Article
Cardiac & Cardiovascular Systems
Beatrice Santens, Alexander Van De Bruaene, Pieter De Meester, Guido Claessen, Philip Moons, Piet Claus, Kaatje Goetschalckx, Jan Bogaert, Werner Budts
Summary: This study assessed exercise capacity and ventricular function in patients after arterial switch operation (ASO) for complete transposition of the great arteries. It found that some asymptomatic ASO patients have electrical, left ventricle, and right ventricle changes at rest, and signs of fibrosis. Exercise capacity is impaired and seems to be related to ventricular function.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Clement Batteux, Samya Abakka, Regis Gaudin, Pascal Vouhe, Olivier Raisky, Damien Bonnet
Summary: 3D modeling can predict late coronary events after ASO, with the geometric parameters of the left coronary artery being associated with coronary events and having predictive value.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Craig S. Broberg, Alexandra van Dissel, Jessica Minnier, Jamil Aboulhosn, Robert M. Kauling, Salil Ginde, Eric Krieger, Fred Rodriguez, Tripti Gupta, Sangeeta Shah, Anitha S. John, Timothy Cotts, W. Aaron Kay, Marissa Kuo, Cindy Dwight, Patricia Woods, Jeremy Nicolarsen, Berardo Sarubbi, Flavia Fusco, Petra Antonova, Susan Fernandes, Jasmine Grewal, Jonathan Cramer, Paul Khairy, Pastora Gallego, Clare O'Donnell, Jane Hannah, Mikael Dellborg, Carla P. Rodriguez-Monserrate, Isabelle Vonder Muhll, Stephen Pylypchuk, Anthony Magalski, Frank Han, Adam M. Lubert, Joseph Kay, Elizabeth Yeung, Jolien Roos-Hesselink, David Baker, David S. Celermajer, Luke J. Burchill, William M. Wilson, Joshua Wong, Shelby Kutty, Alexander R. Opotowsky
Summary: For patients with d-TGA and a systemic right ventricle after atrial switch surgery, the progression to end-stage heart failure or death is slow. The study identified predictive factors associated with adverse outcomes and developed a simplified scoring system to identify high-risk patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Soichiro Kitamura, Hisateru Tachimori, Arata Murakami, Hiroaki Kawata, Hajime Ichikawa, Hiroaki Miyata
Summary: This study evaluated the 90-day mortality and the effect of rescue or urgent coronary revascularization in children undergoing arterial switch operation for transposition of the great arteries. The 90-day mortality was found to better represent perioperative outcomes compared to the 30-day mortality. Patients on ECMO had a higher 90-day mortality, and coronary revascularization showed a salvaging effect.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Inga Voges, Christien Boll, Amke Caliebe, Dominik Gabbert, Anselm Uebing, Sylvia Krupickova
Summary: Patients with TGA after ASO often have different PA anatomy and common PA stenoses. This study used MRI to establish disease-specific reference ranges for PA dimensions and biventricular volumes and mass in 69 pediatric patients with TGA. The results showed strong associations between body surface area and PA diameters, as well as between height and biventricular volumes.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Supreet P. Marathe, Mariana Chavez, Antonia Schulz, Lynn A. Sleeper, Gerald R. Marx, Sitaram M. Emani, Pedro J. Del Nido, Christopher W. Baird
Summary: This study investigated the contemporary outcomes of the double switch operation for patients with congenitally corrected transposition of the great arteries. The results showed promising outcomes of the surgery, but highlighted the anticipated problems of progressive neoaortic regurgitation and the need for reoperations.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Tyson A. Fricke, Edward Buratto, Robert G. Weintraub, Andrew Bullock, Gavin Wheaton, Leeanne Grigg, Patrick Disney, Yves D'Udekem, Christian P. Brizard, Igor E. Konstantinov
Summary: This study aimed to evaluate the long-term outcomes of patients undergoing ASO at a single institution. The results showed high survival rates and normal LV systolic function in patients after 25 years of ASO surgery. However, some patients may face issues such as neoaortic valve regurgitation and the need for reoperation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Karel Koubsky, Roman Gebauer, Tomas Tlaskal, Tomas Matejka, Rudolf Poruban, Denisa Jicinska, Bohumil Hucin, Jan Janousek, Vaclav Chaloupecky
