Metabolic Control by Heat Stress Determining Cell Fate to Ferroptosis for Effective Cancer Therapy

Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer

(2021) Ali Ghoochani et al.   CANCER RESEARCH

Reduced Sulfation Enhanced Oxytosis and Ferroptosis in Mouse Hippocampal HT22 Cells

(2020) Haruna Nagase et al.   Biomolecules

Semiconducting Polycomplex Nanoparticles for Photothermal Ferrotherapy of Cancer

(2020) Shasha He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting apoptosis in cancer therapy

(2020) Benedito A. Carneiro et al.   Nature Reviews Clinical Oncology

Sequential PDT and PTT Using Dual‐Modal Single‐Walled Carbon Nanohorns Synergistically Promote Systemic Immune Responses against Tumor Metastasis and Relapse

(2020) Jingxing Yang et al.   Advanced Science

GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy

(2020) Shuming Dong et al.   ADVANCED MATERIALS

Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers

(2019) Hideaki Ogiwara et al.   CANCER CELL

Targeting Ferroptosis to Iron Out Cancer

(2019) Behrouz Hassannia et al.   CANCER CELL

Nanocatalysts-augmented Fenton chemical reaction for nanocatalytic tumor therapy

(2019) Xiaoqin Qian et al.   BIOMATERIALS

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Combination Immunotherapy: A Dual Immunotherapy Nanoparticle Improves T-Cell Activation and Cancer Immunotherapy (Adv. Mater. 25/2018)

(2018) Yu Mi et al.   ADVANCED MATERIALS

New tools for old drugs: Functional genetic screens to optimize current chemotherapy

(2018) Nora M. Gerhards et al.   DRUG RESISTANCE UPDATES

Expansion, retention and loss in the Acyl-CoA synthetase “ Bubblegum ” ( Acsbg ) gene family in vertebrate history

(2018) Mónica Lopes-Marques et al.   GENE

Glutathione metabolism in cancer progression and treatment resistance

(2018) Ankita Bansal et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanisms driving transcriptional stress responses

(2018) Anniina Vihervaara et al.   NATURE REVIEWS GENETICS

Dual Chemodrug-Loaded Single-Walled Carbon Nanohorns for Multimodal Imaging-Guided Chemo-Photothermal Therapy of Tumors and Lung Metastases

(2018) Jingxing Yang et al.   Theranostics

Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors

(2018) Zheyu Shen et al.   ACS Nano

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

(2018) Shuaifei Wang et al.   ACS Nano

Ferrous-Supply-Regeneration Nanoengineering for Cancer-Cell-Specific Ferroptosis in Combination with Imaging-Guided Photodynamic Therapy

(2018) Tao Liu et al.   ACS Nano

Discovery of 18F-JK-PSMA-7, a novel PET-probe for the detection of small PSMA positive lesions

(2018) Boris D. Zlatopolskiy et al.   JOURNAL OF NUCLEAR MEDICINE

Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy

(2018) Ziliang Dong et al.   NANO LETTERS

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

Tumour heterogeneity and resistance to cancer therapies

(2017) Ibiayi Dagogo-Jack et al.   Nature Reviews Clinical Oncology

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

Synthesis of Iron Nanometallic Glasses and Their Application in Cancer Therapy by a Localized Fenton Reaction

(2016) Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer

(2016) Lingxi Xing et al.   Theranostics

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Preclinical evaluation of a bispecific low-molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer

(2014) Matthias Eder et al.   PROSTATE

Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles

(2013) Maoquan Chu et al.   BIOMATERIALS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases

(2011) Chen Xie et al.   NUCLEIC ACIDS RESEARCH

Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

(2010) Charles E. Hoyle et al.   CHEMICAL SOCIETY REVIEWS

Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart

(2010) Guangwu Wang et al.   CIRCULATION

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Progression-Free Survival as a Predictor of Overall Survival in Men With Castrate-Resistant Prostate Cancer

(2009) Susan Halabi et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Pathophysiological and pharmacological implications of mitochondria-targeted reactive oxygen species generation in astrocytes☆

(2008) Mei-Jie Jou   ADVANCED DRUG DELIVERY REVIEWS

Cellular responses to hyperthermia (40–46°C): Cell killing and molecular events

(2008) Joseph L. Roti Roti   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE