Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin

(2021) Christopher Michael Hoover et al.   BLOOD

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

(2020) Carsten Deppermann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet life span

(2019) Irene Marini et al.   HAEMATOLOGICA

Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells

(2017) Yun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycans and the platelet life cycle

(2016) Renhao Li et al.   PLATELETS

Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance

(2016) Karin M. Hoffmeister et al.   THROMBOSIS RESEARCH

Novel mechanisms of platelet clearance and thrombopoietin regulation

(2015) Renata Grozovsky et al.   CURRENT OPINION IN HEMATOLOGY

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

(2015) June Li et al.   Nature Communications

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling

(2014) Renata Grozovsky et al.   NATURE MEDICINE

Platelet ITAM signaling is critical for vascular integrity in inflammation

(2013) Yacine Boulaftali et al.   JOURNAL OF CLINICAL INVESTIGATION

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

(2013) Brett H. Herzog et al.   NATURE

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

(2013) Connie H Y Wong et al.   NATURE IMMUNOLOGY

CLEC4F Is an Inducible C-Type Lectin in F4/80-Positive Cells and Is Involved in Alpha-Galactosylceramide Presentation in Liver

(2013) Chih-Ya Yang et al.   PLoS One

Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor

(2013) P. K. Grewal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway

(2013) Binggang Xiang et al.   Nature Communications

Role of sialic acid for platelet life span: exposure of  -galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes

(2009) A. L. Sorensen et al.   BLOOD

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

(2009) Viktoria Rumjantseva et al.   NATURE MEDICINE

The Ashwell receptor mitigates the lethal coagulopathy of sepsis

(2008) Prabhjit K Grewal et al.   NATURE MEDICINE