4.5 Article Book Chapter

Recent Advances in Microfluidically Spun Microfibers for Tissue Engineering and Drug Delivery Applications

Journal

Publisher

ANNUAL REVIEWS
DOI: 10.1146/annurev-anchem-090420-101138

Keywords

microfiber; microfluidic spinning; tissue engineering; drug delivery; cell seeding

Funding

  1. Office of Naval Research [N000141712620]
  2. National Science Foundation [2014346]
  3. Translational Impacts
  4. Dir for Tech, Innovation, & Partnerships [2014346] Funding Source: National Science Foundation
  5. U.S. Department of Defense (DOD) [N000141712620] Funding Source: U.S. Department of Defense (DOD)

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Microfluidically spun microfibers with unique and tunable properties have made significant advancements in the field of biomedical engineering, particularly in tissue engineering, wound dressing, drug delivery, cell encapsulation, and cell seeding. This article analyzes the latest advances in microfluidics and microfibers, focusing on their biomedical applications and exploring new experiments, materials, promises, and limitations. The future work in this area is also discussed in terms of potential applications and advancements that can be made.
In recent years, the unique and tunable properties of microfluidically spun microfibers have led to tremendous advancements for the field of biomedical engineering, which have been applied to areas such as tissue engineering, wound dressing, and drug delivery, as well as cell encapsulation and cell seeding. In this article, we analyze the most recent advances in microfluidics and microfluidically spun microfibers, with an emphasis on biomedical applications. We explore in detail these new and innovative experiments, how microfibers are made, the experimental purpose of making microfibers, and the future work that can be done as a result of these new types of microfibers. We also focus on the applications of various materials used to fabricate microfibers, as well as their many promises and limitations.

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