Using mitochondrial activity to select for potent human hematopoietic stem cells

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency

(2020) Raymond Liang et al.   Cell Stem Cell

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

(2020) Ashwini Hinge et al.   Cell Stem Cell

Mitochondria in the maintenance of hematopoietic stem cells new perspectives and opportunities

(2019) Marie-Dominique Filippi et al.   BLOOD

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Ca2+–mitochondria axis drives cell division in hematopoietic stem cells

(2018) Terumasa Umemoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regenerating Immunotolerance in Multiple Sclerosis with Autologous Hematopoietic Stem Cell Transplant

(2018) Jennifer C. Massey et al.   Frontiers in Immunology

Improved multilineage human hematopoietic reconstitution and function in NSGS mice

(2018) Mark Wunderlich et al.   PLoS One

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

(2017) Elena Ansó et al.   NATURE CELL BIOLOGY

Mitochondria: back to the future

(2017) Navdeep S. Chandel   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy

(2016) Madhusudhanan Sukumar et al.   Cell Metabolism

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

(2016) Larry L. Luchsinger et al.   NATURE

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing

(2016) Navdeep S. Chandel et al.   NATURE CELL BIOLOGY

Enhancing the efficacy of engraftment of cord blood for hematopoietic cell transplantation

(2016) Hal E. Broxmeyer   TRANSFUSION AND APHERESIS SCIENCE

Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

(2016) José Antonio Bejarano-García et al.   Cell Death & Disease

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

(2016) Nicola Vannini et al.   Nature Communications

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

(2015) Charlie R. Mantel et al.   CELL

CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells

(2015) Elisa Laurenti et al.   Cell Stem Cell

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3

(2015) P. Rimmele et al.   EMBO REPORTS

Stem cells and the impact of ROS signaling

(2014) C. L. Bigarella et al.   DEVELOPMENT

The analysis, roles and regulation of quiescence in hematopoietic stem cells

(2014) A. Nakamura-Ishizu et al.   DEVELOPMENT

Mitochondrial dynamics and inheritance during cell division, development and disease

(2014) Prashant Mishra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009

(2014) Sung-Yun Pai et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry

(2014) Loren Gragert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

(2014) I. Fares et al.   SCIENCE

Divisional History and Hematopoietic Stem Cell Function during Homeostasis

(2014) Jiajing Qiu et al.   Stem Cell Reports

Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress

(2013) I. Tai-Nagara et al.   BLOOD

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Allogeneic hematopoietic cell transplantation for myelofibrosis in the era of JAK inhibitors

(2012) V. Gupta et al.   BLOOD

Umbilical cord blood graft enhancement strategies: has the time come to move these into the clinic?

(2012) M Norkin et al.   BONE MARROW TRANSPLANTATION

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

(2011) Seth W. Perry et al.   BIOTECHNIQUES

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging

(2011) Gudmundur L. Norddahl et al.   Cell Stem Cell

Purified Hematopoietic Stem Cell Transplantation: The Next Generation of Blood and Immune Replacement

(2011) Agnieszka Czechowicz et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Cell cycle regulation in hematopoietic stem cells

(2011) Eric M. Pietras et al.   JOURNAL OF CELL BIOLOGY

Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation

(2011) Hitoshi Takizawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY