Off-the-shelf bone marrow-derived mesenchymal stem cell treatment for acute graft-versus-host disease: real-world evidence

Study 275: Updated Expanded Access Program for Remestemcel-L in Steroid-Refractory Acute Graft-versus-Host Disease in Children

(2020) Joanne Kurtzberg et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease

(2020) Joanne Kurtzberg et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Efficacy of MSC for steroid-refractory acute GVHD associates with MSC donor age and a defined molecular profile

(2020) Lotte E. van der Wagen et al.   BONE MARROW TRANSPLANTATION

Treatment and unmet needs in steroid-refractory acute graft-versus-host disease

(2020) Florent Malard et al.   LEUKEMIA

Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease

(2020) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mesenchymal stromal cells for acute graft-versus-host disease: response at 1 week predicts probability of survival

(2019) Antonio Galleu et al.   BRITISH JOURNAL OF HAEMATOLOGY

A Phase 3 Randomized Study of Remestemcel-L versus Placebo Added to Second-Line Therapy in Patients with Steroid-Refractory Acute Graft-versus-Host Disease

(2019) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

FDA Approval Summary: Ruxolitinib for Treatment of Steroid‐Refractory Acute Graft‐Versus‐Host Disease

(2019) Donna Przepiorka et al.   ONCOLOGIST

Children and Adults with Refractory Acute Graft-versus-Host Disease Respond to Treatment with the Mesenchymal Stromal Cell Preparation “MSC-FFM”—Outcome Report of 92 Patients

(2019) Halvard Bonig et al.   Cells

Effective treatment of steroid and therapy-refractory acute graft-versus-host disease with a novel mesenchymal stromal cell product (MSC-FFM)

(2018) Peter Bader et al.   BONE MARROW TRANSPLANTATION

Placenta-Derived Decidua Stromal Cells for Treatment of Severe Acute Graft-Versus-Host Disease

(2018) Olle Ringden et al.   Stem Cells Translational Medicine

Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

(2017) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence

(2016) Mina Rizk et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

A phase 3 randomized trial comparing inolimomab vs usual care in steroid-resistant acute GVHD

(2016) Gérard Socié et al.   BLOOD

Patterns of infection and infection-related mortality in patients with steroid-refractory acute graft versus host disease

(2016) I García-Cadenas et al.   BONE MARROW TRANSPLANTATION

Good responses but high TRM in adult patients after MSC therapy for GvHD

(2016) U Salmenniemi et al.   BONE MARROW TRANSPLANTATION

Low-dose thymoglobulin as second-line treatment for steroid-resistant acute GvHD: an analysis of the JSHCT

(2016) M Murata et al.   BONE MARROW TRANSPLANTATION

Mesenchymal stromal cells from pooled mononuclear cells of multiple bone marrow donors as rescue therapy in pediatric severe steroid-refractory graft-versus-host disease: a multicenter survey

(2016) Z. Kuci et al.   HAEMATOLOGICA

Mesenchymal stromal cells from pooled mononuclear cells of multiple bone marrow donors as rescue therapy in pediatric severe steroid-refractory graft-versus-host disease: a multicenter survey

(2016) Z. Kuci et al.   HAEMATOLOGICA

Mesenchymal Stem Cell Treatment for Steroid Refractory Graft-versus-Host Disease in Children: A Pilot and First Study from Turkey

(2016) Fatih Erbey et al.   Stem Cells International

A Refined Risk Score for Acute Graft-versus-Host Disease that Predicts Response to Initial Therapy, Survival, and Transplant-Related Mortality

(2015) Margaret L. MacMillan et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Bone marrow-derived mesenchymal stem cells (JR-031) for steroid-refractory grade III or IV acute graft-versus-host disease: a phase II/III study

(2015) Kazuo Muroi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Introduction of Transplant Registry Unified Management Program 2 (TRUMP2): scripts for TRUMP data analyses, part I (variables other than HLA-related data)

(2015) Yoshiko Atsuta   INTERNATIONAL JOURNAL OF HEMATOLOGY

Mesenchymal Stromal Cells for Treatment of Acute Steroid-Refractory Graft Versus Host Disease: Clinical Responses and Long-Term Outcome

(2015) Felix von Dalowski et al.   STEM CELLS

Sequential Third-Party Mesenchymal Stromal Cell Therapy for Refractory Acute Graft-versus-Host Disease

(2014) Fermín Sánchez-Guijo et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Validation and refinement of the Disease Risk Index for allogeneic stem cell transplantation

(2014) P. Armand et al.   BLOOD

Clinical Factors Predicting the Response of Acute Graft-versus-Host Disease to Corticosteroid Therapy: An Analysis from the GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation

(2013) Makoto Murata et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Treatment of Graft versus Host Disease with Mesenchymal Stromal Cells: A Phase I Study on 40 Adult and Pediatric Patients

(2013) Martino Introna et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease

(2013) Lynne M. Ball et al.   BRITISH JOURNAL OF HAEMATOLOGY

Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study

(2013) Kazuo Muroi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

First- and Second-Line Systemic Treatment of Acute Graft-versus-Host Disease: Recommendations of the American Society of Blood and Marrow Transplantation

(2012) Paul J. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Efficacy and Safety of Ex Vivo Cultured Adult Human Mesenchymal Stem Cells (Prochymal™) in Pediatric Patients with Severe Refractory Acute Graft-Versus-Host Disease in a Compassionate Use Study

(2010) Vinod K. Prasad et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Endpoints for Clinical Trials Testing Treatment of Acute Graft-versus-Host Disease: A Joint Statement

(2009) Paul J. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Reduced-Intensity Conditioning Regimen Workshop: Defining the Dose Spectrum. Report of a Workshop Convened by the Center for International Blood and Marrow Transplant Research

(2009) Sergio Giralt et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium

(2008) M von Bonin et al.   BONE MARROW TRANSPLANTATION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET