Article
Medicine, General & Internal
David M. Nathan, GRADE Study Res Grp, John M. Lachin, Ashok Balsubramanyam, Henry B. Burch, John B. Buse, Nicole M. Butera, Robert M. Cohen, Jill P. Crandall, Steven E. Kahn, Heidi Krause-Steinrauf, Mary E. Larkin, Neda Rasouli, Margaret Tiktin, Deborah J. Wexler, Naji Younes
Summary: In this trial, all four glucose-lowering medications added to metformin were effective in reducing glycated hemoglobin levels. Glargine and liraglutide showed modestly superior efficacy in achieving and maintaining target glycated hemoglobin levels.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Endocrinology & Metabolism
Miranda T. Schram, Willem J. J. Assendelft, Theo G. van Tilburg, Nicole H. T. M. Dukers-Muijrers
Summary: Social networks have been causally related to disease and mortality risk for decades, but research in this field for diabetes care is still in its early stages. Studies have found that living alone and lack of social support are associated with increased risk of type 2 diabetes, while social support has a positive impact on self-management of diabetes.
Review
Endocrinology & Metabolism
Nicholas J. Wareham
Summary: This review examines the degree of personalization in existing interventions for preventing type 2 diabetes and suggests ways to achieve greater personalization through better identification of high-risk individuals, subdivision of type 2 diabetes into specific subgroups, and individualization of preventive targets. The use of more dynamic real-time data shows promise but requires further evaluation against clinical outcomes. Future personalized preventive approaches should complement existing individual-level interventions and align with strategies at the societal level.
Review
Medicine, General & Internal
Jaakko Tuomilehto, Matti Uusitupa, Edward W. W. Gregg, Jaana Lindstrom
Summary: Several randomized controlled trials have demonstrated the effectiveness of lifestyle interventions in preventing type 2 diabetes (T2D) in high-risk individuals. The national T2D prevention plan in Finland, implemented in 2000, has successfully decreased the incidence of drug-treated T2D. The United States has also authorized a national diabetes prevention program (NDPP) that relies on primary care referrals and self-referrals.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Integrative & Complementary Medicine
Jingying Liu, Chun Yao, Yitao Wang, Jinmin Zhao, Hua Luo
Summary: Traditional Chinese medicine (TCM) has potential for preventing and managing type 2 diabetes through nonpharmacological interventions such as healthy diet, physical activity, emotional therapy, and acupuncture. Studies have shown significant improvement in blood glucose status for prediabetes and type 2 diabetes patients after TCM non-drug interventions. However, the methodological quality of clinical trials involving TCM is generally low and further exploration is needed to validate its effectiveness and underlying mechanism for preventing type 2 diabetes.
Review
Medicine, General & Internal
Ehtasham Ahmad, Soo Lim, Roberta Lamptey, David R. Webb, Melanie J. Davies
Summary: Type 2 diabetes accounts for nearly 90% of global diabetes cases, with an increasing number of affected individuals, particularly among young people. Early detection and proactive management are crucial for preventing complications and reducing mortality. Technology and precision medicine offer potential improvements to treatment outcomes but face significant barriers.
Review
Biochemistry & Molecular Biology
Leila Ismail, Huned Materwala, Juma Al Kaabi
Summary: Diabetes is a leading cause of severe health complications and death globally, with no cure available, requiring preventive measures. This systematic review identifies major risk factors for type 2 diabetes incidence/prevalence and analyzes their impact on the disease. Insights and recommendations are provided for better diagnosis and prognosis, targeting healthcare professionals, individuals, and government institutions.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Review
Food Science & Technology
Diana A. Diaz-Rizzolo, Anna Miro, Ramon Gomis
Summary: Studies have shown that nutritional education and weight control are the best methods to prevent T2D, but the risk of malnutrition should be taken into consideration for the elderly. Oily fish rich in omega-3 and taurine, like sardines, may have a protective effect in slowing down the progression of T2D.
FOOD REVIEWS INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Kirthi Menon, Barbora de Courten, Dianna J. Magliano, Zanfina Ademi, Danny Liew, Ella Zomer
Summary: This study assessed the cost-effectiveness of daily 1g carnosine supplementation in addition to standard care for the management of type 2 diabetes and compared it to standard care alone. The results showed that supplemental dietary carnosine may be a cost-effective treatment option for people with type 2 diabetes in Australia.
Review
Endocrinology & Metabolism
Matthew Retnakaran, Luciana V. Viana, Caroline K. Kramer
Summary: A systematic review found that lifestyle intervention can reduce the risk of type 2 diabetes (T2D) in women with previous gestational diabetes (GD). However, caution is needed when interpreting this finding due to the presence of publication bias.
