Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 203, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.colsurfb.2021.111764
Keywords
Nanoemulsion; Drug carrier; Nanoparticle; Nanocapsule; Miniemulsion
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This article discusses the different possibilities of using nanoemulsions to prepare biomedical nanocarriers, including polymeric, inorganic, or hybrid materials. The main synthetic strategies for each type include miniemulsion polymerization, nanoemulsion-solvent evaporation, spontaneous emulsification, sol-gel processes, and a combination of different techniques to form multicomponent materials.
Nanoemulsions are kinetically stabilized emulsions with droplet sizes in the nanometer scale. These nanodroplets are able to confine spaces in which reactions of polymerization or precipitation can take place, leading to the formation of particles and capsules that can act as nanocarriers for biomedical applications. This review discusses the different possibilities of using nanoemulsions for preparing biomedical nanocarriers. According to the chemical nature, nanocarriers prepared in nanoemulsions are classified in polymeric, inorganic, or hybrid. The main synthetic strategies for each type are revised, including miniemulsion polymerization, nanoemulsion-solvent evaporation, spontaneous emulsification, sol-gel processes, and combination of different techniques to form multicomponent materials.
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