Summary: The long-term survival of children undergoing ASO is excellent with low rates of coronary artery reinterventions. Patients with intramural coronary artery are at higher risk of coronary artery reintervention and mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Julio Sotelo, Israel Valverde, Duarte Martins, Damien Bonnet, Nathalie Boddaert, Kuberan Pushparajan, Sergio Uribe, Francesca Raimondi
Summary: This study conducted a comprehensive haemodynamic analysis using 4D-flow MRI data to investigate the relationship between aorta dilation in TGA patients post-ASO and controls. Significant differences in haemodynamic parameters were found between the two groups, with potential biomarkers identified for early prediction of aortic root dilatation in TGA patients.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Margaret Irwin, Geoffrey Binney, Kimberlee Gauvreau, Sitaram Emani, Elizabeth D. Blume, David W. Brown
Summary: Patients with bicuspid native pulmonary valve (BNPV) undergoing arterial switch operation have similar short-term outcomes compared to those with tricuspid native pulmonary valve, but are more prone to and experience earlier aortic regurgitation and neo-aortic root dilation.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Yusuke Yamamoto, Koji Nomura, Takahiro Tomoyasu, Fumiaki Murayama, Sho Isobe
Summary: This study retrospectively examined the impact of an improved coronary transfer technique in arterial switch operation for transposition of the great arteries. The oblique coronary transfer technique showed good patency of the coronary arteries and contributed to improved postoperative mortality rates, with no deaths and no need for mechanical circulatory support during a median follow-up of 5.3 years. The freedom from re-intervention rate was 85.6% over 8 years, with most transplanted coronary arteries remaining patent.
JOURNAL OF CARDIAC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Odilia Woudstra, Doris Skoric-Milosavljevic, Barbara J. M. Mulder, Folkert J. Meijboom, Marco C. Post, Monique R. M. Jongbloed, Arie P. J. van Dijk, Joost P. van Melle, Thelma C. Konings, Alex Postma, Connie R. Bezzina, Berto J. Bouma, Michael W. T. Tanck
Summary: Research suggests that common genetic variants may contribute to the heterogeneity in clinical course and improve risk stratification in patients with transposition of the great arteries after atrial switch operation. These findings support the hypothesis that incorporating genetic variants into risk assessment may be beneficial.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Makoto Nakamura, Kazuyoshi Kanno, Masahiko Nishioka
Summary: In patients with transposition of the great arteries, aortopulmonary collateral arteries are common after catheterization. This case report describes symptomatic aortopulmonary collateral arteries following arterial switch, which required support with a centrifugal pump and left ventricular assistive device, along with emergent coil embolization. After embolization, hemodynamics significantly improved, and the postoperative recovery was uneventful.
ANNALS OF THORACIC SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
Leo J. Engele, Barbara J. M. Mulder, Jan W. Schoones, Philippine Kies, Anastasia D. Egorova, Hubert W. Vliegen, Mark G. Hazekamp, Berto J. Bouma, Monique R. M. Jongbloed
Summary: The study found that coronary complications can occur in adults after ASO, even though data is limited. High-risk features can be identified through routine coronary CT scans. Based on the research findings, a baseline assessment of the coronary arteries in all ASO adults is recommended.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Leonardo Augusto Miana, Valdano Manuel, Valeria Melo Moreira, Marcelo Biscegli Jatene
Summary: This case study presented a patient with complex pulmonary artery stenosis treated with bilateral pulmonary artery stenting, aortic valve replacement, pulmonary valve repair, and interposition of a Y-shaped graft. The patient had a successful recovery and was discharged home asymptomatic after antibiotic treatment for endocarditis.