DIABETES OBESITY & METABOLISM
(2023)
Review
Endocrinology & Metabolism
Laura Pyle, Megan M. Kelsey
Summary: Globally, the proportion of youth-onset type 2 diabetes diagnoses is on the rise, with patients commonly experiencing complications and comorbidities, characterized by pathophysiological heterogeneity and inadequate glycemic control, indicating the need for new treatment approaches and innovative study designs.
Review
Biochemistry & Molecular Biology
Cristina Rey-Renones, Jose Miguel Baena-Diez, Isabel Aguilar-Palacio, Cristina Miquel, Maria Grau
Summary: Individuals with type 2 diabetes are at higher risk for developing and dying from cancer, possibly due to metabolic abnormalities such as obesity. Understanding this link can aid in designing personalized preventive strategies.
Article
Public, Environmental & Occupational Health
Lisa T. Crummett, Muhammad H. Aslam
Summary: The study examines the use of specific terms related to causes/risk factors and preventions for type 2 diabetes on diabetes websites and finds that dietary factors are mentioned less frequently, indicating a need for increased emphasis on dietary information to improve public awareness of type 2 diabetes.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Food Science & Technology
Fanling Liu, Sameera Sirisena, Ken Ng
Summary: A systematic review and meta-analysis of 28 randomized controlled trials found that flavonoid intake can significantly reduce fasting blood glucose, hemoglobin A1c, and other biomarkers related to Type 2 diabetes mellitus. Flavonoid intake has modest but statistically significant benefits in glucose metabolism, insulin sensitivity, and lipid metabolism.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Cardiac & Cardiovascular Systems
Michelle D. Kelsey, Adam J. Nelson, Jennifer B. Green, Christopher B. Granger, Eric D. Peterson, Darren K. McGuire, Neha J. Pagidipati
Summary: Cardiovascular disease is a major concern for individuals with type 2 diabetes mellitus, and aggressive risk factor management is crucial for these high-risk patients. Recommendations and guidelines from professional societies in cardiology, endocrinology, nephrology, and general medicine in the United States and Europe provide guidance on cardiovascular risk reduction for patients with type 2 diabetes mellitus. While there are some differences in risk stratification, treatment targets for low-density lipoprotein-cholesterol and blood pressure, as well as the use of specific medications, overall there is significant alignment across recommendations from different professional societies.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Nursing
Katelyn Sushko, Holly Tschirhart Menezes, Patricia Strachan, Michelle Butt, Diana Sherifali
Summary: This scoping review aimed to synthesize evidence on prenatal diabetes education and support for women with type 1 and type 2 diabetes. The findings showed that education focused on self-management skills and support, and was mainly delivered through one-on-one outpatient appointments every one to three weeks. Many studies used a multidisciplinary team approach, involving physicians, nurses, dietitians, and midwives.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Meeting Abstract
Endocrinology & Metabolism
Natalia Mcinnes, Stephanie Hall, Heather A. Lochnan, Stewart B. Harris, Zubin Punthakee, Ronald J. Sigal, Irene Hramiak, Mohammed Azharuddin, Joanne F. Liutkus, Jean-Francois Yale, Farah Sultan, Ada C. Smith, Rose E. Otto, Diana Sherifali, Yan Yun Liu, Hertzel C. Gerstein
Article
Public, Environmental & Occupational Health
Parminder Raina, Muhammad Usman Ali, Divya Joshi, Anne Gilsing, Alexandra Mayhew, Jinhui Ma, Diana Sherifali, Mary Thompson, Lauren E. Griffith
Summary: This study aimed to explore the clustering of behavioural risk factors and their association with functional disability, finding that physical activity plays a key role in reducing disability burden. The analysis highlights the importance of considering age and sex in tailoring public health strategies to address disability among aging populations.
PREVENTIVE MEDICINE
(2021)
Review
Nutrition & Dietetics
Dipika Desai, Sujane Kandasamy, Jayneel Limbachia, Michael A. Zulyniak, Paul Ritvo, Diana Sherifali, Gita Wahi, Sonia S. Anand, Russell J. de Souza
Summary: South Asians have higher rates of cardiovascular disease, with nutrition playing a critical role in fetal development and early life health. Gestational diabetes is a strong risk factor for both mothers and their offspring, with challenges in non-pharmacological trials to prevent it.
