Review
Gastroenterology & Hepatology
Bianca Lascaris, Vincent E. de Meijer, Robert J. Porte
Summary: Liver transplantation is highly successful, but the demand for donor livers exceeds the supply. High-risk donor livers are being used to address this issue, and machine perfusion is being explored as a way to improve graft quality and viability. Additionally, new strategies are being developed to repair damaged livers before transplantation. This review discusses the potential of normothermic machine perfusion to decrease the imbalance between donor liver demand and supply by enabling the repair and regeneration of damaged livers.
JOURNAL OF HEPATOLOGY
(2022)
Editorial Material
Cell Biology
Sandra A. Murray, Elsie C. Spencer, Antentor Hinton Jr
Summary: Preparing for an academic career requires a postdoctoral position to gain advanced research experience and increase independence. It is also crucial to develop other aspects of your academic portfolio to create a competitive faculty application.
TRENDS IN CELL BIOLOGY
(2022)
Article
Medicine, General & Internal
Linda H. Pololi, Vasilia Vasiliou, Kimberly Bloom-Feshbach
Summary: This qualitative study examined how the COVID-19 pandemic affected midcareer research faculty in academic medicine. Results showed that diverse PhD and physician investigators reported increased meaningfulness in work, professionalism, and enhanced relationships during the pandemic, with intrinsic rewards positively associated with vitality, as well as adverse mental health effects. These findings have implications for addressing burnout and retaining investigators in the future.
Article
Medicine, General & Internal
Eraka P. Bath, Kathleen Brown, Christina Harris, Alma Guerrero, Daniel Kozman, Charles C. Flippen, Isla Garraway, Karol Watson, Langston Holly, Sarah M. Godoy, Keith Norris, Gail Wyatt
Summary: Despite the well-documented underrepresentation of minority scientists and clinicians in medicine, particularly among senior faculty ranks, the lack of equitable and individualized mentorship programs remains a barrier to improving diversity and career advancement. The Justice, Equity, Diversity, and Inclusion Academic Mentors (JAM) Council offers a novel approach to leveraging senior underrepresented faculty members' wisdom and experience to promote the promotion, retention, and career satisfaction of early career minority colleagues in academic medicine.
FRONTIERS IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Katherine A. Crichton, Jamie D. Wilson, Andy Ridgwell, Flavia Boscolo-Galazzo, Eleanor H. John, Bridget S. Wade, Paul N. Pearson
Summary: Paleontological reconstructions show that plankton in the deep-dwelling 'twilight zone' during warm periods of the last 66 million years were less abundant and diverse, and lived closer to the surface. This is due to temperature's effect on the rate of organic matter breakdown, which is faster at warmer temperatures. Our study using an Earth system model reveals that anthropogenic warming could have significant impacts on carbon cycling and twilight zone ecology, leading to widespread ecological disruption by 2100 without strong emissions mitigation.
NATURE COMMUNICATIONS
(2023)
Review
Gastroenterology & Hepatology
Scott L. Friedman, Massimo Pinzani
Summary: Steady progress has been made in understanding the pathogenesis and clinical consequences of hepatic fibrosis, but effective antifibrotic drugs are yet to be approved. This article highlights the successes and identifies gaps and unmet needs in both experimental and clinical aspects. Clarifying the mechanisms of fibrosis regression and developing better models will expedite drug development, while improving diagnostics and utilizing digital pathology methods can enhance prognostic information and better quantify therapeutic responses.
Review
Biochemistry & Molecular Biology
Amelia Seifalian, Zeinab Basma, Alex Digesu, Vikram Khullar
Summary: This study critically evaluates the use of polypropylene (PP) pelvic mesh in the treatment of pelvic organ prolapse (POP), and proposes the use of advanced materials as an alternative to PP mesh. Results show that the physical properties of PP mesh, including its viscoelastic properties and lack of tissue integration, contribute to complications. The banning of PP mesh in multiple countries highlights the need for the development of alternative pelvic mesh materials.
Article
Public, Environmental & Occupational Health
Samuel P. Trethewey
Summary: This article reflects on the history of the UK Faculty of Public Health, discussing its role in shaping public health practice and policy and exploring the changes in identity and roles of public health practitioners.
JOURNAL OF PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Minal Patel, Emily M. Donovan, Bethany J. Simard, Barbara A. Schillo
Summary: This study surveyed 1,526 U.S. middle- and high-school teachers and administrators, finding that school e-cigarette policies and trainings can enhance school staff awareness and intervention on student e-cigarette use, playing a crucial role in addressing the issue.
Article
Nutrition & Dietetics
Tatiana Andreyeva, Xiaohan Sun
Summary: Changes in school meal programs have the potential to affect the well-being of millions of American children. By studying the effects of the Community Eligibility Provision (CEP) on various factors, it was found that CEP expansion may benefit at-risk children and contribute to improving equity in educational and health outcomes.
Article
Ophthalmology
Arsalan A. Ali, Muhammad Z. Chauhan, Madison Doty, Tommy Bui, Paul H. Phillips, Ahmed B. Sallam
Summary: The representation of women has increased among ophthalmology faculty, but the representation of URiM individuals, who are affected by discrimination in medicine, has remained largely unchanged. This finding emphasizes the need for continued efforts to enhance diversity in academic ophthalmology.
JAMA OPHTHALMOLOGY
(2023)
Article
Health Care Sciences & Services
Barron H. Lerner, Graham Curtiss-Rowlands
Summary: This paper reviews the history of colorectal cancer (CRC) screening recommendations by the United States Preventive Services Task Force and explores how the Task Force evaluates evidence to reach its conclusions. It highlights the evolution of their recommendations over the years and the factors influencing their decisions. The article emphasizes the importance of considering multiple factors and processes in evidence-based medicine recommendations.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Kelly Holloway, Fiona A. Miller
Summary: This article investigates the regulatory regime for molecular diagnostics in the US, highlighting the key role of private consultants in coverage and reimbursement. The study emphasizes the production of evidence as a critical part of the process and argues that consultants act as regulatory intermediaries, benefiting their clients' financial interests. The article suggests that public policy discussions should reconsider whose interests are represented in the regulatory regime.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Health Care Sciences & Services
Rui Yang Xu, Nilita Sood, Jeffrey Ding, Nadia Khan, Sabeen Tiwana, Javed Siddiqi, Ateeq Rehman, Namirah Jamshed, Faisal Khosa
Summary: This study evaluated the demographic trends of Internal Medicine (IM) faculty in the US, focusing on sex and race/ethnicity diversity. The findings revealed a predominance of White and male physicians in higher academic ranks, despite an increase in the representation of women and racial/ethnic minority IM faculty. The end of affirmative action threatens to perpetuate this trend, potentially impacting patient access and health outcomes.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Review
Psychology, Multidisciplinary
Bettina J. Casad, Christina E. Garasky, Taylor R. Jancetic, Anne K. Brown, Jillian E. Franks, Christopher R. Bach
Summary: There is a national interest in the underrepresentation of women in STEM fields in the United States. However, gender inequality in the social sciences has not received similar attention. Women in the social sciences still experience gender inequities despite their increasing postgraduate degree attainment. This review challenges the notion that gender bias disappears once women achieve equal representation by providing evidence of systemic gender biases faced by women in well-represented social science domains.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Health Care Sciences & Services
Hemali Patel, Amy Hassell, Angela Keniston, Christopher Davis
Summary: This study describes the impact of remote patient monitoring (RPM) on reducing length of stay (LOS) for patients with COVID-19. By using wearable vital sign monitoring devices and smartphone applications, patient data can be monitored in real time with the help of technicians and physicians. The results of the study show a significant reduction in LOS for patients without home oxygen therapy when using RPM.
TELEMEDICINE AND E-HEALTH
(2023)
Editorial Material
Medicine, General & Internal
Julia B. Caton, Shannon K. Martin, Marisha Burden, Zaven Sargsyan, Michelle Brooks, Daniel N. Ricotta
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Susan L. Calcaterra, Eric Grimm, Angela Keniston
Summary: There is an association between opioid prescribing at hospital discharge and future chronic opioid use. This study aimed to externally validate a prediction model to identify hospitalized patients at the highest risk for future chronic opioid therapy. Among the variables assessed, receiving indigent care was least likely to progress to chronic opioid therapy, while receiving opioids at discharge was most strongly associated with progression to chronic opioid therapy.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Angela Keniston, Lauren McBeth, Gopi Astik, Andrew Auerbach, Johanna Busch, Kirsten N. Kangelaris, Shradha A. Kulkarni, Anne S. Linker, Matthew Sakumoto, Luci Leykum, Marisha Burden
Summary: Rapid qualitative analysis, combined with rapid data acquisition, can be used for timely assessments of quality, operational, and research projects in complex healthcare environments. While it is not intended to replace traditional qualitative methods, rapid qualitative analysis is appropriate in certain situations. The application of a framework to guide projects using a rapid qualitative approach can provide structure to the analysis and engender confidence in the findings.
