IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes

An information theoretic approach to insulin sensing by human kidney podocytes

(2020) Robert JP. Pope et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo

(2019) Thiago M. Batista et al.   Cell Reports

Human soluble phospholipase A2 receptor is an inhibitor of the integrin-mediated cell migratory response to collagen-I

(2018) Kazunori Watanabe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome

(2018) Viji Nair et al.   KIDNEY INTERNATIONAL

Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress

(2018) Kathryn L. Garner et al.   Scientific Reports

The Evolving Importance of Insulin Signaling in Podocyte Health and Disease

(2018) Abigail C. Lay et al.   Frontiers in Endocrinology

Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression

(2016) Belinda Phipson et al.   Annals of Applied Statistics

Overexpression of FOXO1 ameliorates the podocyte epithelial–mesenchymal transition induced by high glucose in vitro and in vivo

(2016) Mengmeng Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain

(2016) Natalie J. Haywood et al.   DIABETES

Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

(2015) C. Ising et al.   EMBO Molecular Medicine

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Integrative Biology Identifies Shared Transcriptional Networks in CKD

(2014) S. Martini et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Global Analysis Reveals the Complexity of the Human Glomerular Extracellular Matrix

(2014) R. Lennon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Abatacept in B7-1–Positive Proteinuric Kidney Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy

(2014) Tianwei Gu et al.   Clinical Epigenetics

The Importance of Podocyte Adhesion for a Healthy Glomerulus

(2014) Rachel Lennon et al.   Frontiers in Endocrinology

Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes

(2013) E. Jennifer Weil et al.   DIABETES

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

(2013) Loredana Fiorentino et al.   EMBO Molecular Medicine

Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse

(2013) LJ Hale et al.   JOURNAL OF PATHOLOGY

Abatacept in B7-1–Positive Proteinuric Kidney Disease

(2013) Chih-Chuan Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

(2012) A. Rajwani et al.   DIABETES

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

The podocyte cytoskeleton—key to a functioning glomerulus in health and disease

(2011) Gavin I. Welsh et al.   Nature Reviews Nephrology

Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival

(2011) S Ammoun et al.   ONCOGENE

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Urinary excretion of IGFBP-1 and -3 correlates with disease activity and differentiates focal segmental glomerulosclerosis and minimal change disease

(2010) Kirstin Worthmann et al.   GROWTH FACTORS

Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement

(2010) H. Ma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

(2010)   LANCET

Systematic Analysis of a Novel Human Renal Glomerulus-Enriched Gene Expression Dataset

(2010) Maja T. Lindenmeyer et al.   PLoS One

β1 integrin expression by podocytes is required to maintain glomerular structural integrity

(2008) Ambra Pozzi et al.   DEVELOPMENTAL BIOLOGY

Insulin-like growth factor-binding protein-1 in the prediction and development of type 2 diabetes in middle-aged Swedish men

(2008) M. S. Lewitt et al.   DIABETOLOGIA

Integrin β1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

(2007) Keizo Kanasaki et al.   DEVELOPMENTAL BIOLOGY