Capturing human trophoblast development with naive pluripotent stem cells in vitro

Derivation of trophoblast stem cells from naïve human pluripotent stem cells

(2020) Chen Dong et al.   eLife

Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells

(2020) Insoo Hyun et al.   Stem Cell Reports

The moral status of human embryo‐like structures: potentiality matters?

(2020) Tsutomu Sawai et al.   EMBO REPORTS

Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome

(2020) Jessica K. Cinkornpumin et al.   Stem Cell Reports

Establishment of porcine and human expanded potential stem cells

(2019) Xuefei Gao et al.   NATURE CELL BIOLOGY

Reconstituting the transcriptome and DNA methylome landscapes of human implantation

(2019) Fan Zhou et al.   NATURE

Controlled modelling of human epiblast and amnion development using stem cells

(2019) Yi Zheng et al.   NATURE

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

In vitro culture of cynomolgus monkey embryos beyond early gastrulation

(2019) Huaixiao Ma et al.   SCIENCE

A developmental landscape of 3D-cultured human pre-gastrulation embryos

(2019) Lifeng Xiang et al.   NATURE

Derivation of Human Trophoblast Stem Cells

(2018) Hiroaki Okae et al.   Cell Stem Cell

Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

(2018) Cheryl Q. E. Lee et al.   DEVELOPMENT

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast

(2018) Giuliano G. Stirparo et al.   DEVELOPMENT

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Placentation defects are highly prevalent in embryonic lethal mouse mutants

(2018) Vicente Perez-Garcia et al.   NATURE

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta

(2018) Sandra Haider et al.   Stem Cell Reports

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

Trophoblast organoids as a model for maternal–fetal interactions during human placentation

(2018) Margherita Y. Turco et al.   NATURE

GENCODE reference annotation for the human and mouse genomes

(2018) Adam Frankish et al.   NUCLEIC ACIDS RESEARCH

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Human trophoblast stem cells: Real or not real?

(2017) Ching-Wen Chang et al.   PLACENTA

The cytotrophoblastic shell and complications of pregnancy

(2017) Graham J. Burton et al.   PLACENTA

RNA-seq reveals conservation of function among the yolk sacs of human, mouse, and chicken

(2017) Tereza Cindrova-Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys

(2017) Tomonori Nakamura et al.   Scientific Data

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

Molecular Criteria for Defining the Naive Human Pluripotent State

(2016) Thorold W. Theunissen et al.   Cell Stem Cell

Human amnion epithelial cells expressing HLA-G as novel cell-based treatment for liver disease

(2016) Stephen C. Strom et al.   HUMAN IMMUNOLOGY

Self-organization of the in vitro attached human embryo

(2016) Alessia Deglincerti et al.   NATURE

A developmental coordinate of pluripotency among mice, monkeys and humans

(2016) Tomonori Nakamura et al.   NATURE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

(2016) Ge Guo et al.   Stem Cell Reports

What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

(2016) Cheryl Q.E. Lee et al.   Stem Cell Reports

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

(2015) P. Blakeley et al.   DEVELOPMENT

SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression

(2015) Tomonori Nakamura et al.   NUCLEIC ACIDS RESEARCH

Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure

(2015) Ying Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas

(2015) Matthias S. Roost et al.   Stem Cell Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Developmental differences in the expression of FGF receptors between human and mouse embryos

(2014) T. Kunath et al.   PLACENTA

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4

(2013) M. Amita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Siglec-6 is expressed in gestational trophoblastic disease and affects proliferation, apoptosis and invasion

(2012) Kristen K Rumer et al.   ENDOCRINE-RELATED CANCER

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

(2011) Andreia S. Bernardo et al.   Cell Stem Cell

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

Vitrification and transfer of cynomolgus monkey (Macaca fascicularis) embryos fertilized by intracytoplasmic sperm injection

(2011) J. Yamasaki et al.   THERIOGENOLOGY

The Transcription Factor TCFAP2C/AP-2  Cooperates with CDX2 To Maintain Trophectoderm Formation

(2010) P. Kuckenberg et al.   MOLECULAR AND CELLULAR BIOLOGY

Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage

(2010) Connie C Wong et al.   NATURE BIOTECHNOLOGY

Regulation of early trophoblast differentiation – Lessons from the mouse

(2010) C.E. Senner et al.   PLACENTA

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols