Article
Environmental Sciences
Jongeun Rhee, Kathryn H. Barry, Wen-Yi Huang, Joshua N. Sampson, Jonathan N. Hofmann, Debra T. Silverman, Antonia M. Calafat, Julianne Cook Botelho, Kayoko Kato, Mark P. Purdue, Sonja I. Berndt
Summary: This study investigated the association between pre-diagnostic serum PFAS concentrations and aggressive prostate cancer risk. The results showed an inverse association between PFOA and aggressive prostate cancer, but this association was no longer significant for cases diagnosed more than 3 years after blood collection.
ENVIRONMENTAL RESEARCH
(2023)
Article
Oncology
Jessica M. Madrigal, Rebecca Troisi, Helja-Marja Surcel, Hanna Ohman, Juha Kivela, Hannu Kiviranta, Panu Rantakokko, Jani Koponen, Danielle N. Medgyesi, Cari M. Kitahara, Katherine A. McGlynn, Joshua Sampson, Paul S. Albert, Mary H. Ward, Rena R. Jones
Summary: This study investigated the relationship between PFAS and thyroid cancer risk in Finnish maternity cohort. The results showed no clear association between most PFAS and thyroid cancer risk, except for PFHxS which was inversely associated. There were suggestive increased risks for PFOA, PFOS, and EtFOSAA among those diagnosed at ages <40 years.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Review
Environmental Sciences
Kyle Steenland, Andrea Winquist
Summary: This study critically reviewed the evidence relating to PFAS and cancer, finding a strong association with testicular and kidney cancer. However, there are inconsistencies in the data regarding prostate cancer. Long-term follow-up of large cohorts with high exposure contrasts is likely to provide more informative results.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Yonatal Mesfin Tefera, Sharyn Gaskin, Krystle Mitchell, David Springer, Simon Mills
Summary: This longitudinal study finds a declining trend in serum PFAS concentrations among firefighters after cessation of exposure to PFAS-containing foams. The main contaminants identified are PFOS, PFHxS, and PFOA. Firefighters under the age of 55, those who used PFAS in the past ten years, or those who had little to no frequency of PFAS exposure in their previous employment experienced a higher annual percentage reduction in serum PFAS concentrations.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
R. K. Rowe, F. B. Barakat, D. Patch, K. Weber
Summary: This study investigates the diffusion and sorption of PFOA, PFOS, PFBS, 6:2 FTS, and GenX through TPU and PVC-EIA liners. The results show significant diffusion through TPU, especially at higher temperatures, while PVC-EIA liners exhibit excellent diffusive resistance, especially at 23°C. Sorption tests show no measurable partitioning of compounds to the liners examined.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Odei Garcia-Garin, Asuncion Borrell, Pere Colomer-Vidal, Morgana Vighi, Nuria Trilla-Prieto, Alex Aguilar, Manel Gazo, Begona Jimenez
Summary: This study investigates the biomagnification of Poly- and Perfluoroalkyl Substances (PFAS) in striped dolphins in the North-Western Mediterranean Sea and examines the temporal trends of PFAS concentrations over the past three decades. The results show that PFAS, especially the long-chain compounds, have bioaccumulated in dolphins and may have potential health effects. The findings contribute to the understanding of PFAS pollution in marine ecosystems and can support future ecological risk assessments and management strategies.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Shuting Tian, Tianyuan Xu, Leqi Fang, Yangmo Zhu, Fan Li, Rodney Nelson Leary, Man Zhang, Dongye Zhao, Te-Yang Soong, Hang Shi
Summary: The study tested a two-step 'Concentrate-&-Destroy' technology for removing and degrading PFAS in landfill leachate using a specific adsorptive photocatalyst. The technology effectively removed various PFAS and achieved regeneration and degradation under UV.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Jiao-Jiao Liu, Xin-Xin Cui, Ya-Wen Tan, Peng-Xin Dong, Yan-Qiu Ou, Qing-Qing Li, Chu Chu, Lu-Yin Wu, Li-Xia Liang, Shuang-Jian Qin, Mohammed Zeeshan, Yang Zhou, Li-Wen Hu, Ru-Qing Liu, Xiao-Wen Zeng, Guang-Hui Dong, Xiao-Miao Zhao
Summary: Experimental evidence suggests a potential hepatotoxic effect of per- and polyfluoroalkyl substances (PFAS) and their alternatives, impacting liver function biomarkers. Individuals with higher serum PFAS levels were associated with greater odds of abnormal liver function.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Biology
Francesca Marchetto, Marco Roverso, Davide Righetti, Sara Bogialli, Francesco Filippini, Elisabetta Bergantino, Eleonora Sforza
Summary: This study assessed the possibility of using Synechocystis sp. PCC6803 in PFAS-enriched waters, finding that short-term exposure to PFOA and PFOS did not affect growth, and long-term exposure showed no toxicity and partial removal of the compounds. Measurements also suggested a role for Synechocystis in the sequestration of PFAS, providing insights for potential metabolic engineering applications in phyco-remediation.
