Inhibition of pyruvate oxidation as a versatile stimulator of the hair cycle in models of alopecia

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

(2020) Bing Zhang et al.   NATURE

Deficiency of Crif1 in hair follicle stem cells retards hair growth cycle in adult mice

(2020) Jung-Min Shin et al.   PLoS One

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

(2020) Christine S. Kim et al.   Cell Metabolism

Stem cell competition orchestrates skin homeostasis and ageing

(2019) Nan Liu et al.   NATURE

Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle

(2018) Matilde Miranda et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lactate dehydrogenase activity drives hair follicle stem cell activation

(2017) Aimee Flores et al.   NATURE CELL BIOLOGY

Development of a Model for Chemotherapy-Induced Alopecia: Profiling of Histological Changes in Human Hair Follicles after Chemotherapy

(2016) Ji-Seon Yoon et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

(2016) H. Matsumura et al.   SCIENCE

Application of mitochondrial pyruvate carrier blocker UK5099 creates metabolic reprogram and greater stem-like properties in LnCap prostate cancer cells in vitro

(2015) Yali Zhong et al.   Oncotarget

Mitochondrial Metabolism of Pyruvate Is Essential for Regulating Glucose-stimulated Insulin Secretion

(2014) Jessica N. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4

(2014) Chih-Chiang Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Thinning Top: Why Old People Have Less Hair

(2014) Sashank K. Reddy et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Chronic variable stress activates hematopoietic stem cells

(2014) Timo Heidt et al.   NATURE MEDICINE

Distinct Functions for Wnt/β-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis

(2013) Yeon Sook Choi et al.   Cell Stem Cell

Pathobiology of chemotherapy-induced hair loss

(2013) Ralf Paus et al.   LANCET ONCOLOGY

Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients

(2012) N. Kluger et al.   ANNALS OF ONCOLOGY

Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

(2012) Naoki Oshimori et al.   Cell Stem Cell

New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence

(2012) Maksim V. Plikus   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells

(2011) Luis A. Garza et al.   JOURNAL OF CLINICAL INVESTIGATION

Key Roles for Transforming Growth Factor β in Melanocyte Stem Cell Maintenance

(2010) Emi K. Nishimura et al.   Cell Stem Cell

High-dose, post-transplantation cyclophosphamide to promote graft-host tolerance after allogeneic hematopoietic stem cell transplantation

(2010) Leo Luznik et al.   IMMUNOLOGIC RESEARCH

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

(2009) Valentina Greco et al.   Cell Stem Cell

Epidermal stem cell diversity and quiescence

(2009) Fiona M. Watt et al.   EMBO Molecular Medicine

Chemotherapy-Induced Alopecia

(2009) Ralph M. Trüeb   SEMINARS IN CUTANEOUS MEDICINE AND SURGERY

Epidermal stem cells are retained in vivo throughout skin aging

(2008) Adam Giangreco et al.   AGING CELL

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

(2008) Maksim V. Plikus et al.   NATURE