameer Jhavar et al. BJU INTERNATIONAL
- Use of blood-pressure-lowering medication and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort
- (2008) Carmen Rodriguez et al. CANCER CAUSES & CONTROL
- Cardiovascular Medication Use and Risk for Colorectal Cancer
- (2008) D. M. Boudreau et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Selective blockade of T-type Ca2+ channels suppresses human breast cancer cell proliferation
- (2008) James T. Taylor et al. CANCER LETTERS
- CaV3.2 T-type Calcium Channels Are Involved in Calcium-dependent Secretion of Neuroendocrine Prostate Cancer Cells
- (2008) Florian Gackière et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of Voltage- and Ca2+-dependent Gating of CaV1.3 L-type Calcium Channels by Alternative Splicing of a C-terminal Regulatory Domain
- (2008) Anamika Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Estrogen-Dependent Signaling in a Molecularly Distinct Subclass of Aggressive Prostate Cancer
- (2008) Sunita R. Setlur et al. JNCI-Journal of the National Cancer Institute
- Calcium signaling in immune cells
- (2008) Monika Vig et al. NATURE IMMUNOLOGY
- Calcium signaling and T-type calcium channels in cancer cell cycling
- (2008) James T Taylor et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
- (2008) Scott A. Tomlins et al. NEOPLASIA
- T-type Ca2+ channel expression in human esophageal carcinomas: A functional role in proliferation
- (2007) Fengmin Lu et al. CELL CALCIUM
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now