Mitochondria antioxidant protection against cardiovascular dysfunction programmed by early‐onset gestational hypoxia

Assessment of tissue perfusion and vascular function in mice by scanning laser Doppler perfusion imaging

(2020) Francesca Leo et al.   BIOCHEMICAL PHARMACOLOGY

Cardiorespiratory consequences of intrauterine growth restriction: Influence of timing, severity and duration of hypoxaemia

(2020) Jack R.T. Darby et al.   THERIOGENOLOGY

Global Reach 2018: Heightened α-Adrenergic Signaling Impairs Endothelial Function During Chronic Exposure to Hypobaric Hypoxia

(2020) Michael M Tymko et al.   CIRCULATION RESEARCH

Effects of Maternal Obesity On Placental Phenotype

(2020) Abigail Fowden et al.   Current Vascular Pharmacology

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypertension Programmed in Adult Hens by Isolated Effects of Developmental Hypoxia In Ovo

(2020) Katie L. Skeffington et al.   HYPERTENSION

Placenta-targeted treatment strategies: An opportunity to impact fetal development and improve offspring health later in life

(2020) Esha Ganguly et al.   PHARMACOLOGICAL RESEARCH

Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction

(2020) K. J. Botting et al.   Science Advances

Intervention against hypertension in the next generation programmed by developmental hypoxia

(2019) Kirsty L. Brain et al.   PLOS BIOLOGY

Sex-Specific Effects of Nanoparticle-Encapsulated MitoQ (nMitoQ) Delivery to the Placenta in a Rat Model of Fetal Hypoxia

(2019) Esha Ganguly et al.   Frontiers in Physiology

Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep

(2019) Alejandro Gonzalez-Candia et al.   Redox Biology

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

(2019) Brígida R. Pinho et al.   FREE RADICAL BIOLOGY AND MEDICINE

Projected Costs of Informal Caregiving for Cardiovascular Disease: 2015 to 2035: A Policy Statement From the American Heart Association

(2018) Sandra B. Dunbar et al.   CIRCULATION

Maternal treatment with a placental-targeted antioxidant (MitoQ) impacts offspring cardiovascular function in a rat model of prenatal hypoxia

(2018) Mais M. Aljunaidy et al.   PHARMACOLOGICAL RESEARCH

Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring

(2018) Jessica H. Beeson et al.   Molecular Metabolism

Placental adaptation to early-onset hypoxic pregnancy and mitochondria-targeted antioxidant therapy in rat

(2018) Anna Maria Nuzzo et al.   AMERICAN JOURNAL OF PATHOLOGY

Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy

(2018) Youguo Niu et al.   HYPERTENSION

Regulatory crosstalk between the oxidative stress-related transcription factor Nfe2l2/Nrf2 and mitochondria

(2018) In-geun Ryoo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Postnatal effects of intrauterine treatment of the growth-restricted ovine fetus with intra-amniotic insulin-like growth factor-1

(2017) A. M. Spiroski et al.   JOURNAL OF PHYSIOLOGY-LONDON

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development

(2017) Tom J. Phillips et al.   Scientific Reports

Preterm Birth and Hypertension: Is There a Link?

(2016) Mariane Bertagnolli et al.   CURRENT HYPERTENSION REPORTS

Fetalin vivocontinuous cardiovascular function during chronic hypoxia

(2016) B. J. Allison et al.   JOURNAL OF PHYSIOLOGY-LONDON

N-Acetylcysteine, a glutathione precursor, reverts vascular dysfunction and endothelial epigenetic programming in intrauterine growth restricted guinea pigs

(2016) Emilio A. Herrera et al.   JOURNAL OF PHYSIOLOGY-LONDON

Twin Conception in Sheep Leads to Impaired Insulin Sensitivity and Sexually Dimorphic Adipose Tissue and Skeletal Muscle Phenotypes in Adulthood

(2016) Elise L. Donovan et al.   Reproductive Sciences

Effect of resveratrol on metabolic and cardiovascular function in male and female adult offspring exposed to prenatal hypoxia and a high-fat diet

(2015) Amin Shah et al.   JOURNAL OF PHYSIOLOGY-LONDON

Melatonin modulates the fetal cardiovascular defense response to acute hypoxia

(2015) Avnesh S. Thakor et al.   JOURNAL OF PINEAL RESEARCH

Prenatal Hypoxia Leads to Increased Muscle Sympathetic Nerve Activity, Sympathetic Hyperinnervation, Premature Blunting of Neuropeptide Y Signaling, and Hypertension in Adult Life

(2014) William Rook et al.   HYPERTENSION

Prenatal hypoxia programs changes in β-adrenergic signaling and postnatal cardiac contractile dysfunction

(2013) I. Lindgren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Vitamin C Prevents Intrauterine Programming of in vivo Cardiovascular Dysfunction in the Rat

(2013) Andrew D. Kane et al.   CIRCULATION JOURNAL

Antioxidant treatment improves neonatal survival and prevents impaired cardiac function at adulthood following neonatal glucocorticoid therapy

(2013) Youguo Niu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Xanthine oxidase and the fetal cardiovascular defence to hypoxia in late gestation ovine pregnancy

(2013) Andrew D. Kane et al.   JOURNAL OF PHYSIOLOGY-LONDON

Graduated effects of high-altitude hypoxia and highland ancestry on birth size

(2013) Rudy Soria et al.   PEDIATRIC RESEARCH

Developmental programming of cardiovascular disease by prenatal hypoxia

(2013) D. A. Giussani et al.   Journal of Developmental Origins of Health and Disease

Poor maternal nutrition followed by accelerated postnatal growth leads to alterations in DNA damage and repair, oxidative and nitrosative stress, and oxidative defense capacity in rat heart

(2012) Jane L. Tarry-Adkins et al.   FASEB JOURNAL

The hyperaemic response to passive leg movement is dependent on nitric oxide: a new tool to evaluate endothelial nitric oxide function

(2012) Stefan P. Mortensen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ascorbate prevents placental oxidative stress and enhances birth weight in hypoxic pregnancy in rats

(2012) H. G. Richter et al.   JOURNAL OF PHYSIOLOGY-LONDON

Developmental Programming of Cardiovascular Dysfunction by Prenatal Hypoxia and Oxidative Stress

(2012) Dino A. Giussani et al.   PLoS One

Hypoxia-derived oxidative stress mediates epigenetic repression of PKCɛ gene in foetal rat hearts

(2011) Andrew J. Patterson et al.   CARDIOVASCULAR RESEARCH

Forecasting the Future of Cardiovascular Disease in the United States

(2011) Paul A. Heidenreich et al.   CIRCULATION

Mitochondria-Targeted Antioxidants in the Treatment of Disease

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Redox modulation of the fetal cardiovascular defence to hypoxaemia

(2010) A. S. Thakor et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1receptors

(2010) Andrew M. Coney et al.   JOURNAL OF PHYSIOLOGY-LONDON

Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms

(2010) Avnesh S. Thakor et al.   JOURNAL OF PINEAL RESEARCH

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Prenatal hypoxia induces increased cardiac contractility on a background of decreased capillary density

(2009) David Hauton et al.   BMC Cardiovascular Disorders

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

(2009) Sergio Rodriguez-Cuenca et al.   FREE RADICAL BIOLOGY AND MEDICINE

β-Adrenergic receptor signaling in the heart: Role of CaMKII

(2009) Michael Grimm et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood

(2008) Christian F. Rueda-Clausen et al.   CARDIOVASCULAR RESEARCH

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE