Article
Anatomy & Morphology
Jiaxin Zou, Xiaofeng Jiang, Jubin Feng, Jiawei Cai, Decan Kong, Wuteng Cao, Hengyu Zhao, Dongyun Zhu, Xiaochun Meng, Jia Ke
Summary: This study investigates the anatomical variations of the branches from the left colic artery (LCA) and middle colic artery (MCA) at the splenic flexure area. The researchers used ultra-thin CT images to track the arteries and found specific patterns of vascular distribution, which could provide more anatomical details for vessel management in surgeries for left-sided colon cancer.
SURGICAL AND RADIOLOGIC ANATOMY
(2022)
Article
Surgery
Bjarte T. Andersen, Bojan V. Stimec, Bjorn Edwin, Airazat M. Kazaryan, Przemyslaw J. Maziarz, Dejan Ignjatovic
Summary: This study evaluated the impact of the position of the middle colic artery (MCA) bifurcation and the trajectory of the accessory MCA on adequate lymphadenectomy in colon cancer surgery. The results showed that a longer MCA bifurcated over or right to superior mesenteric vein, and the accessory MCA was found in 31.3% of models, with its trajectory in proximity to the lower pancreatic border.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Oncology
Tao Zhang, Zijia Song, Yaqi Zhang, Xiaopin Ji, Xiaoqian Jing, Yi Shi, Xi Cheng, Ren Zhao
Summary: The study found no significant differences in clinical and oncologic outcomes between robotic-assisted ASFC and laparoscopic-assisted ASFC, except for operation expenses. Robotic-assisted ASFC showed better distal resection margins, with no significant difference in surgical material expenses between the two groups.
JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Yutaka Shishido, Eisei Mitsuoka, Yuma Tanigawa, Hodaka Ooki, Seiji Shio, Shuichi Monzawa, Masayuki Ishii, Koji Fujimoto
Summary: We present a rare case of duodenal ulcer bleeding from a branch of the middle colic artery (MCA). Careful evaluation of bleeding sites is recommended in patients with refractory upper gastrointestinal bleeding to consider unexpected culprit vessels.
Article
Surgery
Salomone Di Saverio, Kostantinos Stasinos, Weronyka Stupalkowska, Umberto Bracale, Pierpaolo Sileri, Antonio Giuliani, Giuseppe Nigri, Efstratios Kouroumpas, James M. D. Wheeler, Giovanni Domenico Tebala, Francesco Di Marzo, Belinda De Simone, Carlos Pastor Idoate, Nicola De Angelis, Roberto Cirocchi, Patricia Tejedor
Summary: This article presents a modified Deloyers procedure for laparoscopic left extended hemicolectomy, highlighting the importance of anatomical and oncological considerations for a successful primary anastomosis and improved postoperative bowel function.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Surgery
Masanobu Enomoto, Kenji Katsumata, Kenta Kasahara, Tomoya Tago, Naoto Okazaki, Takahiro Wada, Hiroshi Kuwabara, Junichi Mazaki, Tetsuo Ishizaki, Yuichi Nagakawa, Akihiko Tsuchida
Summary: Complete mesocolic excision (CME) has been proven to be beneficial for advanced colon cancer. Laparoscopic (Lap) CME with true central vascular ligation (CVL) for advanced right-sided colon cancer is a viable option in surgical oncology. Our institution has been performing Lap D3/modified CME, which involves dissection of main lymph nodes around the root of the middle colic artery (#223LNs) while preserving the left branch of the artery. The median operating time for Lap D3/modified CME was 289 min, with a median blood loss of 57 ml. No metastasis was found in the dissected lymph nodes, indicating the safety and efficacy of this procedure when performed by a skilled surgical team.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Chi Zhang, Esteban Calderon, Yu Hui Chang, Ga-ram Han, Scott R. Kelley, Amit Merchea, Justin T. Brady, Tonia M. Young-Fadok, David A. Etzioni, Nitin Mishra
Summary: There is no consensus on the surgical management of splenic flexure adenocarcinoma (SFA). A study compared postoperative outcomes between patients who underwent segmental resection (SR) and anatomical resection (AR) for SFA. The results showed no differences in overall or recurrence-free survival between the two groups. Age, American Society of Anesthesiology classification, and tumor stage were predictive of mortality. In conclusion, SR is a viable option for the surgical management of SFA.
AMERICAN JOURNAL OF SURGERY
(2023)
Article
Gastroenterology & Hepatology
Siti Mayuha Rusli, Jeong Min Choo, Tae Hoon Lee, Guglielmo Niccolo Piozzi, Hugo Cuellar-Gomez, Se Jin Baek, Jung Myun Kwak, Jin Kim, Seon Hahn Kim
Summary: This study retrospectively analyzed the surgical outcomes and long-term survival of 47 patients with splenic flexure cancer. The results showed that laparoscopic D3 colectomy, guided by highly skilled surgeons, can achieve acceptable morbidity rate and a good 5-year survival rate.
COLORECTAL DISEASE
(2023)
Article
Gastroenterology & Hepatology
Gilles Manceau, Arnaud Alves, Helene Meillat, Leonor Benhaim, Mehdi Ouaissi, Yves H. Panis, Jean-Jacques Tuech, Bertrand Dousset, Cecile Brigand, Eddy Cotte, Zaher Lakkis, Bogdan Badic, Frederic Marchal, Charles Sabbagh, Momar Diouf, Mehdi Karoui
Summary: This study compared splenic flexure colectomy, left hemicolectomy, and subtotal colectomy in patients with splenic flexure tumor regarding perioperative, histological, and survival outcomes. The results showed that splenic flexure colectomy is safe and oncologically adequate, but the debate is not completely closed.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Gastroenterology & Hepatology
Michael L. Horsey, Andrew D. Sparks, Debra Lai, Aalap Herur-Raman, Matthew Ng, Vincent Obias
Summary: This study compared open and minimally invasive approaches for resecting splenic flexure colon cancer. The findings suggest that minimally invasive surgery is associated with lower risks of adverse outcomes, equivalent oncologic results, and improved short and long-term survival compared to open surgery.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2021)
Article
Emergency Medicine
Nicola De'Angelis, Eloy Espin, Frederic Ris, Filippo Landi, Bertrand Le Roy, Federico Coccolini, Valerio Celentano, Angela Gurrado, Denis Pezet, Giorgio Bianchi, Riccardo Memeo, Giulio C. Vitali, Alejandro Solis, Christine Denet, Salomone Di Saverio, Gian Luigi De'Angelis, Miquel Kraft, Paula Gonzalvez-Guardiola, Aine Stakelum, Fausto Catena, David Fuks, Des C. Winter, Mario Testini, Aleix Martinez-Perez
Summary: This study analyzed the outcomes of 90 patients with splenic flexure carcinomas who underwent emergency surgical resection. The study found that extended right colectomy (ERC) was associated with more postoperative complications, but all surgical alternatives showed similar pathological and long-term outcomes.
WORLD JOURNAL OF EMERGENCY SURGERY
(2021)
Article
Oncology
Xing Huang, Zhigang Xiao, Zhongcheng Huang, Dan Li
Summary: D3 lymph node dissection with preservation of the left colic artery (LCA) alone seems to have limited effect in reducing postoperative anastomotic leakage in rectal cancer surgery. Therefore, we propose a novel procedure of D3 lymph node dissection with preservation of LCA and first sigmoid artery (SA). Further study is needed to validate this technique.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Gastroenterology & Hepatology
Jini Wu, Bo Li, Shiliang Tu, Boan Zheng, Bingchen Chen
Summary: This study compares the outcomes of laparoscopic and open splenic flexure colon cancer surgery and finds that laparoscopic surgery has advantages in reducing intraoperative blood loss and overall complications, without affecting long-term survival outcomes.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2022)
Article
Gastroenterology & Hepatology
K. Iguchi, H. Mushiake, S. Hasegawa, T. Fukushima, M. Numata, H. Tamagawa, M. Shiozawa, N. Yukawa, Y. Rino, M. Masuda
Summary: The study aimed to reveal the vascular branching variation in SFC patients using preoperative 3D-CTAC, showing that different patterns of arterial and venous branching could assist in performing accurate surgical procedures.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shingo Kihira, Johanna T. Fifi, Amish H. Doshi, Dwight Xuan, Puneet Belani
Summary: This report presents a rare case of infundibular dilation at the origin of an accessory middle cerebral artery, with partial vessel wall enhancement along the infundibulum. This is the first case report with such findings.
