TAK-101 Nanoparticles Induce Gluten-Specific Tolerance in Celiac Disease: A Randomized, Double-Blind, Placebo-Controlled Study

Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease

(2020) Tobias L. Freitag et al.   GASTROENTEROLOGY

Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial

(2020) Maureen M. Leonard et al.   GASTROENTEROLOGY

Antigen-specific therapeutic approaches for autoimmunity

(2019) Pau Serra et al.   NATURE BIOTECHNOLOGY

Nanoparticles Containing an Insulin–ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells

(2019) Braxton L. Jamison et al.   JOURNAL OF IMMUNOLOGY

Randomised clinical trial: a placebo-controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease

(2019) Kenneth E. Truitt et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Measuring Change In Small Intestinal Histology In Patients With Celiac Disease

(2018) Daniel C Adelman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis

(2018) Prashant Singh et al.   Clinical Gastroenterology and Hepatology

Tolerogenic Ag-PLG nanoparticles induce tregs to suppress activated diabetogenic CD4 and CD8 T cells

(2018) Suchitra Prasad et al.   JOURNAL OF AUTOIMMUNITY

Coeliac disease

(2018) Benjamin Lebwohl et al.   LANCET

T Cells in Celiac Disease

(2017) Bana Jabri et al.   JOURNAL OF IMMUNOLOGY

Peptide-Conjugated Nanoparticles Reduce Positive Co-stimulatory Expression and T Cell Activity to Induce Tolerance

(2017) Robert Kuo et al.   MOLECULAR THERAPY

An antigen-encapsulating nanoparticle platform for TH1/17 immune tolerance therapy

(2017) Derrick P. McCarthy et al.   Nanomedicine-Nanotechnology Biology and Medicine

A Novel Patient-Derived Conceptual Model of the Impact of Celiac Disease in Adults: Implications for Patient-Reported Outcome and Health-Related Quality-of-Life Instrument Development

(2017) Daniel A. Leffler et al.   VALUE IN HEALTH

Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization

(2016) Charles B. Smarr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celiac disease

(2015) Peter H.R. Green et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Harnessing nanoparticles for immune modulation

(2015) Daniel R. Getts et al.   TRENDS IN IMMUNOLOGY

A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease

(2014) Zoe Hunter et al.   ACS Nano

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease

(2013) Alberto Rubio-Tapia et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

World Medical Association Declaration of Helsinki

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Validation of Morphometric Analyses of Small-Intestinal Biopsy Readouts in Celiac Disease

(2013) Juha Taavela et al.   PLoS One

Dietary gluten triggers concomitant activation of CD4+ and CD8+    T cells and    T cells in celiac disease

(2013) A. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celiac disease, eosinophilic esophagitis and gastroesophageal reflux disease, an adult population-based study

(2013) Jonas F. Ludvigsson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Antigen-Specific Tolerance by Autologous Myelin Peptide-Coupled Cells: A Phase 1 Trial in Multiple Sclerosis

(2013) A. Lutterotti et al.   Science Translational Medicine

Mild Enteropathy Celiac Disease: A Wolf in Sheep's Clothing?

(2012) Daniel Leffler et al.   Clinical Gastroenterology and Hepatology

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

(2012) Daniel R Getts et al.   NATURE BIOTECHNOLOGY

Celiac Disease

(2012) Alessio Fasano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Up-regulation of small intestinal interleukin-17 immunity in untreated coeliac disease but not in potential coeliac disease or in type 1 diabetes

(2011) A. I. Lahdenperä et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tolerance Induced by Apoptotic Antigen-Coupled Leukocytes Is Induced by PD-L1+ and IL-10-Producing Splenic Macrophages and Maintained by T Regulatory Cells

(2011) D. R. Getts et al.   JOURNAL OF IMMUNOLOGY

IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease–associated inflammation and lymphomagenesis

(2010) Georgia Malamut et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of IL-17A–Producing Cells in Celiac Disease Mucosa

(2010) Ivan Monteleone et al.   JOURNAL OF IMMUNOLOGY

Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease

(2010) J. A. Tye-Din et al.   Science Translational Medicine

Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry

(2009) Dmitry R. Bandura et al.   ANALYTICAL CHEMISTRY

Celiac Disease: From Pathogenesis to Novel Therapies

(2009) Detlef Schuppan et al.   GASTROENTEROLOGY

Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice

(2009) T. L. Freitag et al.   GUT

Gliadin Activates HLA Class I-Restricted CD8+ T Cells in Celiac Disease Intestinal Mucosa and Induces the Enterocyte Apoptosis

(2008) Giuseppe Mazzarella et al.   GASTROENTEROLOGY