Review
Geriatrics & Gerontology
M. Racey, M. Markle-Reid, D. Fitzpatrick-Lewis, M. U. Ali, H. Gagne, S. Hunter, J. Ploeg, R. Sztramko, L. Harrison, R. Lewis, M. Jovkovic, D. Sherifali
Summary: This review found that many studies did not fully report various aspects of fall prevention interventions, especially in terms of implementation and maintenance.
Article
Endocrinology & Metabolism
Alice Y. Y. Cheng, Denice S. Feig, Josephine Ho, Rick Siemens, Harpreet Bajaj, Jeremy Gilbert, Robyn Houlden, James Kim, Dylan Mackay, Doreen M. Rabi, Peter Senior, Diana Sherifali
CANADIAN JOURNAL OF DIABETES
(2021)
Article
Medicine, Research & Experimental
Dee Mangin, Larkin Lamarche, Gina Agarwal, Hoan Linh Banh, Naomi Dore Brown, Alan Cassels, Kiska Colwill, Lisa Dolovich, Barbara Farrell, Scott Garrison, James Gillett, Lauren E. Griffith, Anne Holbrook, Jane Jurcic-Vrataric, James McCormack, Daria O'Reilly, Parminder Raina, Julie Richardson, Cathy Risdon, Mat Savelli, Diana Sherifali, Henry Siu, Jean-Eric Tarride, Johanna Trimble, Abbas Ali, Karla Freeman, Jessica Langevin, Jenna Parascandalo, Jeffrey A. Templeton, Steven Dragos, Sayem Borhan, Lehana Thabane
Summary: This study aims to test the effect of TAPER, a clinical pathway for reducing inappropriate polypharmacy in older adults, while considering the patient's priorities and preferences.
Review
Geriatrics & Gerontology
Everson A. Nunes, Lauren Colenso-Semple, Sean R. McKellar, Thomas Yau, Muhammad Usman Ali, Donna Fitzpatrick-Lewis, Diana Sherifali, Claire Gaudichon, Daniel Tome, Philip J. Atherton, Maria Camprubi Robles, Sandra Naranjo-Modad, Michelle Braun, Francesco Landi, Stuart M. Phillips
Summary: A systematic review and meta-analysis showed that increasing daily protein ingestion may contribute to gains in lean body mass (LBM) and muscle strength, especially in subjects participating in resistance exercise training. However, the effects on handgrip strength and physical function test performance are unclear.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Geriatrics & Gerontology
A. L. Lorbergs, J. C. Prorok, J. Holroyd-Leduc, D. R. Bouchard, A. Giguere, L. Gramlich, H. Keller, A. Tang, M. Racey, M. U. Ali, D. Fitzpatrick-Lewis, D. Sherifali, P. Kim, John Muscedere
Summary: Moderate improvements in mobility can be achieved through nutritional strategies that optimize dietary intake, various types of physical activity interventions, and interventions that combine nutrition and physical activity. Multi-component physical activity interventions are effective in improving frailty status. Strong recommendations include optimizing dietary intake, performing physical activity, and adopting interventions that combine nutrition and physical activity.
JOURNAL OF FRAILTY & AGING
(2022)
Meeting Abstract
Endocrinology & Metabolism
H. Gerstein, S. Hall, I. Hramiak, R. J. Sigal, R. Goldenberg, N. Gupta, R. Rabasa-Lhoret, M. Braga, V. Woo, F. Sultan, R. Otto, A. Smith, D. Sherifali, Y. Y. Liu, N. McInnes
Meeting Abstract
Endocrinology & Metabolism
N. McInnes, S. Hall, H. Lochnan, S. Harris, Z. Punthakee, R. J. Sigal, I. Hramiak, M. Azharuddin, J. Liutkus, J. -F. Yale, F. Sultan, A. Smith, D. Sherifali, Y. Y. Liu, H. Gerstein
Article
Nursing
Melissa Northwood, Jenny Ploeg, Maureen Markle-Reid, Diana Sherifali
Summary: This study examined how nurses care for older home-care clients with diabetes and incontinence. Findings suggest that nursing interventions should not only focus on disease management but also take into consideration broader social determinants of health in the context of multiple chronic conditions.
Article
Nursing
Melissa Northwood, Jenny Ploeg, Maureen Markle-Reid, Diana Sherifali
Summary: Research findings show that over 40% of older adults with diabetes receiving home-care services experience urinary incontinence. They face enduring challenges in managing diabetes, incontinence, multiple chronic conditions, covering care costs, and relying on caregivers in their daily lives.
GLOBAL QUALITATIVE NURSING RESEARCH
(2021)