A Phase II, Multicenter, Randomized, Placebo-Controlled Study of Benralizumab, a Humanized Anti-IL-5R Alpha Monoclonal Antibody, in Patients With Eosinophilic Chronic Rhinosinusitis

Formation of nasal polyps: The roles of innate type 2 inflammation and deposition of fibrin

(2020) Tetsuji Takabayashi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: Asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis

(2020) Hiroyuki Nagase et al.   ALLERGOLOGY INTERNATIONAL

Eosinophilic chronic rhinosinusitis

(2019) Shigeharu Fujieda et al.   ALLERGOLOGY INTERNATIONAL

Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial

(2017) Claus Bachert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Diversity of T H cytokine profiles in patients with chronic rhinosinusitis: A multicenter study in Europe, Asia, and Oceania

(2016) Xiangdong Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers

(2016) Peter Tomassen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial

(2016) Eugene R Bleecker et al.   LANCET

Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial

(2016) J Mark FitzGerald et al.   LANCET

Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study

(2015) T. Tokunaga et al.   ALLERGY

Effect of budesonide transnasal nebulization in patients with eosinophilic chronic rhinosinusitis with nasal polyps

(2015) Chengshuo Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunopathology of chronic rhinosinusitis

(2015) Atsushi Kato   ALLERGOLOGY INTERNATIONAL

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

(2013) Michel Laviolette et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophilic Chronic Rhinosinusitis in Japan

(2010) Junichi Ishitoya et al.   ALLERGOLOGY INTERNATIONAL