JOINT COMMISSION JOURNAL ON QUALITY AND PATIENT SAFETY
(2023)
Article
Health Care Sciences & Services
Andrew D. Auerbach, Gopi J. Astik, Kevin J. O'Leary, Peter N. Barish, Molly A. Kantor, Katie R. Raffel, Sumant R. Ranji, Stephanie K. Mueller, Sharran N. Burney, Janice Galinsky, Esteban F. Gershanik, Abhishek Goyal, Pooja R. Chitneni, Sarah Rastegar, Armond M. Esmaili, Cynthia Fenton, Anunta Virapongse, Li-Kheng Ngov, Marisha Burden, Angela Keniston, Hemali Patel, Ashwin B. Gupta, Jeff Rohde, Ruby Marr, S. Ryan Greysen, Michele Fang, Pranav Shah, Frances Mao, Farah Kaiksow, David Sterken, Justin J. Choi, Jigar Contractor, Abhishek Karwa, David Chia, Tiffany Lee, Colin C. Hubbard, Judith Maselli, Anuj K. Dalal, Jeffrey L. Schnipper
Summary: Diagnostic errors were common among patients under investigation for COVID-19, and they were not associated with care changes during the pandemic. This suggests that there are general process gaps in the diagnostic process that contribute to error propagation.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Medicine, General & Internal
Lanna Felde, Marisha Burden, Nainesh Shah, Pedro Ramos, Eugene S. S. Chu
Summary: This study examines the current state of hospital medicine fellowships in the United States, focusing on demographics, clinical requirements, curriculum, financial structure, and scholarly outputs. A survey was conducted among 32 fellowship programs, revealing that the majority of programs prioritize research, quality improvement, and medical education.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Shradha A. A. Kulkarni, Angela Keniston, Anne S. S. Linker, Gopi J. J. Astik, Kirsten N. N. Kangelaris, Luci K. K. Leykum, Matthew Sakumoto, Andrew Auerbach, Marisha Burden
Summary: Through qualitative focus groups, we identified current and future workforce concerns for hospitalists and developed strategies to address them. These concerns included focusing on workforce wellness, maintaining an adequate workforce to match clinical growth, defining the scope of work for hospitalists and expanding their clinical skillset, and aligning hospitalist responsibilities with hospital resources. These areas were identified as high-priority areas of focus for current and future challenges.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Marisha Burden, Angela Keniston, Venkat P. P. Gundareddy, Regina Kauffman, Joseph W. W. Keach, Lauren McBeth, Katie E. E. Raffel, John D. D. Rice, Catherine Washburn, Flora Kisuule
Summary: To relieve hospital capacity strain, hospitals often encourage clinicians to prioritize early morning discharges which may have unintended consequences.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Susan L. Calcaterra, Scott Saunders, Eric Grimm, Emma Maki-Gianani, Angela Keniston, Angi Wold, Angela Bonaguidi
Summary: This study describes a federally compliant In-Hospital Methadone Enrollment Team (IN-MEET) that enrolls hospitalized patients with opioid use disorder (OUD) into an opioid treatment program (OTP) and facilitates their transition from hospital to OTP. The results show that IN-MEET is effective in linking older, unhoused patients who primarily use heroin or fentanyl and inject their substances to OTP.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Johanna I. Busch, Angela Keniston, Gopi J. Astik, Andrew Auerbach, Kirsten N. Kangelaris, Shradha A. Kulkarni, Luci K. Leykum, Anne S. Linker, Kirsten Nieto, Read G. Pierce, Matthew Sakumoto, Marisha Burden
Summary: This study shows that the COVID-19 pandemic has had a negative impact on women physicians, exacerbating gender inequities, affecting academic productivity and career development, and increasing caregiving and household responsibilities for women. The researchers propose multiple interventions to improve the workplace conditions for women.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Medicine, General & Internal
Shaker G. Eid, Valerie Press, Hirotaka M. Kato, Valerie M. Vaughn, Ashley Jenkins, Christine Soong, Vineet J. Gupta, Henry Michtalik, Angela Keniston, Marisha Burden, Sanjay K. Bhandari, Stephanie Mueller, Soc Hosp Med Res Comm
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Jeffrey L. Schnipper, Katie E. Raffel, Angela Keniston, Marisha Burden, Jeffrey Glasheen, Sumant Ranji, Colin Hubbard, Peter Barish, Molly Kantor, Julia Adler-Milstein, W. John Boscardin, James D. Harrison, Anuj K. Dalal, Tiffany Lee, Andrew Auerbach
Summary: This study aims to integrate surveillance for diagnostic errors into usual care, benchmark diagnostic performance across hospitals, and implement interventions to reduce diagnostic errors. By monitoring, investigating, and sharing experiences, the study aims to improve patients' diagnostic outcomes.
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Micah Prochaska, Angela Keniston, Marisha Burden, Stephanie Mueller, Valerie M. Vaughn
JOURNAL OF HOSPITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Vishruti Patel, Angela Keniston, Lauren Mcbeth, Sagarika Arogyaswamy, Catherine Callister, Khooshbu Dayton, Neelam Mistry, Sarah Mann, Marisha Burden
Summary: This study aims to understand the impact of clinical growth on the educational mission in academic medical centers. Interviews with HM leaders from 17 large AMCs revealed a tension between clinical and educational missions, a preference for traditional teaching among hospitalists, and a need to reimagine the role and identity of academic hospitalists.
ANNALS OF INTERNAL MEDICINE
(2023)