Review
Anatomy & Morphology
Isaac Cheruiyot, Fiona Nyaanga, Vincent Kipkorir, Jeremiah Munguti, Bernard Ndung'u, Brandon Henry, Roberto Cirocchi, Krzysztof Tomaszewski
Summary: Rouviere's sulcus (RS) is a significant extra-biliary landmark in laparoscopic cholecystectomy (LC) with a high prevalence and two main morphological types. It can serve as a fixed extra-biliary landmark during LC to help prevent iatrogenic bile duct injury.
Letter
Gastroenterology & Hepatology
Giuseppe Lippi, Maria Helena Santos de Oliveira, Brandon Michael Henry
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2021)
Review
Surgery
Roberto Cirocchi, Jutsus Randolph, Isaac Cheruiyot, R. Justin Davies, James Wheeler, Sara Gioia, Pavel Reznitskii, Massimo Lancia, Luigi Carlini, Piergiorgio Fedeli, Salomone di Saverio, Brandon Michael Henry
Summary: This systematic review and meta-analysis aimed to determine the prevalence of sigmoid artery variations in anatomy. The most common origin type was Type 1, while Type 3 was the least common. The number of sigmoid arteries typically ranged from one to five, with three being the most prevalent. Understanding the anatomy of the sigmoid arteries pre-operatively is crucial in avoiding iatrogenic injury.
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND
(2021)
Review
Anatomy & Morphology
Roberto Cirocchi, Isaac Cheruiyot, Brandon Michael Henry, Marco Artico, Sara Gioia, Piergaspare Palumbo, Vincent Kipkorir, Vito D'Andrea, Justus Randolph
Summary: This study provided a comprehensive assessment of the anatomical characteristics of the pyramidalis muscle (PM), revealing that PM is present in approximately 90% of individuals, making it a relatively constant anatomical structure.
SURGICAL AND RADIOLOGIC ANATOMY
(2021)
Article
Critical Care Medicine
David Cooper, Ravi Thiagarajan, Brandon Michael Henry, Jonathan W. Byrnes, Andrew Misfeldt, Jason Frischer, Eileen King, Zhiqian Gao, Peter Rycus, Bradley S. Marino
Summary: This study found that the outcomes of multiple runs of ECMO remain poor. Survival decreases with each additional run. Patients requiring additional runs for pulmonary indications should be considered prime candidates. Renal complications on the first run significantly increase the risk of mortality on subsequent runs.
JOURNAL OF INTENSIVE CARE MEDICINE
(2022)
Letter
Pharmacology & Pharmacy
Giuseppe Lippi, Brandon M. Henry, Fabian Sanchis-Gomar
EUROPEAN JOURNAL OF HOSPITAL PHARMACY
(2022)
Article
Pathology
Brandon Michael Henry, Isaac Cheruiyot, Stefanie W. Benoit, Fabian Sanchis-Gomar, Giuseppe Lippi, Justin Benoit
Summary: Necrosis seems to be the main driver of hospitalization in COVID-19 patients, while apoptosis and necrosis appear to drive ICU admission. Elevated levels of CK-18 are independent predictors of severe disease, and could be useful for risk stratification of COVID-19 patients and assessment of therapeutic efficacy in early-phase clinical trials.