HEART LUNG AND CIRCULATION
(2021)
Article
Cardiac & Cardiovascular Systems
Claire J. Koppel, Hubert W. Vliegen, Regina Bokenkamp, A. Derk Jan Ten Harkel, Philippine Kies, Anastasia D. Egorova, J. Wouter Jukema, Mark G. Hazekamp, Martin J. Schalij, Adriana C. Gittenberger-de Groot, Monique R. M. Jongbloed
Summary: The Leiden Convention coronary coding system structures the diverse anatomical patterns of coronary arteries, applicable to different cardiac imaging techniques, facilitating uniform annotation for thoracic surgeons, cardiologists, and radiologists.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Review
Pediatrics
Jef Van den Eynde, Simone Bartelse, Friso M. Rijnberg, Shelby Kutty, Monique R. M. Jongbloed, Christiaan de Bruin, Mark G. Hazekamp, Saskia Le Cessie, Arno A. W. Roest
Summary: This study mapped the somatic growth patterns of single ventricle patients after Fontan palliation and summarized key modifiers that may improve growth. The findings provide guidance for optimizing somatic growth strategies and can serve as a benchmark for clinical follow-up.
Article
Cardiac & Cardiovascular Systems
Odilia Woudstra, Doris Skoric-Milosavljevic, Barbara J. M. Mulder, Folkert J. Meijboom, Marco C. Post, Monique R. M. Jongbloed, Arie P. J. van Dijk, Joost P. van Melle, Thelma C. Konings, Alex Postma, Connie R. Bezzina, Berto J. Bouma, Michael W. T. Tanck
Summary: Research suggests that common genetic variants may contribute to the heterogeneity in clinical course and improve risk stratification in patients with transposition of the great arteries after atrial switch operation. These findings support the hypothesis that incorporating genetic variants into risk assessment may be beneficial.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jef van den Eynde, Roel L. F. van der Palen, Ingmar Knobbe, Bart Straver, Lauran Stoger, Gabriella Ricciardi, Thelma C. Konings, Monique R. M. Jongbloed, Mark G. Hazekamp
Summary: This study retrospectively analyzed 14 rare cases of using the modified Yacoub aortocoronary flap technique in coronary transfer surgery, and found that it can serve as an effective bail-out option with excellent results among hospital survivors.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Justin Wallet, Yoshitaka Kimura, Nico A. Blom, Sumche Man, Monique R. M. Jongbloed, Katja Zeppenfeld
Summary: This study found that the presence of R'' wave in lead V1 and/or a negative terminal QRS portion (NTP) duration >= 80 ms in lead aVF on sinus rhythm electrocardiogram (ECG) can serve as indicators for detecting slow conducting anatomical isthmus (SCAI 3) in repaired tetralogy of Fallot (rTOF) patients and predicting their risk of ventricular tachycardia (VT).
Article
Cardiac & Cardiovascular Systems
Marieke Nederend, Philippine Kies, Madelien Regeer, Hubert W. Vliegen, Bart J. A. Mertens, Danielle Robbers-Visser, Berto J. Bouma, Laurens F. Tops, Martin J. Schalij, Monique R. M. Jongbloed, Anastasia D. Egorova
Summary: This study investigates the tolerability and effects of sacubitril/valsartan in adult patients with sRV failure. The results show that treatment with sacubitril/valsartan is associated with a low rate of adverse effects and leads to persistent improvement in 6-minute walking distance, NT-proBNP levels, and echocardiographic parameters of sRV function.
Review
Cardiac & Cardiovascular Systems
Leo J. Engele, Roel L. F. van der Palen, Anastasia D. Egorova, Margot M. Bartelings, Lambertus J. Wisse, Claire A. Glashan, Philippine Kies, Hubert W. Vliegen, Mark G. Hazekamp, Barbara J. M. Mulder, Marco C. De Ruiter, Berto J. Bouma, Monique R. M. Jongbloed
Summary: This study investigated the changes in fibrosis and innervation state in the hearts of patients with transposition of the great arteries (TGA) and correlated the findings with clinical literature. The results showed that diffuse interstitial fibrosis was already present in newborn TGA hearts, and the amount of fibrosis was significantly higher in hearts after surgical correction. Additionally, there was a decrease in nerve innervation after the arterial switch operation (ASO).
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Ralph M. L. Neijenhuis, Madelien V. Regeer, Frank van der Kley, Hubert W. Vliegen, Monique R. M. Jongbloed, Philippine Kies, Martin J. Schalij, J. Wouter Jukema, Anastasia D. Egorova
Summary: Baffle leaks, a common complication after the atrial switch procedure, can have significant implications on the hemodynamic course and prognosis of patients. Our report highlights three cases of baffle leaks in patients with systemic right ventricular failure, with successful percutaneous closure in two cases and conservative management in one case. These cases underscore the importance of a patient-tailored approach when addressing baffle leaks.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Marieke Nederend, J. Lauran Stoger, Anastasia D. Egorova, Daniela Q. C. M. Barge-Schaapveld, Monique R. M. Jongbloed
Summary: This article presents a follow-up report of an adult patient after Fontan palliation, who experienced multiple late complications, including refractory protein losing enteropathy. Genetic evaluation identified a variant of uncertain significance in the BRAF gene associated with Noonan spectrum disorders, which are notorious for lymphedema and protein losing enteropathy.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2023)
Article
Medicine, General & Internal
Abdelhak El Bouziani, Lars S. Witte, Berto J. Bouma, Monique R. M. Jongbloed, Danielle Robbers-Visser, Bart Straver, Marcel A. M. Beijk, Philippine Kies, David R. Koolbergen, Frank van der Kley, Martin J. Schalij, Robbert J. de Winter, Anastasia D. Egorova
Summary: Transcatheter valve interventions have become a valid alternative to conventional surgical treatment in selected acquired heart disease patients. However, there is a lack of literature on percutaneous atrioventricular (AV) valve interventions in adult congenital heart disease (ACHD) patients, including technical aspects, hemodynamic effects, and clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Ralph M. L. Neijenhuis, Marieke Nederend, Monique R. M. Jongbloed, Philippine Kies, Joris I. Rotmans, Hubert W. Vliegen, J. Wouter Jukema, Anastasia D. Egorova
Summary: This study described the initial experience with dapagliflozin in patients with systemic right ventricular (sRV) failure, focusing on its tolerability and short-term effects on clinical outcomes. The results showed that dapagliflozin exhibited good tolerability and had a positive impact on cardiac function and renal function. However, large-scale prospective studies are needed to thoroughly evaluate the effects of SGLT2i in the growing sRV failure population.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Medicine, General & Internal
H. Sophia Chen, Lieke van Roon, Jan Schoones, Katja Zeppenfeld, Marco C. Deruiter, Monique R. M. Jongbloed
Summary: Cardiac sympathetic hyperinnervation occurs mainly in the borderzone three days after myocardial infarction and remains present for at least 3 months. It is most commonly studied in male rats with permanent left anterior descending (LAD) ligation. The amount of hyperinnervation differs greatly between studies, possibly due to the differential quantification methods.
ANNALS OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Tjerry Hut, Arno Roest, Duco Gaillard, Mark Hazekamp, Pieter van den Boogaard, Hildo Lamb, Lucia Kroft, Monique Jongbloed, Jos Westenberg, Jolanda Wentzel, Friso Rijnberg, Sasa Kenjeres
Summary: Virtual expansion of Fontan conduits from 16 mm to 24-32 mm based on patient-specific flow significantly improves TCPC efficiency, while thrombosis risk remains low.
INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Marieke Nederend, Katja Zeppenfeld, Monique R. M. Jongbloed, Anastasia D. Egorova
Summary: Invasive hemodynamic contractility evaluation can help assess the potential benefit of CRT in patients with systemic right ventricular failure in the context of transposition of TGA after atrial switch. Successful CRT can result in improved sRV function, reduced TR and improved exercise capacity.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)