Photoporation with Biodegradable Polydopamine Nanosensitizers Enables Safe and Efficient Delivery of mRNA in Human T Cells

ROS-augmented and tumor-microenvironment responsive biodegradable nanoplatform for enhancing chemo-sonodynamic therapy

(2020) Jie An et al.   BIOMATERIALS

Surface Functionalization with Polyethylene Glycol and Polyethyleneimine Improves the Performance of Graphene-Based Materials for Safe and Efficient Intracellular Delivery by Laser-Induced Photoporation

(2020) Jing Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis

(2020) Juan C. Fraire et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation

(2020) Laurens Raes et al.   Nano-Micro Letters

Naive T cell deficits at diagnosis and after chemotherapy impair cell therapy potential in pediatric cancers

(2019) Rajat K Das et al.   Cancer Discovery

The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy

(2019) Jessica B. Foster et al.   MOLECULAR THERAPY

Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells

(2019) Laurens Raes et al.   Crystals

Multi-functional bismuth-doped bioglasses: combining bioactivity and photothermal response for bone tumor treatment and tissue repair

(2018) Liping Wang et al.   Light-Science & Applications

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts

(2018) Martin P. Stewart et al.   CHEMICAL REVIEWS

Reprogramming human T cell function and specificity with non-viral genome targeting

(2018) Theodore L. Roth et al.   NATURE

Electrochemical impedance spectroscopy reveals new mechanism based on competitive binding between Tris and protein on conductive biomimetic polydopamine surface.

(2018) Nimisha Singh et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Degradation Products of Polydopamine Restrained Inflammatory Response of LPS-Stimulated Macrophages Through Mediation TLR-4-MYD88 Dependent Signaling Pathways by Antioxidant

(2018) Liang Jin et al.   INFLAMMATION

Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo

(2018) Tia DiTommaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms

(2018) Eline Teirlinck et al.   Nature Communications

Comparing photoporation and nucleofection for delivery of small interfering RNA to cytotoxic T cells

(2017) Laura Wayteck et al.   JOURNAL OF CONTROLLED RELEASE

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

(2017) James N. Kochenderfer et al.   MOLECULAR THERAPY

Intracellular Fate of Nanoparticles with Polydopamine Surface Engineering and a Novel Strategy for Exocytosis-Inhibiting, Lysosome Impairment-Based Cancer Therapy

(2017) Li Ding et al.   NANO LETTERS

Simple and tunable surface coatings via polydopamine for modulating pharmacokinetics, cell uptake and biodistribution of polymeric nanoparticles

(2017) Jingshuo Liu et al.   RSC Advances

Mimicking Melanosomes: Polydopamine Nanoparticles as Artificial Microparasols

(2017) Yuran Huang et al.   ACS Central Science

Global Manufacturing of CAR T Cell Therapy

(2017) Bruce L. Levine et al.   Molecular Therapy-Methods & Clinical Development

Reshaping, Fragmentation, and Assembly of Gold Nanoparticles Assisted by Pulse Lasers

(2016) Guillermo González-Rubio et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cytosolic Delivery of Nanolabels Prevents Their Asymmetric Inheritance and Enables Extended Quantitative in Vivo Cell Imaging

(2016) Ranhua Xiong et al.   NANO LETTERS

Clinical manufacturing of CAR T cells: foundation of a promising therapy

(2016) Xiuyan Wang et al.   Molecular Therapy-Oncolytics

Comparison of Gold Nanoparticle Mediated Photoporation: Vapor Nanobubbles Outperform Direct Heating for Delivering Macromolecules in Live Cells

(2014) Ranhua Xiong et al.   ACS Nano

Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields

(2014) Yanlan Liu et al.   CHEMICAL REVIEWS

Mussel-inspired polydopamine coated mesoporous silica nanoparticles as pH-sensitive nanocarriers for controlled release

(2014) Qishan Zheng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The impact of Nucleofection® on the activation state of primary human CD4 T cells

(2014) Mingce Zhang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria

(2013) E. Y. Lukianova-Hleb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine-Melanin Colloidal Nanospheres: An Efficient Near-Infrared Photothermal Therapeutic Agent for In Vivo Cancer Therapy

(2012) Yanlan Liu et al.   ADVANCED MATERIALS

Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles

(2012) Ekaterina Y. Lukianova-Hleb et al.   BIOMATERIALS

Bioinspired Polymerization of Dopamine to Generate Melanin-Like Nanoparticles Having an Excellent Free-Radical-Scavenging Property

(2011) Kuk-Youn Ju et al.   BIOMACROMOLECULES

Plasmonic nanobubble-enhanced endosomal escape processes for selective and guided intracellular delivery of chemotherapy to drug-resistant cancer cells

(2011) Ekaterina Y. Lukianova-Hleb et al.   BIOMATERIALS

Selective gene transfection of individual cells in vitro with plasmonic nanobubbles

(2011) Ekaterina Y. Lukianova-Hleb et al.   JOURNAL OF CONTROLLED RELEASE

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plasmonic Nanobubbles as Transient Vapor Nanobubbles Generated around Plasmonic Nanoparticles

(2010) Ekaterina Lukianova-Hleb et al.   ACS Nano

Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor

(2010) Y. Zhao et al.   CANCER RESEARCH

Biocompatibility of biodegradable semiconducting melanin films for nerve tissue engineering

(2009) Christopher J. Bettinger et al.   BIOMATERIALS

Influence of laser parameters on nanoparticle-induced membrane permeabilization

(2009) Cuiping Yao et al.   JOURNAL OF BIOMEDICAL OPTICS

Optical excitation and detection of vapor bubbles around plasmonic nanoparticles

(2009) Dmitri Lapotko   OPTICS EXPRESS

Facile Conjugation of Biomolecules onto Surfaces via Mussel Adhesive Protein Inspired Coatings

(2008) Haeshin Lee et al.   ADVANCED MATERIALS

Modeling Transmembrane Transport through Cell Membrane Wounds Created by Acoustic Cavitation

(2008) Vladimir Zarnitsyn et al.   BIOPHYSICAL JOURNAL