Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress

Analysis of binding affinity and docking of novel fatty acid-binding protein (FABP) ligands

(2020) Yasuharu Shinoda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in Oligodendrocytes

(2020) An Cheng et al.   Biomedicines

Inhibition of MPTP-induced α-synuclein oligomerization by fatty acid-binding protein 3 ligand in MPTP-treated mice

(2019) Kazuya Matsuo et al.   NEUROPHARMACOLOGY

Nitrated alpha-synuclein in minor salivary gland biopsies in Parkinson’s disease

(2019) Ling-Yan Ma et al.   NEUROSCIENCE LETTERS

Astrocyte-derived fatty acid-binding protein 7 protects blood-brain barrier integrity through a caveolin-1/MMP signaling pathway following traumatic brain injury

(2019) Qin Rui et al.   EXPERIMENTAL NEUROLOGY

Human Molecular Chaperone Hsp60 and Its Apical Domain Suppress Amyloid Fibril Formation of α-Synuclein

(2019) Hanae Yamamoto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diagnosis of multiple system atrophy

(2018) Jose-Alberto Palma et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Analysis of age-related changes in psychosine metabolism in the human brain

(2018) Michael S. Marshall et al.   PLoS One

α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies

(2018) Hazem Abdelkarim et al.   Scientific Reports

KY-226 Protects Blood–brain Barrier Function Through the Akt/FoxO1 Signaling Pathway in Brain Ischemia

(2018) Meiling Sun et al.   NEUROSCIENCE

Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization

(2018) An Cheng et al.   BRAIN RESEARCH

Diagnostic utility of cerebrospinal fluid α-synuclein in Parkinson's disease: A systematic review and meta-analysis

(2017) Paolo Eusebi et al.   MOVEMENT DISORDERS

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration

(2017) Hisham Abdelmotilib et al.   NEUROBIOLOGY OF DISEASE

α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy

(2016) Benjamin Ettle et al.   ACTA NEUROPATHOLOGICA

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains

(2016) Rina Bandopadhyay   Jove-Journal of Visualized Experiments

Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-1

(2015) Yoshiteru Kagawa et al.   GLIA

Dehydroascorbic Acid Promotes Cell Death in Neurons Under Oxidative Stress: a Protective Role for Astrocytes

(2015) Andrea García-Krauss et al.   MOLECULAR NEUROBIOLOGY

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

(2015) W. Peelaerts et al.   NATURE

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-synuclein mRNA expression in oligodendrocytes in MSA

(2014) Yasmine T. Asi et al.   GLIA

FABP3 Protein Promotes α-Synuclein Oligomerization Associated with 1-Methyl-1,2,3,6-tetrahydropiridine-induced Neurotoxicity

(2014) Norifumi Shioda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring Myelin Dysfunction in Multiple System Atrophy

(2014) Joanna H. Wong et al.   Experimental Neurobiology

Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands

(2013) Yoko Beniyama et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alpha-synuclein transfers from neurons to oligodendrocytes

(2013) Juan F. Reyes et al.   GLIA

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

(2013) Dusan Roncevic et al.   JOURNAL OF NEURAL TRANSMISSION

Targeting Nitrosative Stress for Neurovascular Protection: New Implications in Brain Diseases

(2012) Rong-Rong Tao et al.   CURRENT DRUG TARGETS

Increased Neuronal α-Synuclein Pathology Associates with Its Accumulation in Oligodendrocytes in Mice Modeling α-Synucleinopathies

(2012) Haya Kisos et al.   PLoS One

The Effects of Fabp7 and Fabp5 on Postnatal Hippocampal Neurogenesis in the Mouse

(2012) Miho Matsumata et al.   STEM CELLS

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple system atrophy: a clinical and neuropathological perspective

(2011) Kiren Ubhi et al.   TRENDS IN NEUROSCIENCES

Brain-specific fatty acid-binding protein is elevated in serum of patients with dementia-related diseases

(2010) C. E. Teunissen et al.   EUROPEAN JOURNAL OF NEUROLOGY

Multiple system atrophy: an update

(2009) Nadia Stefanova et al.   LANCET NEUROLOGY

Exogenous  -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

(2009) K. C. Luk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Motor impairment and aberrant production of neurochemicals in human α-synuclein A30P+A53T transgenic mice with α-synuclein pathology

(2008) Masaki Ikeda et al.   BRAIN RESEARCH

Fatty Acid Binding Protein: Localization and Functional Significance in the Brain

(2008) Yuji Owada   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE