Breaking the Redox Homeostasis: an Albumin‐Based Multifunctional Nanoagent for GSH Depletion‐Assisted Chemo‐/Chemodynamic Combination Therapy

Self-Delivered and Self-Monitored Chemo-Photodynamic Nanoparticles with Light-Triggered Synergistic Antitumor Therapies by Downregulation of HIF-1α and Depletion of GSH

(2020) Zhongtao Zhang et al.   ACS Applied Materials & Interfaces

Fusiform-Like Copper(II)-Based Metal–Organic Framework through Relief Hypoxia and GSH-Depletion Co-Enhanced Starvation and Chemodynamic Synergetic Cancer Therapy

(2020) Zhao Wang et al.   ACS Applied Materials & Interfaces

Fe3O4 Mesocrystals with Distinctive Magnetothermal and Nanoenzyme Activity Enabling Self-Reinforcing Synergistic Cancer Therapy

(2020) Wenxian Du et al.   ACS Applied Materials & Interfaces

Immunomodulation‐Enhanced Nanozyme‐Based Tumor Catalytic Therapy

(2020) Bolong Xu et al.   ADVANCED MATERIALS

Near-Infrared Light Irradiation Induced Mild Hyperthermia Enhances Glutathione Depletion and DNA Interstrand Cross-Link Formation for Efficient Chemotherapy

(2020) Jimei Zhang et al.   ACS Nano

GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy

(2020) Shuming Dong et al.   ADVANCED MATERIALS

GSH depletion liposome adjuvant for augmenting the photothermal immunotherapy of breast cancer

(2020) Zhanwei Zhou et al.   Science Advances

Nanoscale Coordination Polymers for Synergistic NO and Chemodynamic Therapy of Liver Cancer

(2019) Yihui Hu et al.   NANO LETTERS

Clearable Theranostic Platform with a pH-Independent Chemodynamic Therapy Enhancement Strategy for Synergetic Photothermal Tumor Therapy

(2019) Qian Chen et al.   ACS Applied Materials & Interfaces

Ultrasmall Oxygen‐Deficient Bimetallic Oxide MnWO X Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy

(2019) Fei Gong et al.   ADVANCED MATERIALS

A Hypoxia‐Responsive Albumin‐Based Nanosystem for Deep Tumor Penetration and Excellent Therapeutic Efficacy

(2019) Guangbao Yang et al.   ADVANCED MATERIALS

Specifically Generation of Singlet Oxygen via Russell Mechanism in Hypoxic Tumor and GSH Depletion by Cu-TCPP Nanosheets for Cancer Therapy

(2019) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Albumin-Binding T1–T2 Dual-Modal MRI Contrast Agents for Improved Sensitivity and Accuracy in Tumor Imaging

(2019) Zijian Zhou et al.   BIOCONJUGATE CHEMISTRY

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

(2019) Li-Sen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

GSH‐Depleted PtCu 3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy

(2019) Xiaoyan Zhong et al.   ADVANCED FUNCTIONAL MATERIALS

Self‐Supply of O 2 and H 2 O 2 by a Nanocatalytic Medicine to Enhance Combined Chemo/Chemodynamic Therapy

(2019) Shutao Gao et al.   Advanced Science

Biodegradable Manganese-Doped Calcium Phosphate Nanotheranostics for Traceable Cascade Reaction-Enhanced Anti-Tumor Therapy

(2019) Lian-Hua Fu et al.   ACS Nano

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

BSA-IrO2 : Catalase-like Nanoparticles with High Photothermal Conversion Efficiency and a High X-ray Absorption Coefficient for Anti-inflammation and Antitumor Theranostics

(2018) Wenyao Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactive oxygen species-responsive nanoprodrug with quinone methides-mediated GSH depletion for improved chlorambucil breast cancers therapy

(2018) Cheng-Qiong Luo et al.   JOURNAL OF CONTROLLED RELEASE

Drug-induced co-assembly of albumin/catalase as smart nano-theranostics for deep intra-tumoral penetration, hypoxia relieve, and synergistic combination therapy

(2017) Qian Chen et al.   JOURNAL OF CONTROLLED RELEASE

Mitochondria Targeted Protein-Ruthenium Photosensitizer for Efficient Photodynamic Applications

(2017) Sabyasachi Chakrabortty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Facile Ion-Doping Strategy To Regulate Tumor Microenvironments for Enhanced Multimodal Tumor Theranostics

(2017) Jing Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species

(2017) Ping’an Ma et al.   NANO LETTERS

Dual Roles of Protein as a Template and a Sulfur Provider: A General Approach to Metal Sulfides for Efficient Photothermal Therapy of Cancer

(2017) Jianping Sheng et al.   Small

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

(2017) Minfeng Huo et al.   Nature Communications

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

BSA-Mediated Synthesis of Bismuth Sulfide Nanotheranostic Agents for Tumor Multimodal Imaging and Thermoradiotherapy

(2016) Yong Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Copper(II)-Graphitic Carbon Nitride Triggered Synergy: Improved ROS Generation and Reduced Glutathione Levels for Enhanced Photodynamic Therapy

(2016) Enguo Ju et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

(2016) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Iron Nanometallic Glasses and Their Application in Cancer Therapy by a Localized Fenton Reaction

(2016) Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy

(2016) Barbara Marengo et al.   Oxidative Medicine and Cellular Longevity

The potential use of lapatinib-loaded human serum albumin nanoparticles in the treatment of triple-negative breast cancer

(2015) Xu Wan et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of NADPH Oxidases in Cisplatin-Induced Reactive Oxygen Species Generation and Ototoxicity

(2010) H.-J. Kim et al.   JOURNAL OF NEUROSCIENCE