JOURNAL OF CLINICAL PATHOLOGY
(2022)
Article
Medicine, Research & Experimental
Brandon Michael Henry, Justin L. Benoit, James Rose, Maria Helena Santos de Oliveira, Giuseppe Lippi, Stefanie W. Benoit
Summary: This study examined plasma ACE concentration and serum ACE activity in COVID-19 patients and non-COVID-19 sick controls, finding no significant differences between the two groups. Additionally, ACE activity and concentration were not associated with the severity of COVID-19 or inflammatory biomarkers.
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
(2021)
Article
Cardiac & Cardiovascular Systems
Wonshill Koh, Megan Rodts, Ashley Nebbia, Jaclyn Sawyer, Brandon Henry, David S. Cooper
Summary: Patients with cyanotic heart disease are at an increased risk of thrombosis. Aspirin has been the main prophylactic anticoagulation method, but there is prevalent aspirin resistance, especially in neonates. This study found that low birth weight is associated with a higher incidence of aspirin resistance, and inadequate initial dosing is the primary reason for resistance. While there was no significant difference in thrombotic events between resistance and non-resistance groups, the presence of both thrombotic events and aspirin resistance was associated with significantly higher in-hospital mortality.
CARDIOLOGY IN THE YOUNG
(2022)
Letter
Infectious Diseases
Camilla Mattiuzzi, Brandon M. Henry, Giuseppe Lippi
JOURNAL OF INFECTION
(2022)
Article
Cardiac & Cardiovascular Systems
Brandon Michael Henry, Alexis L. Benscoter, Maria Helena Santos de Oliveira, Jens Vikse, Tanya Perry, David S. Cooper
Summary: Extracorporeal Membrane Oxygenation (ECMO) has a reasonable survival rate in children with primary immunodeficiencies (PID) who require respiratory support. The type of immunodeficiency and the decade of support do not affect survival rates. The presence of a pre-ECMO infection or infection during the ECMO run does not impact survival rates. Cardiac, pulmonary, and neurological complications are independently associated with increased mortality.
Article
Hematology
Emmanuel J. Favaloro, Brandon Michael Henry, Giuseppe Lippi
Summary: Antiphospholipid antibodies (aPL) reflect a potential prothrombotic risk in several autoimmune conditions, especially antiphospholipid syndrome (APS). While various aPL have been found in COVID-19 patients, most identified solid-phase aPL have low titers and cannot be well-linked to the thrombotic aspects of COVID-19. High-titer or multiple aPL positivity is rare in COVID-19 presentations, suggesting a limited presence of APS in COVID-19 patients.
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2022)
Article
Hematology
Emmanuel J. Favaloro, Brandon Michael Henry, Giuseppe Lippi
Summary: The presence of lupus anticoagulant (LA) in COVID-19 patients is potentially related to the severity of infection, but the relationship between LA and COVID-19-associated coagulopathy needs to be further investigated. Many confounders, such as anticoagulant therapy and elevated CRP levels, may affect the identification of LA. Larger and better studies are needed to clarify the role of LA in COVID-19 pathology.
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2022)
Article
Medicine, General & Internal
Giuseppe Lippi, Riccardo Nocini, Camilla Mattiuzzi, Brandon Michael Henry
Summary: The current strategy of mass screening body temperature has several drawbacks, such as a high rate of asymptomatic infections, difficulty in defining normal body temperature, and device inaccuracy.
Article
Endocrinology & Metabolism
Brandon M. Henry, Ivan Szergyuk, Maria Helena Santos de Oliveira, Mohammed Fawzi Abosamak, Stefanie W. Benoit, Justin L. Benoit, Giuseppe Lippi
Summary: The study found that COVID-19 patients commonly have hypolipidemia, with decreased levels of apo A1 and apo B. Lower LDL-C is associated with the development of severe AKI. Hypolipidemia is correlated with elevated levels of inflammatory biomarkers, potentially related to disrupted fibrinolysis and secondary thrombotic microangiopathy-like processes.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2021)