Article
Engineering, Environmental
Narasimhan Loganathan, Angela K. Wilson
Summary: The presence of PFAS in natural settings poses a threat to the environment and human health. Soils and sediments are important pathways for PFAS exposure. This study provides molecular-level insights into the adsorption and dynamics of PFAS molecules in clay minerals. The findings contribute to the development of degradation and mitigation strategies.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Edwin Barth, John McKernan, Diana Bless, Kavitha Dasu
Summary: A two-phased bench-scale study evaluated the potential use of various sorbents for chemical stabilizing agents in the solidification/stabilization treatment process of PFAS contaminated soils. Results indicated that GAC showed the highest sorption performance for PFAS compounds, significantly reducing leachability, suggesting its effectiveness in immobilization of PFAS contaminants in soil.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2021)
Article
Environmental Sciences
Ana Lopez-Antia, Marwa M. Kavelaars, Wendt Mueller, Lieven Bervoets, Marcel Eens
Summary: Perfluoroalkyl acids (PFAAs) are currently a focus of scientific and regulatory attention. This study examined PFAAs exposure in chicks of a generalist seabird species, finding that maternal transfer plays a significant role in determining chicks' PFAAs burden. The association between specific stable isotopes and PFOS suggests a higher exposure in birds with a predominantly marine diet.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Gwynn R. Johnson, Mark L. Brusseau, Kenneth C. Carroll, Geoffrey R. Tick, Candice M. Duncan
Summary: A meta-analysis of PFAS concentrations in groundwater across 20 countries showed distinct differences in concentration ranges between sites, with soil generally having higher PFAS levels. Reported presence of PFAS in all media in various regions highlights the potential impact on water resources and ecosystems. The study underscores the importance of considering background PFAS concentrations in risk assessments due to their ubiquitous distribution and potential health implications.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Paul E. Rosenfeld, Kenneth R. Spaeth, Linda L. Remy, Vera Byers, Stuart A. Muerth, Ryan C. Hallman, Jasmine Summers-Evans, Sofia Barker
Summary: Firefighters are at risk of exposure to PFASs, especially from AFFF. They have elevated serum levels of long-chain PFASs. Due to the persistence and bioaccumulation of PFAS chemicals, firefighters experience cumulative effects from AFFF exposure throughout their careers. Studies have shown an elevated risk of various cancers among firefighters due to PFAS exposure, necessitating further research.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Ian L. Pepper, Mark L. Brusseau, Frank J. Prevatt, Barbara A. Escobar
Summary: The research investigated the impact of long-term land application of biosolids on PFAS presence in soils and found that biosolids and irrigation water are important sources of PFAS in soils for all study sites. Not all PFAS detected in biosolids were present in the soil, and the concentrations of long-chain PFAS decreased significantly with depth.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Meeting Abstract
Toxicology
A. M. Vinggaard, M. Lamoree, B. I. Escher, J. -P. Antignac, M. Scholze, T. K. Jensen, M. Herzler, M. Audebert, T. Hamers, A. Kortenkamp, F. Busquet, M. Piumatti, G. Dervilly, M. J. Valente, R. Cariou, S. Moteau, M. Oelgeschlager, K. Renko, S. Schmeisser, D. Maier, L. L. Laursen
TOXICOLOGY LETTERS
(2022)
Meeting Abstract
Toxicology
J. Van Boxel, O. Darraz, M. B. M. Van Duursen, M. Lamoree, S. Hughes
TOXICOLOGY LETTERS
(2022)
Article
Environmental Sciences
Beate Escher, Marja Lamoree, Jean-Philippe Antignac, Martin Scholze, Matthias Herzler, Timo Hamers, Tina Kold Jensen, Marc Audebert, Francois Busquet, Dieter Maier, Michael Oelgeschlaeger, Maria Joao Valente, Henriette Boye, Sebastian Schmeisser, Gaud Dervilly, Matteo Piumatti, Solene Motteau, Maria Koenig, Kostja Renko, Maria Margalef, Ronan Cariou, Yanying Ma, Andreas Frederik Treschow, Andreas Kortenkamp, Anne Marie Vinggaard
Summary: The European Union's Green Deal aims to address the risk of chemical mixtures to human health by filling the existing gaps in risk assessment and implementing regulatory measures. To tackle this challenge, the PANORAMIX project suggests characterizing real-life mixtures, developing a high-throughput screening strategy, evaluating concern levels for children's development, and creating a web-based interface for risk estimation.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Veronica van Der Schyff, Jiri Kalina, Eva Govarts, Liese Gilles, Greet Schoeters, Argelia Castano, Marta Esteban-Lopez, Jiri Kohoutek, Petr Kukucka, Adrian Covaci, Gudrun Koppen, Lenka Andryskova, Pavel Piler, Jana Klanova, Tina Kold Jensen, Loic Rambaud, Margaux Riou, Marja Lamoree, Marike Kolossa-Gehring, Nina Vogel, Till Weber, Thomas Goen, Catherine Gabriel, Dimosthenis A. Sarigiannis, Amrit Kaur Sakhi, Line Smastuen Haug, Lubica Palkovicova Murinova, Lucia Fabelova, Janja Snoj Tratnik, Darja Mazej, Lisa Melymuk
Summary: This study reports the adverse health effects of various legacy and emerging flame retardants (FRs) on human and environmental health in children from nine European countries. The study detected ten halogenated FRs in blood and four organophosphate FR metabolites in urine samples from 2136 children. The concentrations of FRs were associated with lifestyle factors.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Environmental Sciences
Johan Gustafsson, Jessica Legradi, Marja H. Lamoree, Lillemor Asplund, Pim E. G. Leonards
Summary: This study is the first to focus on the effects of OH-PBDEs at the metabolite level in vivo and uses metabolomics to investigate the metabolic effects of exposure to OH-PBDEs. The results suggest that OH-PBDEs may disrupt energy metabolism, neurotoxicity, and potential immunotoxicity, and different compounds have different metabolic effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Maurice de Jonker, Pim E. G. Leonards, Marja H. Lamoree, Sicco H. Brandsma
Summary: A novel method using AP-MALDI coupled with qTOF-MS was developed for fast-screening analysis of additives in electronics and plastic consumer products. A GNP-doped target plate was developed to simplify sample preparation and increase sample throughput. The method showed high desorption/ionization capability for low molecular weight molecules and identified 56 additives in various products. The identification of certain additives in plastic toys suggests their recycling from electronic waste.
Article
Environmental Sciences
Tim J. H. Jonkers, Peter H. J. Keizers, Frederic Been, Jeroen Meijer, Corine J. Houtman, Imane Al Gharib, Douwe Molenaar, Timo Hamers, Marja H. Lamoree
Summary: The study aimed to identify antimicrobial contaminants in the aquatic environment using effect-directed analysis. Samples of wastewater influent, effluent, and surface water were collected at two study sites and subjected to high-resolution fractionation. Antibiotics bioassay was performed on 80 resulting fractions to determine bioactivity. Suspect and non-targeted identification strategy was guided by bioactive fractions using high-resolution mass spectrometry data. The study successfully identified antibiotic metabolites in the aquatic environment, highlighting the importance of considering the toxic effects of bioactive metabolites in environmental risk assessments.
Article
Environmental Sciences
Daniel M. Figueiredo, Serigne Lo, Esmeralda Krop, Jeroen Meijer, Henry Beeltje, Marja H. Lamoree, Roel Vermeulen
Summary: This study demonstrates that silicone collars can be used to measure environmental exposures of domestic animals, and domestic animals can be used as sentinels for human residential exposure. The simultaneous measurement of polycyclic aromatic hydrocarbons (PAHs) using silicone bands worn by pet cats and their owners showed frequent detection of 9 PAHs in both wristbands and collars. This study provides proof-of-principle data for the use of silicone collars to measure animal exposure and highlights the potential of cats as sentinels for human residential exposure.
