Age‐related differences in the immune response could contribute to determine the spectrum of severity of COVID‐19

Coronavirus infections and immune responses

(2020) Geng Li et al.   JOURNAL OF MEDICAL VIROLOGY

Controlling Cytokine Release Syndrome to Harness the Full Potential of CAR-Based Cellular Therapy

(2020) Monica S. Thakar et al.   Frontiers in Oncology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

(2020) Annsea Park et al.   Cell Host & Microbe

C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

(2020) Bérengère de Laval et al.   Cell Stem Cell

Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients

(2020) Hong-Yi Zheng et al.   Cellular & Molecular Immunology

SARS-COV-2 infection in children and newborns: a systematic review

(2020) Ilaria Liguoro et al.   EUROPEAN JOURNAL OF PEDIATRICS

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

(2020) Janice M. Leung et al.   EUROPEAN RESPIRATORY JOURNAL

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

From SARS to COVID-19: What we have learned about children infected with COVID-19

(2020) Meng-Yao Zhou et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19

(2020) Guoping Li et al.   JOURNAL OF AUTOIMMUNITY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis

(2020) Zhaohai Zheng et al.   JOURNAL OF INFECTION

COVID-19 epidemic: Disease characteristics in children

(2020) Jiatong She et al.   JOURNAL OF MEDICAL VIROLOGY

Hyperinflammatory shock in children during COVID-19 pandemic

(2020) Shelley Riphagen et al.   LANCET

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

(2020) Lucio Verdoni et al.   LANCET

SARS-CoV-2 Infection in Children

(2020) Xiaoxia Lu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Why the immune system fails to mount an adaptive immune response to a COVID‐19 infection

(2020) Pedram Ahmadpoor et al.   TRANSPLANT INTERNATIONAL

Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center’s observational study

(2020) Dan Sun et al.   World Journal of Pediatrics

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

(2020) Alfonso J. Rodriguez-Morales et al.   Travel Medicine and Infectious Disease

Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020

(2020) et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Correction to: SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

(2020) Janko Nikolich-Zugich et al.   GeroScience

Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors

(2020) U. Radzikowska et al.   ALLERGY

The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

(2020) Dennis McGonagle et al.   AUTOIMMUNITY REVIEWS

Two important controversial risk factors in SARS-CoV-2 infection: Obesity and smoking

(2020) Ayse Basak Engin et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research Networks

(2020) Niccolò Parri et al.   EUROPEAN JOURNAL OF PEDIATRICS

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

(2020) Gholam Hossein Meftahi et al.   INFLAMMATION RESEARCH

Obesity and COVID-19: Molecular Mechanisms Linking Both Pandemics

(2020) Andreas Ritter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

(2020) Leora R. Feldstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19 in Children, Pregnancy and Neonates

(2020) Petra Zimmermann et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Clinical manifestations of children with COVID‐19: A systematic review

(2020) Tiago H. Souza et al.   PEDIATRIC PULMONOLOGY

Coronavirus disease 2019 (COVID-19) in children and/or adolescents: a meta-analysis

(2020) Alessandro Mantovani et al.   PEDIATRIC RESEARCH

Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

(2020) Yanwei Li et al.   PHARMACOLOGICAL RESEARCH

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

(2020) Camila Rosat Consiglio et al.   CELL

Trained Innate Immunity, Epigenetics, and Covid-19

(2020) Alberto Mantovani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Obesity aggravates COVID‐19: An updated systematic review and meta‐analysis

(2020) Jun Yang et al.   JOURNAL OF MEDICAL VIROLOGY

Age related human T cell subset evolution and senescence

(2019) Mingde Li et al.   Immunity & Ageing

Mandatory infant & childhood immunization: Rationales, issues and knowledge gaps

(2018) Noni E. MacDonald et al.   VACCINE

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

(2016) Angelo Ravelli et al.   ANNALS OF THE RHEUMATIC DISEASES

Macrophage activation syndrome in the era of biologic therapy

(2016) Alexei A. Grom et al.   Nature Reviews Rheumatology

Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

(2016) Hongjing Gu et al.   Scientific Reports

Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing MiR-4262

(2015) Hong Bao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Critical role of phospholipase A2group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection

(2015) Rahul Vijay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage activation syndrome and cytokine-directed therapies

(2014) Grant S. Schulert et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Enumeration of human peripheral blood dendritic cells throughout the life

(2012) G. Orsini et al.   INTERNATIONAL IMMUNOLOGY

Obesity, inflammation and the immune system

(2012) Fátima Pérez de Heredia et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Amplification of the response to Toll-like receptor ligands by prolonged exposure to interleukin-6 in mice: Implication for the pathogenesis of macrophage activation syndrome

(2011) Raffaele Strippoli et al.   ARTHRITIS AND RHEUMATISM

T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice

(2010) J. Zhao et al.   JOURNAL OF VIROLOGY

SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism

(2010) Xiaolu Lu et al.   VIRUS GENES

B cells and aging: molecules and mechanisms

(2009) Michael P. Cancro et al.   TRENDS IN IMMUNOLOGY

CD28− T cells: their role in the age-associated decline of immune function

(2009) Nan-ping Weng et al.   TRENDS IN IMMUNOLOGY

Mechanisms of immunosenescence

(2009) Calogero Caruso et al.   Immunity & Ageing