Developing GLP-1 Conjugated Self-Assembling Nanofibers Using Copper-Catalyzed Alkyne–Azide Cycloaddition and Evaluation of Their Biological Activity

Optimized Methods for the Production and Bioconjugation of Site-Specific, Alkyne-Modified Glucagon-like Peptide-1 (GLP-1) Analogs to Azide-Modified Delivery Platforms Using Copper-Catalyzed Alkyne–Azide Cycloaddition

(2020) Seyed Ebrahim Alavi et al.   BIOCONJUGATE CHEMISTRY

Glucagon-Like Peptide-1 Receptor Agonists and Strategies To Improve Their Efficiency

(2019) Seyed Ebrahim Alavi et al.   MOLECULAR PHARMACEUTICS

Peptide Oligomerization Memory Effects and Their Impact on the Physical Stability of the GLP-1 Agonist Liraglutide

(2019) Jameson R. Bothe et al.   MOLECULAR PHARMACEUTICS

Battle of GLP-1 delivery technologies

(2018) Minzhi Yu et al.   ADVANCED DRUG DELIVERY REVIEWS

Glucagon-Like Peptide-1 (GLP-1)-Based Therapeutics: Current Status and Future Opportunities beyond Type 2 Diabetes

(2018) Jia Ying Cheang et al.   ChemMedChem

Nanoparticles induced by embedding self-assembling cassette into glucagon-like peptide 1 for improving in vivo stability

(2018) Ying Li et al.   FASEB JOURNAL

GLP-1 Receptor Agonist Exendin-4 Attenuates NR4A Orphan Nuclear Receptor NOR1 Expression in Vascular Smooth Muscle Cells

(2018) Hiroyuki Takahashi et al.   Journal of Atherosclerosis and Thrombosis

Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8 + T cell responses

(2018) Youhui Si et al.   JOURNAL OF CONTROLLED RELEASE

Glucagon-like peptide 1 in health and disease

(2018) Andreas Andersen et al.   Nature Reviews Endocrinology

DNA methylation in the pathogenesis of type 2 diabetes in humans

(2018) Cajsa Davegårdh et al.   Molecular Metabolism

Differential engagement of polar networks in the glucagon-like peptide 1 receptor by endogenous variants of the glucagon-like peptide 1

(2018) S.G.B. Furness et al.   BIOCHEMICAL PHARMACOLOGY

Recent updates on GLP-1 agonists: Current advancements & challenges

(2018) Dilip Sharma et al.   BIOMEDICINE & PHARMACOTHERAPY

Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls

(2016) Linlin Sun et al.   International Journal of Nanomedicine

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion

(2015) Guy A. Rutter et al.   BIOCHEMICAL JOURNAL

Beta-Sheet-Forming, Self-Assembled Peptide Nanomaterials towards Optical, Energy, and Healthcare Applications

(2015) Sungjin Kim et al.   Small

Exendin-4, a GLP-1 Receptor Agonist, Attenuates Prostate Cancer Growth

(2014) Takashi Nomiyama et al.   DIABETES

Glucagon-like Peptide-1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic Implications

(2014) Bikash Manandhar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Engineering Fluorogen Activating Proteins into Self-Assembling Materials

(2013) Matthew J. Saunders et al.   BIOCONJUGATE CHEMISTRY

Recent progress and future options in the development of GLP-1 receptor agonists for the treatment of diabesity

(2013) Martin Lorenz et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics

(2013) Miriam Góngora-Benítez et al.   CHEMICAL REVIEWS

Self-Assembling Peptides Improve the Stability of Glucagon-like Peptide-1 by Forming a Stable and Sustained Complex

(2013) Ying Li et al.   MOLECULAR PHARMACEUTICS

Click Chemistry in Peptide-Based Drug Design

(2013) Huiyuan Li et al.   MOLECULES

Peptide lipidation stabilizes structure to enhance biological function

(2013) Brian P. Ward et al.   Molecular Metabolism

Self-assembling peptide-based nanoparticles enhance cellular delivery of the hydrophobic anticancer drug ellipticine through caveolae-dependent endocytosis

(2011) Roli Bawa et al.   Nanomedicine-Nanotechnology Biology and Medicine

Solid-phase synthesis of aromatic polyamide dendrons

(2011) Hiroyuki Tsushima et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening

(2010) C. Koole et al.   MOLECULAR PHARMACOLOGY

Val8-glucagon-like peptide-1 protects against Aβ1–40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats

(2010) X.H. Wang et al.   NEUROSCIENCE

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nutritional regulation of glucagon-like peptide-1 secretion

(2008) Gwen Tolhurst et al.   JOURNAL OF PHYSIOLOGY-LONDON