ENVIRONMENTAL RESEARCH
(2023)
Editorial Material
Engineering, Environmental
Pablo Gago-Ferrero, Akhgar Ghassabian, Marja Lamoree, Leisa-Maree Toms
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
J. K. H. de Schepper, Y. van Oorschot, R. J. Jaspers, T. Hamers, M. H. Lamoree, P. Behnisch, H. Besselink, C. J. Houtman
Summary: A study in the Netherlands found that per- and polyfluoroalkyl substances (PFAS) are widely present in drinking water and surface water sources and have the potential to disrupt the thyroid hormone system. The study also showed that both chemical analysis and bioassays can be used to measure thyroid hormone-displacing activity in water samples. However, the analyzed PFAS only explained a small percentage of the measured activity, indicating that unknown compounds contribute to the majority of the observed thyroid hormone-displacing activity.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Saada Mohammed, Jacco Koekkoek, Isaac Owusu Afriyie Hodgson, Jacob de Boer, Marja Lamoree
Summary: This study examined the use of silicone wristbands as passive sampling devices to assess insecticide exposure among Ghanaian vegetable farmers. The results showed that silicone wristbands can effectively detect individual insecticide exposures, making them a valuable tool for future exposure studies.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Tim J. H. Jonkers, Corine J. Houtman, Yvonne van Oorschot, Marja H. Lamoree, Timo Hamers
Summary: This study aimed to identify contaminants of emerging concern, such as glucocorticoids and antibiotics, in wastewater effluent, and their potential toxic effects on the receiving environment. The research utilized effect-directed analysis (EDA) to analyze effluent samples from six wastewater treatment plants in the Netherlands. The results revealed the presence of macrolide antibiotics in all samples, which significantly contributed to the antimicrobial activity. Furthermore, it was found that there was a sensitivity gap between the estimated concentrations of glucocorticoid active compounds from the bioassay response and the chemical detection limits.
ENVIRONMENTAL RESEARCH
(2023)
Review
Environmental Sciences
Juliane Hollender, Emma L. Schymanski, Lutz Ahrens, Nikiforos Alygizakis, Frederic Been, Lubertus Bijlsma, Andrea M. Brunner, Alberto Celma, Aurelie Fildier, Qiuguo Fu, Pablo Gago-Ferrero, Ruben Gil-Solsona, Peter Haglund, Martin Hansen, Sarit Kaserzon, Anneli Kruve, Marja Lamoree, Christelle Margoum, Jeroen Meijer, Sylvain Merel, Cassandra Rauert, Pawel Rostkowski, Saer Samanipour, Bastian Schulze, Tobias Schulze, Randolph R. Singh, Jaroslav Slobodnik, Teresa Steininger-Mairinger, Nikolaos S. Thomaidis, Anne Togola, Katrin Vorkamp, Emmanuelle Vulliet, Linyan Zhu, Martin Krauss
Summary: The increasing production and use of chemicals have led to a growing interest in understanding their impact on ecosystems and human health through suspect and non-target screening (NTS). To promote effective implementation of NTS, more harmonisation is needed. The NORMAN Association has prepared a guidance document to provide guidance on conducting high-quality NTS studies and interpreting data while addressing the challenges and pitfalls of these techniques. The document covers various steps of NTS, from sampling and analysis to data evaluation and reporting, and also introduces analytical methods, processing techniques, and databases commonly used in NTS workflows.
ENVIRONMENTAL SCIENCES EUROPE
(2023)
Article
Environmental Sciences
Andrea Bellavia, Runyu Zou, Richelle D. Bjorvang, Kristine Roos, Ylva Sjunnesson, Ida Hallberg, Jan Holte, Anne Pikki, Virissa Lenters, Lutzen Portengen, Jacco Koekkoek, Marja Lamoree, Majorie Van Duursen, Roel Vermeulen, Andres Salumets, Agne Velthut-Meikas, Pauliina Damdimopoulou
Summary: This study investigated the associations between potential endocrine-disrupting chemicals (EDCs) and female fertility. By studying 333 women in fertility clinics in Sweden and Estonia, it was found that chemicals such as methylparaben, di-2-ethylhexyl phthalate (DEHP) metabolites, and per- and polyfluoroalkyl substances (PFAS) are associated with female fertility. In particular, DEHP metabolites and methylparaben showed inverse associations with ovarian sensitivity index (OSI), suggesting that these chemicals may affect ovarian function and fertility in women.
ENVIRONMENTAL RESEARCH
(2023)
Article
Toxicology
Maria Margalef, Jeroen Meijer, Marja Lamoree, Timo Hamers
Summary: Exposure to chemicals can disrupt the thyroid hormone system in humans and animals. Biomonitoring and epidemiological studies can assess the risk, but they often focus on single chemicals or classes of chemicals and neglect the complexity of chemical mixtures. In vivo and in vitro studies using real-life samples are necessary to understand the specific effects of chemical mixtures on the thyroid hormone system.
CURRENT OPINION IN TOXICOLOGY
(2023)