Germline Cancer Susceptibility Gene Testing in Unselected Patients With Colorectal Adenocarcinoma: A Multicenter Prospective Study

Olaparib for Metastatic Castration-Resistant Prostate Cancer

(2020) Johann de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Risk for breast cancer and management of unaffected individuals with non‐BRCA hereditary breast cancer

(2020) Marie E. Wood et al.   Breast Journal

Pathologic complete response in patient with ATM mutation after neoadjuvant FOLFOXIRI plus panitumumab therapy for locally-advanced colon cancer, a case report

(2020) Erin McGillivray et al.   Clinical Colorectal Cancer

Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer

(2020) Thierry André et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome

(2020) N. Jewel Samadder et al.   JAMA Oncology

Prognostic impact of ATM mutations in patients with metastatic colorectal cancer

(2019) Giovanni Randon et al.   Scientific Reports

Hereditary Cancer Syndromes—A Primer on Diagnosis and Management, Part 2: Gastrointestinal Cancer Syndromes

(2019) N. Jewel Samadder et al.   MAYO CLINIC PROCEEDINGS

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

(2019) Talia Golan et al.   NEW ENGLAND JOURNAL OF MEDICINE

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019

(2019) Samir Gupta et al.   Journal of the National Comprehensive Cancer Network

Impact of free cancer predisposition cascade genetic testing on uptake in Singapore

(2019) Eliza Courtney et al.   npj Genomic Medicine

Low rates of cascade genetic testing among families with hereditary gynecologic cancer: An opportunity to improve cancer prevention

(2019) Natalie E. Griffin et al.   GYNECOLOGIC ONCOLOGY

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

(2019) Sabrina Arena et al.   CLINICAL CANCER RESEARCH

Germline Genetic Features of Young Individuals With Colorectal Cancer

(2018) Elena M. Stoffel et al.   GASTROENTEROLOGY

Prevalence and properties of intragenic copy-number variation in Mendelian disease genes

(2018) Rebecca Truty et al.   GENETICS IN MEDICINE

Prevalence of germline genetic alterations in colorectal cancer patients.

(2018) Andrea Cercek et al.   JOURNAL OF CLINICAL ONCOLOGY

Cascade Genetic Testing of Relatives for Hereditary Cancer Risk: Results of an Online Initiative

(2018) Jennifer L Caswell-Jin et al.   JNCI-Journal of the National Cancer Institute

Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?

(2018) Peter D. Beitsch et al.   JOURNAL OF CLINICAL ONCOLOGY

Sherloc: a comprehensive refinement of the ACMG–AMP variant classification criteria

(2017) Keith Nykamp et al.   GENETICS IN MEDICINE

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing

(2017) Diana Mandelker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

(2017) Matthew B. Yurgelun et al.   JOURNAL OF CLINICAL ONCOLOGY

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial

(2017) Eric Pujade-Lauraine et al.   LANCET ONCOLOGY

Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation

(2017) Mark Robson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population

(2016) Noriyasu Chika et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein

(2016) Francois Ghiringhelli et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Development and analytical validation of a 25-gene next generation sequencing panel that includes the BRCA1 and BRCA2 genes to assess hereditary cancer risk

(2015) Thaddeus Judkins et al.   BMC CANCER

The APC I1307K allele conveys a significant increased risk for cancer

(2015) Ari Leshno et al.   INTERNATIONAL JOURNAL OF CANCER

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

(2015) Stephen E. Lincoln et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Combined olaparib and oxaliplatin inhibits tumor proliferation and induces G2/M arrest and γ-H2AX foci formation in colorectal cancer

(2015) Kaiwu Xu et al.   OncoTargets and Therapy

Clinical Evaluation of a Multiple-Gene Sequencing Panel for Hereditary Cancer Risk Assessment

(2014) Allison W. Kurian et al.   JOURNAL OF CLINICAL ONCOLOGY

Spectrum and Risk of Neoplasia in Werner Syndrome: A Systematic Review

(2013) Julia M. Lauper et al.   PLoS One

Accurate and exact CNV identification from targeted high-throughput sequence data

(2011) Alex S Nord et al.   BMC GENOMICS

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer

(2011) Lucía Pérez-Carbonell et al.   GUT

Risk of Breast Cancer in Women With a CHEK2 Mutation With and Without a Family History of Breast Cancer

(2011) Cezary Cybulski et al.   JOURNAL OF CLINICAL ONCOLOGY

Sharing Genetic Test Results in Lynch Syndrome: Communication With Close and Distant Relatives

(2008) Elena M. Stoffel et al.   Clinical Gastroenterology and Hepatology