The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders

16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia

(2020) Greg C. Bristow et al.   Cell Reports

Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

(2020) You-Hyang Song et al.   Science Advances

Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations

(2019) Chizuru Iwasawa et al.   Molecular Brain

Circuit Mechanisms of Parkinson’s Disease

(2019) Matthew M. McGregor et al.   NEURON

Somatostatin-Expressing Interneurons Enable and Maintain Learning-Dependent Sequential Activation of Pyramidal Neurons

(2019) Avital Adler et al.   NEURON

Diversity and Function of Somatostatin-Expressing Interneurons in the Cerebral Cortex

(2019) Therese Riedemann   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent expansions of novel strategies towards the drug targeting into the brain

(2019) Amit Alexander et al.   International Journal of Nanomedicine

Two types of somatostatin-expressing GABAergic interneurons in the superficial layers of the mouse cingulate cortex

(2018) Therese Riedemann et al.   PLoS One

Striatal GABA ergic interneuron dysfunction in the Q175 mouse model of Huntington's disease

(2018) Sandra M. Holley et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Role of Somatostatin-Positive Cortical Interneurons in the Generation of Sleep Slow Waves

(2017) Chadd M. Funk et al.   JOURNAL OF NEUROSCIENCE

Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior

(2017) Tsukasa Kamigaki et al.   NATURE NEUROSCIENCE

Pasireotide for the treatment of acromegaly

(2016) Luiz Eduardo Wildemberg et al.   EXPERT OPINION ON PHARMACOTHERAPY

Brain-Wide Maps of Synaptic Input to Cortical Interneurons

(2016) N. R. Wall et al.   JOURNAL OF NEUROSCIENCE

Distinct Roles of Parvalbumin- and Somatostatin-Expressing Interneurons in Working Memory

(2016) Dohoung Kim et al.   NEURON

Somatostatin and Somatostatin-Containing Neurons in Shaping Neuronal Activity and Plasticity

(2016) Monika Liguz-Lecznar et al.   Frontiers in Neural Circuits

Trans-Blood Brain Barrier Delivery of Dopamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Rats

(2015) Richa Pahuja et al.   ACS Nano

Thalamocortical Innervation Pattern in Mouse Auditory and Visual Cortex: Laminar and Cell-Type Specificity

(2015) Xu-ying Ji et al.   CEREBRAL CORTEX

New therapeutic agents for acromegaly

(2015) Shlomo Melmed   Nature Reviews Endocrinology

Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression

(2015) Marianne L. Seney et al.   NEUROBIOLOGY OF DISEASE

Flexible Sensory Representations in Auditory Cortex Driven by Behavioral Relevance

(2015) Hiroyuki K. Kato et al.   NEURON

Huntington disease

(2015) Gillian P. Bates et al.   Nature Reviews Disease Primers

Differential Receptive Field Properties of Parvalbumin and Somatostatin Inhibitory Neurons in Mouse Auditory Cortex

(2014) L.-y. Li et al.   CEREBRAL CORTEX

Somatostatin receptor expression in hepatocellular carcinoma: prognostic and therapeutic considerations

(2014) Omar Abdel-Rahman et al.   ENDOCRINE-RELATED CANCER

Long-range and local circuits for top-down modulation of visual cortex processing

(2014) S. Zhang et al.   SCIENCE

Somatostatin analogs: does pharmacology impact antitumor efficacy?

(2014) Mounira Chalabi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis

(2013) Stefan Leucht et al.   LANCET

Distinct behavioural and network correlates of two interneuron types in prefrontal cortex

(2013) D. Kvitsiani et al.   NATURE

Neocortical Somatostatin-Expressing GABAergic Interneurons Disinhibit the Thalamorecipient Layer 4

(2013) Han Xu et al.   NEURON

Altered Cortical Expression of GABA-Related Genes in Schizophrenia: Illness Progression vs Developmental Disturbance

(2013) G. D. Hoftman et al.   SCHIZOPHRENIA BULLETIN

The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species

(2013) Marianne L. Seney et al.   Frontiers in Psychiatry

Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures

(2012) Hongkui Zeng et al.   CELL

The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

(2012) Koichi Wakabayashi et al.   MOLECULAR NEUROBIOLOGY

A neural circuit for spatial summation in visual cortex

(2012) Hillel Adesnik et al.   NATURE

Viral disruption of the blood–brain barrier

(2012) Katherine R. Spindler et al.   TRENDS IN MICROBIOLOGY

Nanotechnological advances for the delivery of CNS therapeutics

(2011) Ho Lun Wong et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanisms of Inhibition within the Telencephalon: “Where the Wild Things Are”

(2011) Gord Fishell et al.   Annual Review of Neuroscience

Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression

(2011) J-P Guilloux et al.   MOLECULAR PSYCHIATRY

Neural mechanisms of the cognitive model of depression

(2011) Seth G. Disner et al.   NATURE REVIEWS NEUROSCIENCE

Reduced somatostatin in subgenual anterior cingulate cortex in major depression

(2011) Adam Tripp et al.   NEUROBIOLOGY OF DISEASE

Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategies

(2011) James W. Murrough et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

How Inhibition Shapes Cortical Activity

(2011) Jeffry S. Isaacson et al.   NEURON

Somatostatin Receptor 1 and 5 Double Knockout Mice Mimic Neurochemical Changes of Huntington's Disease Transgenic Mice

(2011) Padmesh S. Rajput et al.   PLoS One

Hippocampal interneurons are abnormal in schizophrenia

(2011) Christine Konradi et al.   SCHIZOPHRENIA RESEARCH

Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia

(2011) Daniel J. Lodge et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Octreotide Long-Acting Release (LAR)

(2010) Lily P.H. Yang et al.   DRUGS

Pharmacokinetic evaluation of lanreotide

(2010) Miao Hu et al.   Expert Opinion on Drug Metabolism & Toxicology

Somatostatin Contributes to In Vivo Gamma Oscillation Modulation and Odor Discrimination in the Olfactory Bulb

(2010) G. Lepousez et al.   JOURNAL OF NEUROSCIENCE

Genetic Fate Mapping Reveals That the Caudal Ganglionic Eminence Produces a Large and Diverse Population of Superficial Cortical Interneurons

(2010) G. Miyoshi et al.   JOURNAL OF NEUROSCIENCE

Phospholipids and Lipid-Based Formulations in Oral Drug Delivery

(2010) Gert Fricker et al.   PHARMACEUTICAL RESEARCH

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Potential of solid lipid nanoparticles in brain targeting

(2008) Indu Pal Kaur et al.   JOURNAL OF CONTROLLED RELEASE

Cortistatin—Functions in the central nervous system

(2008) Luis de Lecea   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Instantaneous correlation of excitation and inhibition during ongoing and sensory-evoked activities

(2008) Michael Okun et al.   NATURE NEUROSCIENCE

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

(2008)   NATURE REVIEWS NEUROSCIENCE