SARS-CoV-2 entry inhibitors by dual targeting TMPRSS2 and ACE2: An in silico drug repurposing study

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

(2020) Francesca Coperchini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Clinical Presentation of COVID-19: A Systematic Review Focusing on Upper Airway Symptoms

(2020) Andrea Lovato et al.   ENT-EAR NOSE & THROAT JOURNAL

Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing Study

(2020) Junmei Wang   Journal of Chemical Information and Modeling

Potential therapeutic agents against COVID-19

(2020) Chih-Chia Lu et al.   Journal of the Chinese Medical Association

Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial

(2020) Ivan Fan-Ngai Hung et al.   LANCET

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses

(2020) Shibo Jiang et al.   TRENDS IN IMMUNOLOGY

In vitro activity of lopinavir/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses

(2020) Chang Kyung Kang et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro

(2020) Ka-Tim Choy et al.   ANTIVIRAL RESEARCH

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis

(2020) Yuan Hou et al.   BMC Medicine

Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents

(2020) Markus Zeitlinger et al.   CLINICAL PHARMACOKINETICS

Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis

(2020) Derek K Chu et al.   LANCET

Targeting SARS-CoV-2 Main Protease: A Computational Drug Repurposing Study

(2020) Krishnaprasad Baby et al.   ARCHIVES OF MEDICAL RESEARCH

ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19

(2020) Donato Zipeto et al.   Frontiers in Immunology

OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules

(2019) Katarina Roos et al.   Journal of Chemical Theory and Computation

Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry

(2019) Kelly L. Damm-Ganamet et al.   Journal of Chemical Information and Modeling

Alvimopan combined with enhanced recovery strategy for managing postoperative ileus after open abdominal surgery: a systematic review and meta-analysis

(2016) Liang-Liang Xu et al.   JOURNAL OF SURGICAL RESEARCH

Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review

(2015) Werner Mendling et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Review and Meta-Analysis of Incidence and Clinical Predictors of Anthracycline Cardiotoxicity

(2013) Marzia Lotrionte et al.   AMERICAN JOURNAL OF CARDIOLOGY

ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis

(2013) AC Simões e Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Homology modeling a fast tool for drug discovery: Current perspectives

(2012) VK Vyas et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Graphical analysis of pH-dependent properties of proteins predicted using PROPKA

(2011) Michał Rostkowski et al.   BMC STRUCTURAL BIOLOGY

Drug-like Bioactive Structures and Conformational Coverage with the LigPrep/ConfGen Suite: Comparison to Programs MOE and Catalyst

(2010) I-Jen Chen et al.   Journal of Chemical Information and Modeling