SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling

Low-level overexpression of p53 promotes warfarin-induced calcification of porcine aortic valve interstitial cells by activatingSluggene transcription

(2018) Li Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The lysine methyltransferase SMYD2 methylates the kinase domain of type II receptor BMPR2 and stimulates bone morphogenetic protein signaling

(2017) Shuman Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMOC can act as both an antagonist and an expander of BMP signaling

(2017) J Terrig Thomas et al.   eLife

BMP signaling turns up in fragile X syndrome: FMRP represses BMPR2

(2016) Heather T. Broihier   Science Signaling

BMP signaling turns up in fragile X syndrome: FMRP represses BMPR2

(2016) Heather T. Broihier   Science Signaling

Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis

(2015) Khader Awwad et al.   CARDIOVASCULAR RESEARCH

The unique activity of bone morphogenetic proteins in bone: a critical role of the Smad signaling pathway

(2013) Takenobu Katagiri et al.   BIOLOGICAL CHEMISTRY

Comparative study of human aortic and mitral valve interstitial cell gene expression and cellular function

(2013) Wei Sun et al.   GENOMICS

Vitamin D and Vascular Calcification in Chronic Kidney Disease

(2011) Mariano Rodriguez et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice

(2011) Joe Rainger et al.   PLoS Genetics

SMOC1 Is Essential for Ocular and Limb Development in Humans and Mice

(2010) Ippei Okada et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in the SPARC-Related Modular Calcium-Binding Protein 1 Gene, SMOC1, Cause Waardenburg Anophthalmia Syndrome

(2010) Hana Abouzeid et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves

(2010) Elaine E. Wirrig et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Secretome Analysis of Human BMSCs and Identification of SMOC1 as an Important ECM Protein in Osteoblast Differentiation

(2010) Young-Ae Choi et al.   JOURNAL OF PROTEOME RESEARCH

Bone morphogenetic protein receptors and signal transduction

(2009) K. Miyazono et al.   JOURNAL OF BIOCHEMISTRY

XenopusSMOC-1 Inhibits Bone Morphogenetic Protein Signaling Downstream of Receptor Binding and Is Essential for Postgastrulation Development inXenopus

(2009) J. Terrig Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2

(2009) Xiaoping Yang et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY