Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer
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Title
Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer
Authors
Keywords
Colon Cancer, Ku70, MicroRNA, Rad51, DSB
Journal
GASTROENTEROLOGY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-03-20
DOI
10.1053/j.gastro.2021.03.027
References
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- (2019) Veronika Butin-Israeli et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2018) Sofia Mensurado et al. PLOS BIOLOGY
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- (2018) David P. Sullivan et al. Mucosal Immunology
- MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors
- (2018) Marialaura Petroni et al. Cell Death & Disease
- Intraperitoneal delivery of NanoOlaparib for disseminated late-stage cancer treatment
- (2018) Paige Baldwin et al. International Journal of Nanomedicine
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- (2017) Mark Robson et al. NEW ENGLAND JOURNAL OF MEDICINE
- High levels of tumor-associated neutrophils are associated with improved overall survival in patients with stage II colorectal cancer
- (2017) Ryan S. Berry et al. PLoS One
- NICE guidance on olaparib for maintenance treatment of patients with relapsed, platinum-sensitive, BRCA mutation-positive ovarian cancer
- (2016) Helen Tucker et al. LANCET ONCOLOGY
- DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression
- (2016) Stephanie Hampp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway
- (2014) Dipon Das et al. DNA REPAIR
- Role of Lamin B1 in Chromatin Instability
- (2014) Veronika Butin-Israeli et al. MOLECULAR AND CELLULAR BIOLOGY
- Collateral Genome Instability by DNA Damage in Mitosis
- (2014) N. Jelluma et al. Cancer Discovery
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
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- (2013) Michal Zimmermann et al. TRENDS IN CELL BIOLOGY
- Increased Intratumoral Neutrophil in Colorectal Carcinomas Correlates Closely with Malignant Phenotype and Predicts Patients' Adverse Prognosis
- (2012) Hui-Lan Rao et al. PLoS One
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
- (2011) W Chua et al. BRITISH JOURNAL OF CANCER
- Ulcerative colitis-associated colorectal cancer shows a poorer survival than sporadic colorectal cancer: A nationwide Japanese study
- (2010) Toshiaki Watanabe et al. INFLAMMATORY BOWEL DISEASES
- Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
- (2010) Mary Ellen Moynahan et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of oxaliplatin in the treatment of colorectal cancer
- (2010) Pasquale Comella Therapeutics and Clinical Risk Management
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- (2009) A. C. Chin et al. JOURNAL OF IMMUNOLOGY
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
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